Search results for "Retroperitoneal"

showing 10 items of 43 documents

Annulate Lamellae in a Desmoplastic Small Round Cell Tumor

2016

0301 basic medicineAdultPathologymedicine.medical_specialtyOncogene ProteinsDesmoplastic small-round-cell tumorAnnulate lamellaOncogene Proteins FusionBiologyDesmoplastic Small Round Cell TumorPathology and Forensic Medicine03 medical and health sciences0302 clinical medicineNeoplasm RecurrenceMicroscopy Electron TransmissionmedicineBiomarkers TumorHumansRetroperitoneal NeoplasmsReverse Transcriptase Polymerase Chain Reactionmedicine.diseaseImmunohistochemistryRetroperitoneal Neoplasm030104 developmental biology030220 oncology & carcinogenesisImmunohistochemistrySurgeryFemaleAnatomyNeoplasm Recurrence Local
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Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highli…

2017

Abstract Background Preclinical models that mimic pathological and molecular features of solitary fibrous tumour (SFT) represent an important tool to select effective regimes and novel compounds to be tested in the clinic. This study was aimed at developing two preclinical models of SFT, assessing their predictive value in the clinic and selecting potential novel effective treatments. Material and methods Two dedifferentiated-SFT (D-SFT) models obtained from patients' biopsies were grown in immunodeficient mice. The antitumour activity on these models of doxorubicin, dacarbazine (DTIC), ifosfamide (monotherapy or combination), trabectedin and eribulin was tested. Twelve SFT patients were tr…

0301 basic medicineOncologyMaleCancer Researchmedicine.medical_treatmentSolitary fibrous tumourSoft Tissue NeoplasmsDioxoleMice SCIDPharmacologyAnthracyclineMetastasichemistry.chemical_compound0302 clinical medicineSolitary Fibrous TumorRetrospective StudieTetrahydroisoquinolinesAntineoplastic Combined Chemotherapy ProtocolsTetrahydroisoquinolineMeningeal NeoplasmsMeningeal NeoplasmPleural NeoplasmTrabectedinIfosfamideKidney NeoplasmSarcomaKetonesMiddle AgedMice modelKetoneKidney NeoplasmsDacarbazineSurvival RateOncologyResponse Evaluation Criteria in Solid TumorsSolitary Fibrous Tumors030220 oncology & carcinogenesisFemalemedicine.drugEribulinHumanAdultmedicine.medical_specialtyXenograft Model Antitumor AssayAnthracyclinePleural NeoplasmsDacarbazineBlotting WesternResponse Evaluation Criteria in Solid TumorDioxolesDisease-Free Survival03 medical and health sciencesInternal medicinemedicineAnimalsHumansChemotherapyFuranDoxorubicinRetroperitoneal NeoplasmsEribulinIfosfamideSoft Tissue NeoplasmCerebellar NeoplasmsFuransResponse Evaluation Criteria in Solid TumorsRetrospective StudiesAgedChemotherapyAntineoplastic Combined Chemotherapy ProtocolRetroperitoneal Neoplasmbusiness.industryAnimalXenograftCerebellar NeoplasmXenograft Model Antitumor AssaysTreatment030104 developmental biologychemistryDoxorubicinbusinessTrabectedin
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A very rare cause of retroperitoneal bleeding in young patients: do not forget the occurrence of a ruptured left gastroepiploic artery aneurysm!

2019

Visceral artery aneurysms represent a very rare condition. The affected patients usually present as emergency secondary to the sudden rupture of the aneurysm or as an incidental finding on imaging. In this setting, gastric and gastroepiploic aneurysms account for only about 4% of all the splancnic aneurysms. Since ruptured visceral aneurysms present a high mortality, a prompt and adequate (surgical or radiological interventional) treatment is mandatory. Due to the difficulty in achieving an adequate transcatheter access in some cases the emergency laparotomy may represent the only chance for the recover of the affected patients. We report two cases of ruptured left gastroepiploic aneurysms …

AdultEmergencieMaleLaparotomyRupture SpontaneousRupture SpontaneouHemorrhageAneurysm RupturedYoung AdultSettore MED/18 - Chirurgia GeneraleRare DiseasesRare DiseaseHumansLaparoscopyRetroperitoneal SpaceEmergenciesGastroepiploic ArteryHuman
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Atypical Pleomorphic Extraosseous Ewing Tumor/Peripheral Primitive Neuroectodermal Tumor with Unusual Phenotypic/Genotypic Profile

2002

A pleomorphic undifferentiated tumor primarily located in the retroperitoneum with a phenotype compatible with an extraosseous Ewing tumor/peripheral primitive neuroectodermal tumor (ET/pPNET) pattern and unusual molecular features is described. Immunohistochemically, HBA-71 (CD99/mic2) and several neural markers were intensively expressed together with scattered cells expressing carcinoembryonic antigen (CEA). Short-term culture showed biphasic neuroblastic and epithelioid cell populations, with the latter expressing germ cell markers (CEA, alpha-fetoprotein, and the beta-subunit of chorionic gonadotrophin). Conventional cytogenetics displayed several chromosomic rearrangements, especially…

AdultMalePathologymedicine.medical_specialtyOncogene Proteins FusionChromosomes Human Pair 22CD99Soft Tissue NeoplasmsChromosomal translocationSarcoma EwingBiologyTranslocation GeneticPathology and Forensic MedicineExonFatal OutcomeCarcinoembryonic antigenBiomarkers TumorTumor Cells CulturedmedicineHumansNeuroectodermal Tumors PrimitiveRetroperitoneal NeoplasmsMolecular BiologyGene Rearrangementmedicine.diagnostic_testReverse Transcriptase Polymerase Chain ReactionPeripheral Primitive Neuroectodermal TumorChromosomes Human Pair 11Neoplasms Second PrimaryDNA NeoplasmCell BiologyGenes p53Chromosome Bandingmedicine.anatomical_structureKaryotypingMutationbiology.proteinEpithelioid cellGerm cellFluorescence in situ hybridizationDiagnostic Molecular Pathology
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Bilateral ureteral obstruction and renal failure caused by massive retroperitoneal hematoma: is there a pelvic compartment syndrome analogous to abdo…

1998

Objectives: To describe an intrapelvic compartment syndrome analogous to abdominal compartment syndrome and to characterize its diagnosis and treatment. Design: Retrospective analysis. Setting: Level I trauma center. Patients: Three patients with pelvic ring or acetabular fractures presented with bilateral ureteral obstruction, renal organ failure. and anuria due to direct compression of both ureters in the true pelvis by a massive retroperitoneal hematoma, Intervention: Surgical therapy consisted of fracture stabilization, decompression of the retroperitoneal space, and evacuation of the hematoma. Persistent isolated bleeding points were either embolized preoperatively or ligated. Results:…

AdultMalemedicine.medical_specialtyAbdominal compartment syndromeDecompressionUrologyurologic and male genital diseasesCompartment SyndromesRetroperitoneal hematomaFractures BoneUreterHematomaMedicineRetroperitoneal spaceHumansOrthopedics and Sports MedicinePelvic compartmentRetroperitoneal SpaceCompartment (pharmacokinetics)Pelvic BonesHematomabusiness.industryAcetabulumGeneral MedicineAcute Kidney InjuryMiddle Agedmedicine.diseaseSurgeryRadiographysurgical procedures operativemedicine.anatomical_structureSurgeryAnuriaFemaleRadiologymedicine.symptombusinessKidney diseaseUreteral ObstructionJournal of orthopaedic trauma
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PTFE mesh in renal allograft compartment syndrome.

2006

We report a case of anuria in a 42-year-old female kidney transplant patient that occurred secondary to extrinsic compression from a large kidney being placed extraperitoneally in a small iliac fossa. Prompt reexploration in the immediate postoperative period resulted in salvage of the graft with restoration of kidney function. The abdominal wall was reconstructed using prosthetic mesh, which decreased the compartment pressure within the iliac fossa sufficiently to allow the renal vein patency and the kidney perfusion. We think that this tension-free surgical technique should be applied in those cases in which the retroperitoneal space is less than the size of the kidney to avoid renal allo…

AdultMalemedicine.medical_specialtyIncisional herniaIliac fossaAnuriaCompartment SyndromesRenal DialysismedicineRetroperitoneal spaceHumansTransplantation HomologousPolytetrafluoroethyleneKidney transplantationTransplantationKidneybusiness.industrySurgical Meshmedicine.diseaseKidney TransplantationSurgerymedicine.anatomical_structureSurgical meshSurgeryAnuriaRenal veinmedicine.symptombusinessTransplantation proceedings
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The Value of Sonography and Lymphography in the Detection of Retroperitoneal Metastases in Testicular Tumors

1979

Lymphography has led to falsely negative or falsely positive diagnoses in 10 to 45 per cent of the cases of testicular tumor metastases reported in the literature. In our comparative study of lymphography and sonography in the preoperative staging of 29 malignant testicular tumors lymphography was accurate in 58.5 per cent of the cases, while sonography had an accuracy rate of 82.5 per cent. Sonography was superior to lymphography in the evaluation of hilar lymph node metastases and their extent, as well as for routine checkups after lymphadenectomy or irradiation.

AdultMalemedicine.medical_specialtybusiness.industryUrologymedicine.medical_treatmentLymphographyTesticular tumorDysgerminomaSurgerymedicine.anatomical_structurePreoperative stagingTesticular NeoplasmsLymphatic MetastasismedicineHumansLymph Node ExcisionLymphadenectomyRetroperitoneal NeoplasmsRadiologybusinessLymph nodeUltrasonographyJournal of Urology
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Vena cava resection and bypass for recurrent cervical cancer

2021

A 42-year-old woman was diagnosed with a second para-aortic cervical cancer. The patient had undergone a radical hysterectomy with pelvic lymphadenectomy for FIGO stage IB1 squamous cervical cancer 3 years prior to current presentation. No adjuvant treatment was performed after the primary surgery

Adultmedicine.medical_specialtyVena cavacervical cancerretroperitoneal neoplasms Uterine Cervical NeoplasmUterine Cervical NeoplasmsRecurrent cervical cancerVena Cava InferiorResectionblood vesselgynecologic surgical proceduremedicineHumansStage (cooking)Radical HysterectomyCervical cancerbusiness.industryObstetrics and Gynecologyneoplasm recurrencemedicine.diseaseRetroperitoneal NeoplasmSurgeryOncologyFemaleNeoplasm Recurrence LocalPresentation (obstetrics)businessInternational Journal of Gynecologic Cancer
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Postrenal anuria in pelvic or acetabular injury: a report of three cases.

1996

Renal failure due to obstruction by a retroperitoneal hematoma is a rarely discussed complication in pelvic or acetabular fractures. Three cases of this obstructive uropathy are presented. They were successfully treated with removal of the hematoma and draining of the retroperitoneal space.

Adultmedicine.medical_specialtyurologic and male genital diseasesAnuriaRetroperitoneal hematomaFractures BoneHematomamedicineRetroperitoneal spaceHumanscardiovascular diseasesRetroperitoneal SpacePelvic BonesObstructive uropathyAgedHematomabusiness.industryAccidents TrafficAcetabulumMiddle Agedmedicine.diseaseAcetabulumSurgerybody regionssurgical procedures operativemedicine.anatomical_structurecardiovascular systemAnuriamedicine.symptomComplicationbusinessKidney diseaseThe Journal of trauma
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CT and MR Imaging of Retroperitoneal Sarcomas: A Practical Guide for the Radiologist

2023

Primary retroperitoneal sarcomas (RPS) represent around 10–16% of all sarcomas, with liposarcomas and leiomyosarcomas being the most common subtypes. RPS have some peculiar characteristics, imaging appearances, worse prognosis, and complications compared to other locations of sarcoma. Commonly, RPS primarily present as large masses, progressively encasing adjacent structures, causing mass effect, and complications. RPS diagnosis is often challenging, and these tumors may be overlooked; however, failure to recognize RPS characteristics leads to a worse prognosis for the patients. Surgery is the only recognized curative treatment, but the anatomical constraints of the retroperitoneum limit th…

Cancer ResearchsarcomaOncologycomplicationsliposarcomaleiomyomamagnetic resonance imagingsolitary fibrous tumordifferential diagnosicomputed tomographynerve sheath tumorretroperitoneal neoplasmSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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