Search results for "Retina"

The role of glia, mitochondria, and the immune system in glaucoma.

2009

Author(s): Tezel, Gulgun; Fourth ARVO/Pfizer Ophthalmics Research Institute Conference Working Group

Divergent distribution of cytoglobin and neuroglobin in the murine eye

2005

Neuroglobin (Ngb) and cytoglobin (Cygb) are two vertebrate globins with yet poorly defined functions. Previous studies had demonstrated a high expression level of neuroglobin in the mammalian retina, being in line with a respiratory function. Here we show that in the mouse eye, cytoglobin is localised in fibroblasts of the ciliary processes and the choroidea. In the neuronal retina, cytoglobin is expressed in a subset of neurons of the ganglion cell and inner nuclear layers. Cytoglobin is also present in the inner plexiform layer, but absent from the pigment cells. Neuroglobin is localised in photoreceptor inner segments, the plexiform layers and the ganglion cell layer. The divergent distr…

Plasma gangliosides and age-related macular degeneration

2013

Purpose Age-related macular degeneration (AMD) is a multifactorial and polygenic disease and is the main cause of vision loss in developed countries after 50 years old. Indeed, dry AMD leads to progressive retinal atrophy and exsudative AMD induces a rapid alteration of the macula through neovascularisation. Gangliosides (GG) make a wide and heterogeneous family of sialic-acid-containing glycosphingolipids, composed of a sugar chain branched on a ceramide. They are major components of cellular membranes and are particularly abundant in the brain and nervous tissue, including retina. They are also found circulating in the plasma. GG are known for their neuroprotective properties in the nervo…

Visual information flow in Wilson-Cowan networks.

2020

In this paper, we study the communication efficiency of a psychophysically tuned cascade of Wilson-Cowan and divisive normalization layers that simulate the retina-V1 pathway. This is the first analysis of Wilson-Cowan networks in terms of multivariate total correlation. The parameters of the cortical model have been derived through the relation between the steady state of the Wilson-Cowan model and the divisive normalization model. The communication efficiency has been analyzed in two ways: First, we provide an analytical expression for the reduction of the total correlation among the responses of a V1-like population after the application of the Wilson-Cowan interaction. Second, we empiri…

Time response of the vision binocularity by use of dynamic suppression of retinal images

1999

We present a novel technique for determination the stereopsis dynamic response, using as stimulus a random dot stereopair. Stereopsis can be evoked or depressed by continuous or flash illumination of the stimulus with simultaneous control of a special light scattering obstacle build in the visual path of one eye. The obstacle--a thin plate of electrooptical PLZT ceramics-- exposes (by applying of the voltage to semitransparent gold electrodes deposited on both surfaces of the plate) light scattering so blurring the retinal image, similar as for an eye with a cataract, depressing stereopsis. The random dot stereopair contains contours of images with a different stereodisparity. The PLZT plat…

Optical coherence tomography in congenital hypertrophy of the retinal pigment epithelium.

2014

CONVENTIONAL INTERNAL LIMITING MEMBRANE PEELING VERSUS INVERTED FLAP FOR SMALL-TO-MEDIUM IDIOPATHIC MACULAR HOLE

2022

Purpose: To compare conventional internal limiting membrane (ILM) peeling versus inverted flap technique in small-to-medium idiopathic macular hole. Methods: Eyes with ≤400 μ m idiopathic macular holes were randomized into the conventional ILM peeling group (25 eyes) and inverted flap group (25 eyes). A 12-month follow-up was considered. Macular sensitivity (MS) change detected with MP-1 microperimetry was the primary outcome. Secondary outcomes included best-corrected visual acuity change, closure rate, anatomical findings on optical coherence tomography such as U-shape foveal contour, restoration of external limiting membrane, and ellipsoid zone. Results: In both groups, MS improved throu…

Peripapillary Staphyloma and Asymmetric Morning Glory Anomaly

2006

We report a patient with concomitant occurrence of peripapillary staphyloma and morning glory anomaly. The morning glory anomaly presented with an optic nerve head with oblique entrance, located on one side of the peripapillary staphyloma, giving an unusually asymmetric and previously undescribed appearance to the abnormality. The optical coherence tomography provided useful information about the shape and deepness of the peripapillary staphyloma and disclosed a retinal detachment not appreciated ophthalmoscopically.

Incidence of retinal artery occlusion in Germany

2020

Vitrektomie und Membrane Peeling epiretinaler Gliosen nach konservativer Amotiochirurgie

2001

Ziel Die Prufung der Effizienz der Macular—pucker Chirurgie bei sekundaren Gliosen nach Plombenversorgung rhegmatogener Netzhautablosungen.