Search results for "Retina"
showing 10 items of 864 documents
BARDET-BIEDL SYNDROME – CASE PRESENTATION
2015
Bardet-Biedl syndrome (autosomal-recessive inheritance) is characterized by obesity, retinal dystrophy, polydactyly and mental retardation. The authors emphasize the necessary steps in order to establish the diagnosis for an infant with overweight, polydactyly and hypo-genitalism.
Estudio citoarquitectural de la retina del ratón en relación a la disponibilidad del sustrato del receptor de la insulina (IRS2). Nuevas perspectivas…
2014
Título: Estudio citoarquitectural de la retina del ratón en relación a la disponibilidad del sustrato del receptor de la insulina (IRS2). Nuevas perspectivas para las enfermedades retinianas. Propósito: Investigar los cambios retinianos en los ratones adultos homocigotos para la delección de IRS2 (IRS2-/-) en comparación con ratones control. Metodología: Fueron utilizados en este estudio ratones IRS2-/- de 12 semanas de edad y ratones controles C57BL/6J. Las retinas fueron procesadas para técnicas de inmunohistoquímica, y examinadas al microscopio óptico usando anticuerpos específicos para la identificación de filamentos intermedios de las células gliales (proteína ácida fibrilar glial; GFA…
Electroretinography in newborn and young infants without sedation
2009
International audience; Purpose: Electroretinography (ERG) is frequently a relevant diagnostic test in pediatric ophthalmology and neurology. ERG at early age is not easy to perform and requires simplified recording protocols and specific norms. In our laboratory especially devoted to developmental studies, an ERG recording method has been adapted to the very young infant. Methods: Monocular ERG was performed in 60 healthy subjects from birth at term to 3 years of age. ERG was recorded using disposable contact lens electrodes in the conscious child with eyes open, after topical anesthesia but without sedation. Stimulus was a white flash (color temperature 5600°K, energy at source 0.3J) appl…
Inhibitory effect of hydrocortisone administered in ovo on thymidine kinase in chick embryo retina during development
1985
hydrocortisone
Arylalkylamine N-acetyltransferase gene expression in retina and pineal gland of rats under various photoperiods
2004
Abstract The present study examines how the circadian oscillators in the retina and the suprachiasmatic nucleus (SCN) respond to changes in photoperiod. ArylalkylamineN-acetyltransferase (aa-nat) gene expression studied by quantitative RT-PCR revealed that in adult Sprague–Dawley rats kept under different light–dark (LD) cycles for two weeks the temporal pattern of AA-NAT mRNA expression was identical in retina and pineal gland. In both tissues, the time span between the onset of darkness and the nocturnal rise in AA-NAT mRNA expression was 3 h under LD 20:4, 6 h under LD 12:12, and 15 h under LD 4:20. As aa-nat expression in the pineal gland is regulated by the circadian oscillator in SCN,…
Valor del grosor de la capa de fibras nerviosas de la retina medido mediante tomografía de coherencia óptica como marcador de daño neuroaxonal en la …
2012
Estudio del valor del grosor de la Capa de Fibras Nerviosas de la Retina (CFNR) a lo largo de un año como marcador de daño neuroaxonal en pacientes con distintos estadios de Esclerosis Múltiple (EM): pacientes con síndrome clínico aislado (CIS) que es el estadio más inicial de enfermedad desmielinizante, pacientes con esclerosis múltiple remitente-recurrente (EMRR) y pacientes con esclerosis múltiple primaria-progresiva (EMPP) frente a sujetos sanos. Estudio de las posibles correlaciones existentes con otros parámetros como la latencia de la onda P100 de los potenciales evocados visuales (PEV) como marcador de desmielinización, con el volumen cerebral de sustancia gris y de sustancia blanca…
Gap junction intercellular communication (GJIC) is regulated by plasmalogens in retinal macroglial cells
2019
International audience
AUTOMATIC RETINA EXUDATES SEGMENTATION WITHOUT A MANUALLY LABELLED TRAINING SET
2011
International audience; Diabetic macular edema (DME) is a common vision threatening complication of diabetic retinopathy. In a large scale screening environment DME can be assessed by detecting exudates (a type of bright lesions) in fundus images. In this work, two new methods for the detection of exudates are presented. The methods do not require a lesion training set so the need to ground-truth data is avoided with significant time savings and independence from human error. We evaluate our algorithm with a new publicly available dataset from various ethnic groups and levels of DME. Also, we compare our results with two recent exudate segmentation algorithms on the same dataset. In all of …
Visual Health Nanocomposites: Present and Future
2021
Background: In recent years, the therapeutics for eye diseases as retinopathy diabetic, dry eye, glaucoma and contact lenses fabrication are including nanocompounds as ocular drug delivery systems, biomarkers for detection of eye diseases, copper and silver ions that has been incorporated by means of the nanotechnology for the production of less toxic and more effective alternatives. Several compounds such as silver nanoparticles, turmeric-based nanocomposites, neovascularization blockers and nanoparticles extracted from the plant Costus pictus among others have been researched for this purpose. Those compounds are some of the promising research efforts that are studying and will contribute…
Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patt…
2007
To show the existence of IgG antibodies against retinal antigens in aqueous humor of normal tension glaucoma patients.Forty-two patients were included in this study. Aqueous humor was collected from control subjects (CO; n = 21) and patients with normal tension glaucoma (NTG; n = 21). Western blot methods against bovine retinal antigens were used to detect the IgG antibody patterns. The complex antibody repertoires were analyzed by multivariate statistical techniques. Mass spectrometry was used to identify the most important antigens.Very complex IgG antibody patterns against retinal antigens were found in all analyzed aqueous humor samples. Our multivariate approach could quantify differen…