Search results for "Reservation"

showing 10 items of 517 documents

The use of normothermic machine perfusion to rescue liver allografts from expanded criteria donors

2021

The use of expanded criteria donors is one of the strategies used to overcome the gap between the demand for organs and the number of donors. Physicians debate the extent to which marginal grafts can be used. In recent years, normothermic machine perfusion (NMP) has been used to test liver viability before transplantation. Grafts underwent NMP whenever histological steatosis was > 40% or there were at least three Eurotransplant criteria for expanded criteria donor (ECD). We used NMP to test 19 grafts, 3 from donation after type 3 controlled cardiac death (DCD), and 16 from donation after brain death (DBD). Only two grafts from DBD were not transplanted, because perfusion proved they were…

medicine.medical_specialtyNormothermic machine perfusionmedicine.medical_treatmentLiver transplantationExpanded Criteria DonormedicineOverall survivalHumansMachine perfusionLiver transplantationbusiness.industryGraft SurvivalOrgan Preservationmedicine.diseaseAllograftsTissue DonorsDonation after brain deathSurgeryTransplantationPerfusionGraft viabilitysurgical procedures operativeLiverExpanded criteria donors Graft viability Hypothermic machine perfusion Liver transplantation Normothermic machine perfusionSurgerySteatosisExpanded criteria donorsbusinessPerfusionHypothermic machine perfusion
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Predictors of live birth in women with a history of biochemical pregnancies after assisted reproduction treatment

2020

Abstract Objectives To ascertain whether women with a history of biochemical pregnancies (BPs) in in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatment cycles have decreased chances of live birth (LB); and (2) to build a predictive model for LB in this particular population of infertile women. Methods In order to achieve the first objective, data from 1536 women that had a LB using autologous fresh or frozen embryos, or dropped out of further IVF/ICSI treatments after completing one to three unsuccessful treatment cycles were retrospectively analyzed. A subpopulation of 90 women that experienced one or more BPs in our assisted reproduction unit were selected to buil…

medicine.medical_specialtyPregnancy Ratemedia_common.quotation_subjectmedicine.medical_treatmentPopulationLogistic regressionIntracytoplasmic sperm injection03 medical and health sciences0302 clinical medicineEmbryo cryopreservationPregnancyHumansMedicine030212 general & internal medicineeducationRetrospective Studiesmedia_commoneducation.field_of_study030219 obstetrics & reproductive medicineIn vitro fertilisationbusiness.industryObstetricsObstetrics and GynecologyEmbryo TransferEmbryo transferLogistic ModelsReproductive MedicineCase-Control StudiesFemaleReproductionLive birthbusinessInfertility FemaleLive BirthEuropean Journal of Obstetrics & Gynecology and Reproductive Biology
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Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and…

2013

Objective To analyze whether assisted conceptions need adjustments in first-trimester Down syndrome screening and why modifications in screening markers occur. Design Eleven-year cohort retrospective analysis. Setting Maternal-fetal medicine unit. Patient(s) Two thousand eleven naturally conceived normal singleton pregnancies and 2,042 normal singleton pregnancies achieved with assisted conception: 350 by IUI and 1,692 with IVF (n = 328) or intracytoplasmic sperm injection (ICSI; n=1,364), using nondonor (n = 1,086) or donated ova (n = 606), with fresh (n = 1,432) or frozen (n = 260) embryos. Intervention(s) Comparison of ultrasound and biochemical markers of first-trimester Down syndrome s…

medicine.medical_specialtyPregnancy-associated plasma protein AReproductive Techniques Assistedmedicine.medical_treatmentDown-RegulationFertilization in VitroIntracytoplasmic sperm injectionEmbryo cryopreservationPredictive Value of TestsPregnancyPrenatal DiagnosismedicineHumansPregnancy-Associated Plasma Protein-AChorionic Gonadotropin beta Subunit HumanFalse Positive Reactionsreproductive and urinary physiologyInsemination ArtificialRetrospective StudiesGynecologyDown syndrome screeningAnalysis of VarianceChi-Square DistributionOocyte Donationbusiness.industrySingletonFree βhcgObstetrics and GynecologyPregnancy Trimester FirstReproductive MedicineCohortFemaleHormone therapyDown SyndromebusinessNuchal Translucency MeasurementBiomarkersFertility and sterility
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Influence of artificial blood contamination of the analysis of cerebrospinal fluid

1981

The influence of artificial blood contamination on the quantitative values obtained in the routine examination of the CSF was investigated. On the basis of dilution series from CSF and blood, the correlation between the number of added erythrocytes and the results of leukocyte counts, protein, glucose and IgG estimation was studied. In addition, the influence of the time between CSF sampling and investigation on erythrocytes and leukocytes, IgG, glucose, pH value and ammonia content in CSF contaminated with blood was investigated. The following data relevant to routine examinations resulted: there are linear correlations between the number of erythrocytes artificially added to the CSF and t…

medicine.medical_specialtyTime FactorsBlood contaminationLeukocyte CountsLeukocyte CountCerebrospinal fluidAmmoniaInternal medicinemedicineHumansCSF albuminCerebrospinal Fluidchemistry.chemical_classificationmedicine.diagnostic_testChemistryLumbar punctureTemperatureCerebrospinal Fluid ProteinsHydrogen-Ion ConcentrationAmino acidDilutionCytolysisBloodGlucoseEndocrinologyNeurologyBlood PreservationImmunoglobulin GImmunologyErythrocyte CountNeurology (clinical)Drug ContaminationJournal of Neurology
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Influence of cold ischemia time on complement activation, neopterin, and cytokine release in liver transplantation.

2004

The aim of this study was to determine whether a cold ischemia time (CIT) of12 hours influences the activation of complement as well as the plasma concentrations of neopterin, interleukin (IL)-6, or IL-8 in orthotopic liver transplantation (OLT).Eighteen consecutive patients undergoing OLT using a veno-venous bypass technique were divided into 2 groups: duration of CIT12 hours (group 1; n = 11), and CIT12 hours (group 2; n = 7). Blood samples were drawn preoperatively, 1 minute before, and 120 minutes after reperfusion.Preoperatively, complement split products, neopterin, IL-6, and IL-8 levels did not differ between the groups. At 120 minutes after reperfusion, the concentrations of C3a, SC…

medicine.medical_specialtyTime Factorsmedicine.medical_treatmentIschemiaLiver transplantationGastroenterologyCold Ischemia TimeNeopterinchemistry.chemical_compoundIschemiaInternal medicinemedicineHumansComplement ActivationTransplantationbusiness.industryInterleukinsNeopterinInterleukinOrgan PreservationHypothermiamedicine.diseaseComplement systemLiver TransplantationTransplantationCold Temperaturesurgical procedures operativechemistryLiverImmunologyCytokinesSurgerymedicine.symptombusinessTransplantation proceedings
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Modified cryopreservation and xenotransplantation of human parathyroid tissue.

1999

Introduction: A modified cryopreservation technique for human parathyroid tissue was compared with the standard method using a programmed freezer. Methods: Total parathyroidectomy was performed in three groups of 6-week-old Rowett nude rats. Group I (control) underwent no transplantation of parathyroid tissue (n=9). After 10 days, the rats of groups II (n=15) and III (n=15) underwent xenotransplantation of 20 mg cryopreserved human parathyroid tissue, which had been stored in liquid nitrogen at –196°C for 1–22 months prior to xenotransplantation. The parathyroid tissue was derived from 15 parathyroidectomized patients with renal hyperparathyroidism. Two tissue samples were obtained from eve…

medicine.medical_specialtyXenotransplantationmedicine.medical_treatmentTotal parathyroidectomyTransplantation Heterologouschemistry.chemical_elementCalciumCryopreservationParathyroid GlandsRats NudeInternal medicinemedicineAnimalsHumansCryopreservationParathyroidectomybusiness.industrySignificant differenceIndividual differenceRatsTransplantationEndocrinologychemistryParathyroid HormoneSurgeryHuman ParathyroidCalciumbusinessLangenbeck's archives of surgery
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Orthotope arterialisierte Lebertransplantation bei Ratten mit Stenttechnik der supra- und infrahepatischen v. cava

2003

The aim of this study was to establish a liver transplant model with a reduced warm ischemic period between cold preservation and completed anastomosis. Male brown Norway rats were used. A cuff was fixed in the portal vein, stents were inserted in the A. hepatica, the suprahepatic and infrahepatic v. cava and in the bile duct. After cross clamping of the recipient liver, another stent, occluded by a small pin, was introduced in the recipient suprahepatic v. cava. After ligation of this recipient suprahepatic caval stent the recipient liver was removed and the cold prepared donor liver was pushed forward along the pin and both suprahepatic stents of recipient and donor were connected. Then c…

medicine.medical_specialtybusiness.industryBile ductmedicine.medical_treatmentPortal veinStentAnastomosisSurgerymedicine.anatomical_structureCuffcardiovascular systemmedicineCold preservationcardiovascular diseasesLiving donor liver transplantationLigationbusiness
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Fertility protection: complications of surgery and results of removal and transplantation of ovarian tissue

2017

Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantati…

medicine.medical_specialtymedia_common.quotation_subjectFertilityOvaryMenstruation03 medical and health sciencesGynecologic Surgical Procedures0302 clinical medicinemedicineHumansFertility preservation610 Medicine & healthLaparoscopyOncofertilitymedia_common030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryOvaryFertility PreservationObstetrics and GynecologyCancermedicine.diseaseSurgeryTransplantationmedicine.anatomical_structureReproductive Medicine030220 oncology & carcinogenesisFemalebusinessDevelopmental BiologyReproductive BioMedicine Online
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Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery.

2004

<i>Objective:</i> To investigate whether intravenous steroid and vasoactive therapy in the acute postoperative period improves hearing outcome in patients who develop acute deafness after attempted hearing preservation surgery for acoustic neuroma (AN) through a retrosigmoid or a middle cranial fossa approach. <i>Study Design and Setting:</i> Retrospective controlled study in a tertiary care center. Thirty-six patients who had developed acute deafness after hearing preservation surgery for treatment of an AN were reviewed. Preoperative AAOHNS hearing class was A in 2, B in 2 and D in 32 patients. Twenty-seven patients were treated with prednisolone, hydroxyethyl star…

medicine.medical_specialtymedicine.drug_classHearing lossmedicine.medical_treatmentPrednisoloneVasodilator AgentsAnti-Inflammatory AgentsAcoustic neuromaDeafnessHydroxyethyl Starch DerivativesPostoperative ComplicationsAcoustic neuroma surgeryVasoactiveotorhinolaryngologic diseasesmedicineEvoked Potentials Auditory Brain StemHumansIn patientPentoxifyllineRetrospective StudiesSalvage TherapyHearing preservationChemotherapybusiness.industryNeuroma Acousticmedicine.diseaseSurgeryOtorhinolaryngologyAnesthesiaAcute DiseaseInjections IntravenousCorticosteroidDrug Therapy Combinationmedicine.symptombusinessORL; journal for oto-rhino-laryngology and its related specialties
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Graft rinse prior to reperfusion in liver transplantation: literature review and online survey within the Eurotransplant community

2015

Graft rinse prior reperfusion in liver transplantation (LT) is believed to reduce the incidence of postreperfusion syndrome and improve clinical outcome. A MEDLINE search was performed to obtain a comprehensive review of the published literature dealing with graft rinse in LT. Moreover, all thirty-four LT centers in the Eurotransplant (ET) region were invited to participate in an online survey to whether or not graft rinse is performed and whether further research in the field is needed. Seventeen reports have been found to investigate graft rinse protocols in 1894 LT recipients. Eighteen of the thirty centers that participated in the online survey performed graft rinse prior reperfusion in…

medicine.medical_specialtymedicine.medical_treatmentMEDLINEHTK solutionLiver transplantationlaw.inventionRandomized controlled triallawSurveys and QuestionnairesmedicineHumansMulticenter Studies as TopicRandomized Controlled Trials as TopicInflammationInternetTransplantationbusiness.industryGeneral surgeryOrgan PreservationLiver TransplantationSurgeryEuropeSolutionsClinical PracticeClinical trialReperfusionbusinessLiver FailureTransplant International
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