Search results for "Response"

showing 10 items of 4136 documents

Three-dimensional point spread function and generalized amplitude transfer function of near-field flat lenses.

2010

We derive a nonsingular, polarization-dependent, 3D impulse response that provides unambiguously the wave field scattered by a negative-refractive-index layered lens and distributed in its image volume. By means of a 3D Fourier transform, we introduce the generalized amplitude transfer function in order to gain a deep insight into the resolution power of the optical element. In the near-field regime, fine details containing some depth information may be transmitted through the lens. We show that metamaterials with moderate absorption are appropriate for subwavelength resolution keeping a limited degree of depth discrimination.

Point spread functionPhysicsbusiness.industryMaterials Science (miscellaneous)Physics::OpticsMetamaterialTransfer functionIndustrial and Manufacturing Engineeringlaw.inventionLens (optics)symbols.namesakeFourier transformOpticsAmplitudelawOptical transfer functionsymbolsBusiness and International ManagementbusinessImpulse responseApplied optics
researchProduct

Ship Roll Motion under Stochastic Agencies Using Path Integral Method

2009

The response of ship roll oscillation under random ice impulsive loads modeled by Poisson arrival process is very important in studying the safety of ships navigation in cold regions. Under both external and parametric random excitations the evolution of the probability density function of roll motion is evaluated using the path integral (PI) approach. The PI method relies on the Chapman-Kolmogorov equation, which governs the response transition probability density functions at two close intervals of time. Once the response probability density function at an early close time is specified, its value at later close time can be evaluated. The PI method is first demonstrated via simple dynamica…

Poisson arrival proceRoll oscillationOscillationDynamics (mechanics)Motion (geometry)Probability density functionPath integral methodWhite noiseWhite noise excitationResponse amplitude operatorRandom excitationControl theoryShip roll motionTransition probabilitiePath integral formulationChapman-Kolmogorov equationMathematicsParametric statistics
researchProduct

Path integral solution for nonlinear systems under parametric Poissonian white noise input

2016

Abstract In this paper the problem of the response evaluation in terms of probability density function of nonlinear systems under parametric Poisson white noise is addressed. Specifically, extension of the Path Integral method to this kind of systems is introduced. Such systems exhibit a jump at each impulse occurrence, whose value is obtained in closed form considering two general classes of nonlinear multiplicative functions. Relying on the obtained closed form relation liking the impulses amplitude distribution and the corresponding jump response of the system, the Path Integral method is extended to deal with systems driven by parametric Poissonian white noise. Several numerical applica…

Poisson white noiseMonte Carlo methodAerospace EngineeringOcean EngineeringProbability density function02 engineering and technologyImpulse (physics)01 natural sciencesPath integral solution0203 mechanical engineering0103 physical sciencesApplied mathematics010301 acousticsCivil and Structural EngineeringMathematicsParametric statisticsMechanical EngineeringMathematical analysisStatistical and Nonlinear PhysicsWhite noiseCondensed Matter PhysicsJump responseNonlinear system020303 mechanical engineering & transportsParametric inputNuclear Energy and EngineeringPath integral formulationNonlinear system
researchProduct

Polarizability and optical rotation calculated from the approximate coupled cluster singles and doubles CC2 linear response theory using cholesky dec…

2004

A new implementation of the approximate coupled cluster singles and doubles CC2 linear response model using Cholesky decomposition of the two-electron integrals is presented. Significantly reducing storage demands and computational effort without sacrificing accuracy compared to the conventional model, the algorithm is well suited for large-scale applications. Extensive basis set convergence studies are presented for the static and frequency-dependent electric dipole polarizability of benzene and C60, and for the optical rotation of CNOFH2 and (−)-trans-cyclooctene (TCO). The origin-dependence of the optical rotation is calculated and shown to persist for CC2 even at basis set convergence. …

PolarisabilityChemistryUNESCO::FÍSICAGeneral Physics and AstronomyComputational physicsDipolePhysics and Astronomy (all)Coupled clusterCoupled cluster calculationsFullerene compoundsOptical rotation ; Coupled cluster calculations ; Organic compounds ; Polarisability ; Fullerene compoundsComputational chemistryPolarizability:FÍSICA [UNESCO]Convergence (routing)Organic compoundsOptical rotationPhysical and Theoretical ChemistryLinear response theoryOptical rotationBasis setCholesky decomposition
researchProduct

Human Drug Pollution in the Aquatic System: The Biochemical Responses of Danio rerio Adults

2021

Simple Summary The release of medicinal products for human use in the aquatic environment is now a serious problem, and can be fatal for the organisms that live there. Danio rerio is a freshwater fish that provides the possibility to study the effects of these pollutants on the health of aquatic organisms. The results of the various existing scientific studies are scarce and conflicting. Here, we review the scientific studies that have analyzed these effects, highlighting that the impacts of drugs are evident in the biochemical responses of these animals. Abstract To date, drug pollution in aquatic systems is an urgent issue, and Danio rerio is a model organism to study the toxicological ef…

PollutantPollutionoxidative streGeneral Immunology and MicrobiologybiologyQH301-705.5media_common.quotation_subjectDanioReviewcortisolbiology.organism_classificationzebrafishGeneral Biochemistry Genetics and Molecular Biologyimmune responseenzymeDrug concentrationpharmaceutically active compounds (PhAC)Environmental healthoxidative stressDrug pollutionBiology (General)General Agricultural and Biological SciencesTotal proteinmedia_commonBiology
researchProduct

Shipping noise affecting immune responses of European spiny lobster (Palinuruselephas)

2015

Marine crustaceans are influenced by numerous environmental factors. Environmental stress from pollutants seems to affect their metabolism, growth, moulting, survival, and immune defence. Recently, it has become clear that there is an impact of the global increase in sea noise levels due to shipping traffic on crustacean welfare. Considering the ecological and commercial importance of the European spiny lobster (Palinurus elephas (Fabricius, 1787)) in most parts of the Mediterranean coastal area, in the present study we investigated whether shipping noise pollution contribute to changing the immune parameters of stress in the European spiny lobster. The animals were exposed to a mix of nois…

Pollutantanimal structuresbiologyEcologyPalinurus elephafungiPalinurus elephasSettore BIO/05 - ZoologiaAquatic animalbiology.organism_classificationCrustaceanEuropean spiny lobsterImmune systemNoise pollutionPO activityAnimal Science and ZoologyHsp27Immune responseSpiny lobsterMoultingEcology Evolution Behavior and SystematicsShellfishCanadian Journal of Zoology
researchProduct

TBBPA causes neurotoxic and the apoptotic responses in cultured mouse hippocampal neurons in vitro

2015

Abstract Background Tetrabromobisphenol A (TBBPA) is a brominated flame retardant widely used in a variety of commercial and household products. TBBPA can become bioaccumulated in human body fluids, and also in different brain regions. The aim of the present study was to determine the viability and apoptosis of cultured mouse hippocampal neurons in vitro after exposure to TBBPA. Additionally, we examined the involvement of ROS generation in the effect of TBBPA. Methods Primary hippocampal neuron cultures were prepared from Swiss mouse embryos on day 17/18 of gestation. The cultures were treated with TBBPA at concentrations ranging from 1 nM to 100 μM for 30 min or 3, 6 or 24 h. To study apo…

Polybrominated BiphenylsApoptosis010501 environmental sciencesHippocampal formationBiology01 natural sciencesHippocampus03 medical and health scienceschemistry.chemical_compoundMice0302 clinical medicineLactate dehydrogenaseAnimalsCells Cultured0105 earth and related environmental sciencesFlame RetardantsPharmacologyNeuronsDose-Response Relationship DrugGeneral MedicineApoptotic bodyMolecular biologyIn vitrochemistryApoptosisEnvironmental chemistryBrominated flame retardantTetrabromobisphenol A030217 neurology & neurosurgeryIntracellularPharmacological Reports
researchProduct

Polypeptoid-block-polypeptide Copolymers: Synthesis, Characterization, and Application of Amphiphilic Block Copolypept(o)ides in Drug Formulations an…

2013

We report the synthesis of polysarcosine-block-polyglutamic acid benzylester (PSar-block-PGlu(OBn)) and polysarcosine-block-polylysine-ε-N-benzyloxycarbonyl (PSar-block-PLys(Z)) copolymers. The novel polypeptoid-block-polypeptide copolymers (Copolypept(o)ides) have been synthesized by ring-opening polymerization (ROP) of N-carboxyanhydrides (NCAs). Polymerization conditions were optimized regarding protecting groups, block sequence and length. While the degree of polymerization of the PSar block length was set to be around 200 or 400, PGlu(OBn) and PLys(Z) block lengths were varied between 20 to 75. The obtained block copolymers had a total degree of polymerization of 220-475 and dispersity…

Polymers and PlasticsCell SurvivalPolymersSurface PropertiesChemistry PharmaceuticalDispersityBioengineeringDegree of polymerizationBiomaterialsPeptoidsStructure-Activity RelationshipSurface-Active AgentsColloidCell Line TumorBlock (telecommunications)AmphiphilePolymer chemistryMaterials ChemistryCopolymerHumansParticle SizeDose-Response Relationship DrugChemistryMiniemulsionHEK293 CellsPolymerizationEmulsionsPeptidesBiomacromolecules
researchProduct

Supramolecular Assemblies Based on Complexes of Nonionic Amphiphilic Cyclodextrins and a meso-Tetra(4- sulfonatophenyl)porphine Tributyltin(IV) Deriv…

2013

Amphiphilic cyclodextrin (ACyD) provides water-soluble and adaptable nanovectors by modulating the balance between the hydrophobic and hydrophilic chains at both CyD sides. This work aimed to design nanoassemblies based on nonionic and hydrophilic ACyD (SC6OH) for the delivery of a poor-water-soluble organotin(IV)-porphyrin derivative [(Bu3Sn)4TPPS] to melanoma cancer cells. To characterize the porphyrin derivatives under simulated physiological conditions, a speciation was performed using complementary techniques. In aqueous solution (≤ 20 μM), (Bu3Sn)4TPPS primarily exists as a monomer (2 in Figure 1), as suggested by the low static anisotropy (ρ ≈ 0.02) with a negligible formation of por…

Polymers and PlasticsCell SurvivalSurface PropertiesPotentiometric titrationSupramolecular chemistryAntineoplastic AgentsBioengineeringBiomaterialsStructure-Activity RelationshipSurface-Active Agentschemistry.chemical_compoundDrug Delivery SystemsAmphiphilePolymer chemistryTumor Cells CulturedMaterials ChemistryHumansOrganic chemistryParticle SizeMelanomaMELANOMA porphyrins organotin(IV)Cell Proliferationchemistry.chemical_classificationCyclodextrinsAqueous solutionCell DeathDose-Response Relationship DrugMolecular StructureCyclodextrinPorphyrinNanomedicineMonomerchemistrySettore CHIM/03 - Chimica Generale E InorganicaDrug Screening Assays AntitumorTrialkyltin CompoundsDrug carrier
researchProduct

Simultaneous determination of main phenolic acids and flavonoids in tomato by micellar electrokinetic capillary electrophoresis

2017

[EN] A methodology for the determination of tomato phenolic acids and flavonoids has been developed combining MEKC and DAD detection. The influence on polyphenol separation of pH and background electrolyte, BGE (borax, acetonitrile, methanol and SDS concentrations), was studied and optimized using response surface methodology and weighted desirability function. Separation of polyphenols was achieved within 20 min at 15 degrees C using 11.3 mM borax and 11.2 mM SDS adjusted to pH 8.5 as BGE. Validation was performed using standards and tomato extracts. Recoveries ranged from 77 to 106%. Acceptable repeatabilities were obtained for peak area (% RSD <3.1% and <3.7%) and migration times (% RSD …

Polyphenol01 natural sciencesPlant breedingAnalytical ChemistryMEKCElectrokinetic phenomena0404 agricultural biotechnologyCapillary electrophoresisSolanum lycopersicumPhenolsResponse surface methodologyHydroxybenzoatesResponse surface methodologyMicellesFlavonoidsChromatographyChemistryPlant Extracts010401 analytical chemistryElectrophoresis Capillary04 agricultural and veterinary sciencesGeneral Medicine040401 food science0104 chemical sciencesGENETICAFunctional qualityPolyphenolFood Science
researchProduct