Search results for "Reso"

showing 10 items of 13841 documents

Brain abscess formation within an endodermal cyst of the frontal lobe: case report.

2009

A 38-year-old man with a right frontal lobe cyst was treated by endoscopic cystoventriculostomy in 1998. Cyst capsule histology revealed surprisingly an endodermal cyst. The patient was reoperated for cyst expansion by endoscopic re-cystoventriculostomy in 2005. In 2007, the patient suffered from brain abscess formation within the cyst which was punctured. The history was positive for a dental infection. In 2008, a recurrent brain abscess in the cyst occurred. The cyst was completely resected. There was no history of trauma or sinusitis. In all, endodermal cysts may mimic a paraxial arachnoid cyst. It may predispose for recurrent brain abscess formation - especially due to bacteraemia. This…

AdultMalePathologymedicine.medical_specialtyMicrosurgeryEpidermal CystBrain AbscessNeurosurgical ProceduresColloid CystsDiagnosis DifferentialArachnoid cystRecurrenceparasitic diseasesEnterobacter cloacaemedicineHumansCystSinusitisCentral Nervous System CystsBrain abscessbusiness.industryEnterobacteriaceae InfectionsHistologyGeneral MedicineAnatomymedicine.diseaseMagnetic Resonance ImagingFrontal LobeRight frontal lobeArachnoid CystsFrontal lobeEndodermal cystSurgeryNeurology (clinical)businessTomography X-Ray ComputedMinimally invasive neurosurgery : MIN
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MRI pattern recognition in multiple sclerosis normal-appearing brain areas

2011

ObjectiveHere, we use pattern-classification to investigate diagnostic information for multiple sclerosis (MS; relapsing-remitting type) in lesioned areas, areas of normal-appearing grey matter (NAGM), and normal-appearing white matter (NAWM) as measured by standard MR techniques.MethodsA lesion mapping was carried out by an experienced neurologist for Turbo Inversion Recovery Magnitude (TIRM) images of individual subjects. Combining this mapping with templates from a neuroanatomic atlas, the TIRM images were segmented into three areas of homogenous tissue types (Lesions, NAGM, and NAWM) after spatial standardization. For each area, a linear Support Vector Machine algorithm was used in mult…

AdultMalePathologymedicine.medical_specialtyMultiple SclerosisScienceNeuroimagingBiostatisticsGrey matterBiologycomputer.software_genreBrain mappingPattern Recognition Automated030218 nuclear medicine & medical imagingWhite matter03 medical and health sciences0302 clinical medicineText miningNeuroimagingVoxelImage Interpretation Computer-AssistedmedicineHumansMultidisciplinarymedicine.diagnostic_testbusiness.industryMultiple sclerosisStatisticsQRBrainMagnetic resonance imagingmedicine.diseaseDemyelinating DisordersMagnetic Resonance Imagingmedicine.anatomical_structureNeurologyCase-Control StudiesMedicineFemalebusinesscomputerCartographyMathematics030217 neurology & neurosurgeryResearch Article
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Multiple sclerosis: High prevalence of the ‘central vein’ sign in white matter lesions on susceptibility-weighted images

2018

Purpose The aim of this study was to determine the occurrence and distribution of the ‘central vein’ sign in white matter lesions on susceptibility-weighted magnetic resonance images in patients with multiple sclerosis (MS) and cerebral small vessel disease (CSVD). Materials and methods T2-weighted and fluid-attenuated inversion recovery magnetic resonance images of 19 MS patients and 19 patients affected by CSVD were analysed for the presence and localisation of focal hyperintense white matter lesions. Lesions were subdivided into periventricular or non-periventricular (juxtacortical, subcortical, deep white matter and cerebellar) distributed. The number and localisation of lesions present…

AdultMalePathologymedicine.medical_specialtyMultiple SclerosisVeins030218 nuclear medicine & medical imagingWhite matterYoung Adult03 medical and health sciences0302 clinical medicinePrevalencemedicineHumansRadiology Nuclear Medicine and imagingIn patientSWI MR SM Central vein sign susceptibility-weighted imaging multiple sclerosis cerebral small vessel disease magnetic resonance imagingVeinAgedRetrospective StudiesHigh prevalencemedicine.diagnostic_testbusiness.industryMultiple sclerosisBrainMagnetic resonance imagingGeneral MedicineMiddle AgedGeneral Neuroimagingmedicine.diseaseMagnetic Resonance ImagingWhite MatterHyperintensitySWI MR SMmedicine.anatomical_structureCerebral Small Vessel DiseasesSusceptibility weighted imagingFemaleNeurology (clinical)business030217 neurology & neurosurgery
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Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease.

2008

Background: Cognitive impairment is common in multiple sclerosis (MS) and adds significantly to the burden of the disease. The ability to predict future cognitive impairment from imaging obtained at disease onset has not been investigated. Methods: 62 patients imaged within 3 months of a clinically isolated syndrome were assessed neuropsychologically 7 years later. Baseline and periodic MRI measures of lesions, atrophy and normal-appearing white and grey matter were regressed against neuropsychological scores to explore the best predictors of cognitive outcome. Results: 28 patients had developed clinically definite MS at follow-up and a further nine met revised McDonald criteria for MS. Def…

AdultMalePathologymedicine.medical_specialtyPediatricsMagnetic Resonance SpectroscopyAdolescentGrey matterNeuropsychological TestsCerebral VentriclesWhite matterCohort StudiesDisability EvaluationAtrophyMultiple Sclerosis Relapsing-RemittingPredictive Value of TestsmedicineHumansProspective StudiesNeurologic ExaminationAspartic AcidClinically isolated syndromeMultiple sclerosisCognitive disorderNeuropsychologyBrainMcDonald criteriaDipeptidesMiddle Agedmedicine.diseaseCognitive impairment: multiple sclerosisMagnetic Resonance ImagingPsychiatry and Mental healthmedicine.anatomical_structureSurgeryFemaleNeurology (clinical)AtrophyPsychologyCognition DisordersInositolFollow-Up StudiesJournal of neurology, neurosurgery, and psychiatry
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Focal myositis of the temporal muscle

1993

Focal myositis is a rare inflammatory disease of the skeletal muscle that may involve any part of the body. We present a 19-year-old man with a short history of a painful pseudotumor in the right temporal region. MRI pictures showed a swollen right temporal muscle and muscle biopsy revealed the characteristic histological and immunocytochemical findings of polymyositis.

AdultMalePathologymedicine.medical_specialtyPhysiologyBiopsyTemporal musclePolymyositisNecrosisCellular and Molecular NeurosciencePhysiology (medical)BiopsymedicineHumansMyositisMuscle biopsyMyositismedicine.diagnostic_testbusiness.industryMusclesSkeletal muscleHistologyMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureNeurology (clinical)businessMuscle & Nerve
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Transfusional Hemochromatosis: Quantitative Relation of MR Imaging Pituitary Signal Intensity Reduction to Hypogonadotropic Hypogonadism

2000

To assess the relationship between magnetic resonance (MR) imaging pituitary signal intensity reduction in patients with transfusional hemochromatosis and the clinical manifestation of hypogonadotropic hypogonadism.Pituitary MR imaging at 0.5 T was performed in 38 consecutive patients affected by secondary hemochromatosis and in 20 healthy volunteers. Serum ferritin levels were estimated in the affected population. Twenty (53%) of the 38 patients had hypogonadotropic hypogonadism diagnosed. Pituitary-to-fat signal intensity ratios were calculated from coronal gradient-echo (GRE) T2*-weighted MR images. The relationship between the quantitative reduction of the pituitary-to-fat signal intens…

AdultMalePathologymedicine.medical_specialtyPituitary glandAdolescentHemochromatosiPopulationSensitivity and SpecificityPituitary Gland AnteriorHypogonadotropic hypogonadismmedicineHumansBlood TransfusionRadiology Nuclear Medicine and imagingChildeducationHemochromatosisFerritineducation.field_of_studymedicine.diagnostic_testbusiness.industryHypogonadismbeta-ThalassemiaTransfusion ReactionBeta thalassemiaMagnetic resonance imagingmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureROC CurveCoronal planeFerritinsFemaleHemochromatosisbusinessNuclear medicineHumanHormoneRadiology
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Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation

2012

Background The human prion diseases are a group of universally fatal neurodegenerative disorders associated with the auto-catalytic misfolding of the normal cell surface prion protein (PrP). Mutations causative of inherited human prion disease (IPD) include an insertion of six additional octapeptide repeats (6-OPRI) and a missense mutation (P102L) with large families segregating for each mutation residing in southern England. Here we report for the first time the neuropsychological and clinical assessments in these two groups. Method The cognitive profiles addressing all major domains were obtained for 26 patients (18 6-OPRI, 8 P102L) and the cortical thickness determined using 1.5T MRI in …

AdultMalePathologymedicine.medical_specialtyPrionsprion diseaseNeuroimagingDiseaseNeuropsychological Testsmedicine.disease_causePrion DiseasesExecutive FunctionYoung AdultHumansMedicineDementiaMissense mutationStrokeMemory DisordersMutationSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryGenetic heterogeneityNeuropsychologyBrainMiddle Agedmedicine.diseaseMagnetic Resonance ImagingUnited KingdomMutagenesis InsertionalPsychiatry and Mental healthFemaleSurgeryNeurology (clinical)Cognition DisordersbusinessExecutive dysfunctionJournal of Neurology, Neurosurgery and Psychiatry
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The effect of surgical suture material on osteoclast generation and implant-loosening

2020

Background: Implant loosening - either infectious or aseptic- is a still a major complication in the field of orthopaedic surgery. In both cases, a pro-inflammatory peri-prosthetic environment is generated by the immune system - either triggered by bacteria or by implant wear particles - which leads to osteoclast differentiation and osteolysis. Since infectious cases in particular often require multiple revision surgeries, we wondered whether commonly used surgical suture material may also activate the immune system and thus contribute to loss of bone substance by generation of osteoclasts. Methods: Tissue samples from patients suffering from infectious implant loosening were collected intr…

AdultMalePathologymedicine.medical_specialtyProsthesis-Related InfectionsOsteolysisimplant-associated infectionOsteoclasts03 medical and health sciences0302 clinical medicineSuture (anatomy)OsteoclastmedicineCathepsin KHumansOrthopedic ProceduresAgedAged 80 and overSuturesbusiness.industryInterleukin-8Cell DifferentiationProstheses and ImplantsGeneral MedicineMiddle Agedmedicine.diseasesurgical suture materialProsthesis FailureResorptionSurgical suturemedicine.anatomical_structureGiant cellOsteoclastFemale030211 gastroenterology & hepatologyImplantosteolysisbusinessResearch PaperInternational Journal of Medical Sciences
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Basilar Artery Diameter Is a Potential Screening Tool for Fabry Disease in Young Stroke Patients

2010

<i>Background:</i> Fabry disease (FD) is a rare hereditary lysosomal storage disease that has been highlighted as a possible etiology of stroke at a young age. Enlarged basilar artery diameters (BADs) have been demonstrated in FD, and we hypothesize that they might be useful for the screening of FD in young stroke patients. The aim of this study was to compare BADs of young stroke patients without FD to those of FD patients and of healthy age-matched controls. <i>Methods:</i> BADs were measured using MR angiography in 3 age- and gender-matched groups: 25 FD patients (aged 36.5 ± 11.0 years), 26 non-FD stroke patients and 20 healthy controls. <i>Results:</i&g…

AdultMalePathologymedicine.medical_specialtyRisk AssessmentSensitivity and SpecificityPredictive Value of TestsRisk FactorsGermanymedicine.arteryInternal medicineLysosomal storage diseaseBasilar arteryHumansMass ScreeningMedicineStrokeRetrospective StudiesAnalysis of VarianceChi-Square Distributionmedicine.diagnostic_testbusiness.industryAge FactorsMagnetic resonance imagingRetrospective cohort studyMiddle Agedmedicine.diseaseMagnetic Resonance ImagingFabry diseaseCerebral AngiographyStrokeNeurologyBasilar ArteryCase-Control StudiesEtiologyCardiologyFabry DiseaseFemaleNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessDilatation PathologicCerebral angiographyCerebrovascular Diseases
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Unusual MRI findings in an immunocompetent patient with EBV encephalitis: a case report.

2011

Abstract Blackground It is well-known that Epstein-Barr virus (EBV) can affect the central nervous system (CNS). Case presentation Herein the authors report unusual timely Magnetic Resonance Imaging (MRI) brain scan findings in an immunocompetent patient with EBV encephalitis. Diffusion weighted MRI sequence performed during the acute phase of the disease was normal, whereas the Fast Relaxation Fast Spin Echo T2 image showed diffuse signal intensity changes in white matter. The enhancement pattern suggested an inflammatory response restricted to the brain microcirculation. Acyclovir and corticosteroid therapy was administered. After three weeks, all signal intensities returned to normal and…

AdultMalePathologymedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaEpstein-Barr virus encephalitis MRI Diffusion-weighted imaginglcsh:Medical technologyMononucleosisSettore MED/17 - Malattie InfettiveencephalitisCentral nervous systemCase Reportmedicine.disease_causeWhite matterImmunocompromised HostNeuroimagingmedicineHumansEpstein-Barr virusRadiology Nuclear Medicine and imagingInfectious Mononucleosismedicine.diagnostic_testbusiness.industrySettore MED/37 - NeuroradiologiaMagnetic resonance imagingmedicine.diseaseEpstein–Barr virusMagnetic Resonance Imagingmedicine.anatomical_structurelcsh:R855-855.5Radiology Nuclear Medicine and imagingDiffusion-weighted imagingbusinessEncephalitisDiffusion MRIMRIBMC medical imaging
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