Search results for "Response"
showing 10 items of 4136 documents
Therapeutic Drug Monitoring of Kidney Transplant Recipients Using Profiled Support Vector Machines
2007
This paper proposes a twofold approach for therapeutic drug monitoring (TDM) of kidney recipients using support vector machines (SVMs), for both predicting and detecting Cyclosporine A (CyA) blood concentrations. The final goal is to build useful, robust, and ultimately understandable models for individualizing the dosage of CyA. We compare SVMs with several neural network models, such as the multilayer perceptron (MLP), the Elman recurrent network, finite/infinite impulse response networks, and neural network ARMAX approaches. In addition, we present a profile-dependent SVM (PD-SVM), which incorporates a priori knowledge in both tasks. Models are compared numerically, statistically, and in…
Prediction models to analyse the performance of a commercial-scale membrane distillation unit for desalting brines from RO plants
2018
Abstract Desalting brines from Reverse Osmosis (RO) plants is one of the most promising applications of Membrane Distillation (MD) systems. The development of accurate models to predict MD system performances plays a significant role in the design of this kind of industrial applications. In this paper, a commercial-scale Permeate-Gap Membrane Distillation (PGMD) module was modelled by means of two different approaches: Response Surface Methodology (RSM) and Artificial Neural Networks (ANN). Condenser inlet temperature, evaporator inlet temperature, feed flow rate and feed water salt concentration were selected as inputs of the model, while permeate flux and Specific Thermal Energy Consumpti…
Psychometric Properties of an Emotional Adjustment Measure
2007
Item response theory (IRT) provides valuable methods for the analysis of the psychometric properties of a psychological measure. However, IRT has been mainly used for assessing achievements and ability rather than personality factors. This paper presents an application of the IRT to a personality measure. Thus, the psychometric properties of a new emotional adjustment measure that consists of a 28-six graded response items is shown. Classical test theory (CTT) analyses as well as IRT analyses are carried out. Samejima's (1969) graded-response model has been used for estimating item parameters. Results show that the bank of items fulfills model assumptions and fits the data reasonably well,…
A Short Measure of Acceptability of Intimate Partner Violence Against Women: Development and Validation of the A-IPVAW-8 Scale
2021
Attitudes of acceptability of intimate partner violence against women (IPVAW) are considered one of the main risk factors of this type of violence. The aim of this study is to develop and validate a short version of the acceptability of IPVAW scale, the A-IPVAW-8, for large scale studies where space and time are limited. A panel of experts were asked to assess item content validity. Two samples were recruited to assemble an 8-item short version of the scale using automated test assembly, and to reassess the psychometric properties of the A-IPVAW-8 in an independent sample. Results showed that the A-IPVAW-8 had adequate internal consistency (α = .72-.76, ω = .73-.81), a stable one-factor la…
The role of thermal contribution in the design of AA2024 friction stir welded butt and lap joints: mechanical properties and energy demand
2022
Although in recent times the use of solid-state welding processes as friction stir welding (FSW) has become increasingly widespread, for some joint morphologies, as lap joints, there are still signifcantly less data available on both process parameters optimization and energy consumption. In the present paper, the authors investigated the possibility of enhancing the joint quality in two diferent confgurations, i.e. lap and butt joints, taking into account specifc thermal contribution (STC) conferred to the weld. Strength, micro-hardness and microstructure were evaluated on the produced AA2024 aluminum alloys butt and lap joints. The surface response method (RSM) was used to investigate the…
Path Integral Method for Nonlinear Systems Under Levy White Noise
2017
In this paper, the probabilistic response of nonlinear systems driven by alpha-stable Lévy white noises is considered. The path integral solution is adopted for determining the evolution of the probability density function of nonlinear oscillators. Specifically, based on the properties of alpha-stable random variables and processes, the path integral solution is extended to deal with Lévy white noises input with any value of the stability index alpha. It is shown that at the limit when the time increments tend to zero, the Einstein–Smoluchowsky equation, governing the evolution of the response probability density function, is fully restored. Application to linear and nonlinear systems under…
Stochastic response of a fractional vibroimpact system
2017
Abstract The paper proposes a method to investigate the stochastic dynamics of a vibroimpact single-degree-of-freedom fractional system under a Gaussian white noise input. It is assumed that the system has a hard type impact against a one-sided motionless barrier, which is located at the system’s equilibrium position; furthermore, the system under study is endowed with an element modeled with fractional derivative. The proposed method is based on stochastic averaging technique and overcome the particular difficulty due to the presence of fractional derivative of an absolute value function; particularly an analytical expression for the system’s mean squared response amplitude is presented an…
Heterogeneous structures studied by an interphase elasto-plastic damaging model
2013
Heterogeneous materials present a mechanical response strongly dependent on the static and kinematic phenomena occurring in the constituents and at their joints. At the mesoscopic level the interaction between the units is simulated by mean of apposite mechanical devices such as the zero thickness interface model where contact tractions and displacement discontinuities are the primary static and kinematic variables respectively. In heterogeneous materials the response also depends on joint internal stresses. The introduction of internal stresses brings to the interphase model or an enhancement of the classical zero-thickness interface. With the term 'interphase' we shall mean a layer separa…
Identification of Altered Evoked and Non-Evoked Responses in a Heterologous Mouse Model of Endometriosis-Associated Pain.
2022
The aim of this study was to develop and refine a heterologous mouse model of endometriosis-associated pain in which non-evoked responses, more relevant to the patient experience, were evaluated. Immunodeficient female mice (N = 24) were each implanted with four endometriotic human lesions (N = 12) or control tissue fat (N = 12) on the abdominal wall using tissue glue. Evoked pain responses were measured biweekly using von Frey filaments. Non-evoked responses were recorded weekly for 8 weeks using a home cage analysis (HCA). Endpoints were distance traveled, social proximity, time spent in the center vs. outer areas of the cage, drinking, and climbing. Significant differences between groups…
Hydrological response to an abrupt shift in surface air temperature over France in 1987/88.
2015
10 pages; International audience; During the last few decades, Europe has seen a faster increase of observed temperature than that simulated by models. The air temperature over Western Europe showed an abrupt shift at the end of the 1980s, still insufficiently documented. The aim of this study is to assess the characteristics of this shift and its potential impacts on the hydrological cycle over France. Such an assessment is essential for a better understanding of past and future climatic changes and their impact on water resources.A subset of 119 temperature, 122 rainfall, and 30 hydrometric stations was studied, over the entire French metropolitan territory. Several change-point detection…