Search results for "Respiratory system"

showing 10 items of 1829 documents

Assessment of Pulmonary Mechanics and Gastric Inflation Pressure During Mask Ventilation

1995

AbstractIntroduction:Mask ventilation is a procedure routinely used in emergency medicine. Potential hazards are inadequate alveolar ventilation and inflation of the stomach with air, leading to subsequent regurgitation and aspiration. The aim of this study was to measure lung function and gastric inflation pressures during mask ventilation.Methods:For this purpose, 31 patients scheduled for routine urological procedures were studied during induction of anesthesia. Lung function was assessed by recording respiratory flow and pressure directly at the face mask. Gastric inflation was observed with a microphone taped to the epigastric area.Results:Gastric inflation occurred in 22 of the 31 pat…

AdultMaleInflationManometrymedia_common.quotation_subjectmedicine.medical_treatmentRegurgitation (circulation)Respiratory physiologyEmergency NursingLaryngeal MasksPressuremedicineHumansCardiopulmonary resuscitationRespiratory systemMonitoring Physiologicmedia_commonbusiness.industryStomachStomachInsufflationMiddle AgedRespiration ArtificialCompliance (physiology)medicine.anatomical_structureAnesthesiaRespiratory MechanicsEmergency MedicineFemalebusinessAirwayPrehospital and Disaster Medicine
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Respiratory Mechanics, Gastric Insufflation Pressure, and Air Leakage of the Laryngeal Mask Airway

1997

A potential risk of the laryngeal mask airway (LMA) is incomplete mask seal, which causes air leakage or insufflation of air into the stomach. The objective of the present study was to assess respiratory mechanics, quantify air leakage, and measure gastric air insufflation in patients ventilated via the LMA. Thirty patients were studied after induction of anesthesia but prior to any surgical manipulations. After the insertion of the LMA, patients were ventilated with increasing tidal volumes until one of the three following end points were reached: 1) gastric air insufflation, 2) airway pressure > 40 cm H2O, or 3) limitation of further increase in tidal volume by air leakage. The following …

AdultMaleInsufflationLeakAdolescentRespiratory physiologyLaryngeal MasksLaryngeal mask airwayPressureTidal VolumemedicineHumansRespiratory systemTidal volumebusiness.industryStomachStomachInsufflationMiddle Agedrespiratory systemRespiration Artificialmedicine.anatomical_structureAnesthesiology and Pain MedicineAnesthesiaRespiratory MechanicsFemalebusinessAirwayAnesthesia & Analgesia
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Rupture of supra-aortic neck arteries due to lesions caused by tracheal tubes

1984

Haemorrhages from the common carotid or innominate artery caused by tracheal tubes are rare but dramatic complications of head and neck surgery. Patients with metal tracheostomy cannulas or patients in the phase of wound healing after radical tumour resections of the pharynx and larynx run a greater risk. Following extensive tumour resections and radiation of the upper respiratory and digestive tracts in 680 patients, acute bleeding of the larger neck arteries occurred in 18 patients. In four of these cases, fistulae developed in the innominate or common carotid artery. These ruptures were caused by both plastic and metal tracheal tubes.

AdultMaleLarynxmedicine.medical_specialtyHemorrhagePostoperative Complicationsmedicine.arteryIntubation IntratrachealmedicineHumansCommon carotid arteryRespiratory systemLaryngeal NeoplasmsBrachiocephalic TrunkAgedRupturebusiness.industryPharynxGeneral MedicineMiddle AgedSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and neck surgeryDigestive tractCarotid Artery InjuriesbusinessAortic neckArteryThe Journal of Laryngology & Otology
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Isolated hevein-like domains, but not 31-kd endochitinases, are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit syndrome.

2005

Background Individuals with natural rubber latex allergy often have immediate reactions to plant-derived foods and fresh fruits, such as avocado and banana. IgE of these patients has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD). However, evidence on 31-kd endochitinase-induced reactions in vivo is lacking. Objective We sought to assess the clinical significance of 31-kd endochitinases and isolated HLDs in latex-fruit syndrome. Methods The 31-kd endochitinases and corresponding HLDs were purified or produced from avocado, banana, latex, and wheat germ. Skin prick test reactivities against purified proteins were examined in 15 patients with natural rubbe…

AdultMaleLatexImmunologyMolecular Sequence DataEnzyme-Linked Immunosorbent Assaymedicine.disease_causeImmunoglobulin ECross-reactivityMicrobiology03 medical and health sciences0302 clinical medicineFood allergyChitin bindingLatex HypersensitivitymedicineImmunology and AllergyHumansAmino Acid Sequence030304 developmental biologyDNA PrimersSkin Tests0303 health sciencesbiologySequence Homology Amino AcidChemistryPerseaChitinasesfood and beveragesMusaAllergensImmunoglobulin EMiddle Agedmedicine.diseaseIn vitroWheat germ agglutinin3. Good healthProtein Structure Tertiary030228 respiratory systemSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationImmunologybiology.proteinFemaleAntibodyPlant LectinsAnaphylaxisFood HypersensitivityAntimicrobial Cationic PeptidesThe Journal of allergy and clinical immunology
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Tidal Volume Estimation during Helmet Noninvasive Ventilation: an Experimental Feasibility Study

2019

AbstractWe performed a bench (BS) and human (HS) study to test the hypothesis that estimation of tidal volume (VT) during noninvasive helmet pressure support ventilation (nHPSV) would be possible using a turbine driven ventilator (TDV) coupled with an intentional leak single-limb vented circuit. During the BS a mannequin was connected to a lung simulator (LS) and at different conditions of respiratory mechanics, positive end expiratory pressure (PEEP) levels and leaks (30, 50 and 80 L/min). All differences were within the 95% limits of agreement (LoA) in all conditions in the Bland-Altman plot. The overall bias (difference between VT measured by TDV and LS) was 35 ml (95% LoA 10 to 57 ml), …

AdultMaleLeakmedicine.medical_specialtylcsh:MedicineSettore MED/41 - AnestesiologiaPressure support ventilationTherapeuticsRespiratory physiologyManikinsArticlePositive-Pressure Respiration03 medical and health sciences0302 clinical medicineInternal medicineHealthy volunteersTidal VolumemedicineHumanslcsh:SciencePositive end-expiratory pressureTidal volumeMouthpieceVentilators Mechanicalacute respiratory failureMultidisciplinarybusiness.industrylcsh:RhelmetReproducibility of Resultsnoninvasive ventilation030208 emergency & critical care medicineEquipment DesignHealthy Volunteers030228 respiratory systemPreclinical researchRespiratory MechanicsCardiologyFeasibility Studieslcsh:QFemaleHead Protective DevicesNoninvasive ventilationbusinessScientific Reports
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Inhibition of neuropeptide degradation suppresses sweating but increases the area of the axon reflex flare.

2013

The neuropeptides CGRP (calcitonin gene-elated peptide) and substance P (SP) mediate neurogenic inflammation. Both are degraded by the neutral endopeptidase (NEP) which can be blocked by phosphoramidon. The aim was to evaluate the effect of NEP inhibition on sweating and vasodilatation. Dermal microdialysis was performed on the skin of 39 subjects. Two fibres were perfused with phosphoramidon (0.01%, 0.02% or 0.2%), two with saline. Acetylcholine (ACh) was either added to the microdialysis perfusate (n = 30, 10(-2)  m) or thermoregulatory sweating was induced (n = 9). Co-application of phosphoramidon reduced cholinergic and thermoregulatory sweating. However, the flare size - a localized in…

AdultMaleMicrodialysismedicine.medical_specialtyCalcitonin Gene-Related PeptideNeuropeptideSubstance PSweatingDermatologyCalcitonin gene-related peptideSubstance PBiochemistrychemistry.chemical_compoundInternal medicineReflexmedicineHumansProtease InhibitorsMolecular BiologySkinNeurogenic inflammationintegumentary systemChemistryPhosphoramidonGlycopeptidesrespiratory systemAxonsEndocrinologyCholinergicFemaleNeprilysinAcetylcholinemedicine.drugBody Temperature RegulationExperimental dermatology
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Effects of the Breathe Right Nasal Strips on Nasal Ventilation

1997

The Breathe Right nasal strips are more and more commonly used, mainly by athletes, who hope to enhance their physical performance in competition and training. The effect of the device in such situations is uncertain and perhaps somewhat controversial. To investigate the effects of the nasal strips on nasal ventilation, 20 Caucasian individuals were objectively assessed using anterior rhinomanometry and acoustic rhinometry. The results showed a significant increase in all subjects of transnasal airflow and in the average cross-sectional area of the nasal cavity that quantifies objectively the subjective impression of improved nasal breathing. In such patients where an improvement in nasal …

AdultMaleNasal cavityOtolaryngology03 medical and health sciences0302 clinical medicineAcoustic rhinometryotorhinolaryngologic diseasesHumansMedicineFluorometry030223 otorhinolaryngologySubjective impressionmedicine.diagnostic_testbusiness.industryRespirationEquipment DesignMiddle AgedNaphazolinerespiratory systemDilatationNasal DecongestantsTreatment Outcomemedicine.anatomical_structureOtorhinolaryngologyPhysical performance030220 oncology & carcinogenesisAnesthesiaBreathingFemaleNasal CavityNasal ObstructionRhinomanometrybusinessAmerican Journal of Rhinology
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The latent nature of prolonged grief - A taxometric analysis: Results from a representative population sample

2017

Individuals suffering from prolonged grief disorder (PGD) show severe grief reactions after the death of a significant other, even beyond a period of grieving that is within a person's cultural and religious context. In addition to this core element, PGD can manifest in various ways. Symptoms may include persistent preoccupation, intense emotional pain, or impairment in important life domains. The symptoms, furthermore, have to be of culturally or religiously inappropriate extent or severity, taking into account different norms of grieving. PGD is discussed as a distinct diagnostic category in the revision of the International Classification of Diseases (ICD-11). Nosology of PGD has been hi…

AdultMaleNosology050103 clinical psychologyAdolescentInclusion (disability rights)Population samplemedia_common.quotation_subjectContext (language use)Prolonged grief disorderYoung Adult03 medical and health sciences0302 clinical medicineInternational Classification of DiseasesGermanySurveys and QuestionnairesHumans0501 psychology and cognitive sciencesBiological PsychiatryAgedmedia_commonAged 80 and overConceptualizationMental Disorders05 social sciencesMiddle Agedrespiratory system030227 psychiatryPsychiatry and Mental healthPopulation SurveillanceEtiologyFemalelipids (amino acids peptides and proteins)GriefGriefPsychologyBereavementClinical psychologyPsychiatry Research
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Topical Antibiotic, Antifungal, and Antiseptic Solutions Decrease Ciliary Activity in Nasal Respiratory Cells

2002

This study was designed to investigate whether topical solutions, as they are used in the treatment of selected cases of rhinosinusitis, influence nasal mucociliary clearance. The objective of this study was to evaluate the effects of the following topical solutions on the ciliary beat frequency (CBF) of nasal respiratory cells: ofloxacin as an antibiotic; Betadine and hydrogen peroxide (H2O2) as antiseptic; and amphotericin B, itraconazole, and clotrimazole as antifungal solutions. Differences are described between effects of each of these substances and we clarify whether ciliotoxic effects are dose dependent and if they can be reduced or eliminated by diluting the concentration of the a…

AdultMaleOfloxacinAntifungal AgentsMucociliary clearanceItraconazolemedicine.drug_classAntibioticsPharmacologySensitivity and SpecificityMicrobiology03 medical and health sciences0302 clinical medicineAntisepticReference ValuesAmphotericin BAmphotericin BmedicineHumansClotrimazoleRespiratory system030223 otorhinolaryngologyPovidone-IodineCells CulturedDose-Response Relationship Drugbusiness.industryClotrimazoleNasal MucosaOtorhinolaryngologyMucociliary Clearance030220 oncology & carcinogenesisAnti-Infective Agents LocalFemaleOfloxacinItraconazolebusinessmedicine.drugAmerican Journal of Rhinology
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A comparative study of the pharyngeal airway space, measured with cone beam computed tomography, between patients with different craniofacial morphol…

2014

Abstract Purpose The present study aims to determine any existing association between airway dimensions, measured with cone beam computed tomography (CBCT), and the different patient craniofacial morphologies. Material and methods Sixty CBCT (Dental Picasso Master 3D) images, from patients treated at the Orthodontics Master at Valencia University were selected. The program InVivoDental 5.1 was used to visualize sections, analyze three-dimensional images, and perform airway measurements in the three planes of the space. Intra- and interobserver error methods were recorded. After that, measurements at three different levels of the airway (upper, medium, lower) were taken, in both the anteropo…

AdultMalePalate HardCone beam computed tomographyAdolescentClass iiiMalocclusion Angle Class IMandibleMalocclusion Angle Class IIYoung AdultImaging Three-DimensionalImage Processing Computer-AssistedMedicineHumansCraniofacialChildSkull Basebusiness.industryHyoid BoneReproducibility of ResultsVertical DimensionAnatomyrespiratory systemCone-Beam Computed TomographyCross-Sectional StudiesMalocclusion Angle Class IIIOtorhinolaryngologyPharynxSurgeryFemaleOral SurgeryAnatomic LandmarksPalate SoftbusinessAirwayMalocclusionJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
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