Search results for "Retrospective"

showing 10 items of 3553 documents

Questionable Value of Adjuvant Arteriovenous Fistula in Pedal Bypass at High Risk for Early Failure

2007

Results of an adjuvant arteriovenous fistula (AVF) in pedal bypass surgery in the presence of poor status of the recipient artery, severely impaired intraoperative runoff, or revision for early failure and flow restitution were analyzed in a retrospective study. From January 1998 to December 2006, 24 adjuvant AVFs were constructed in autologous vein or composite pedal bypasses with low intraoperative bypass flow, poor status of the pedal artery, or during successful early bypass revision to prevent graft failure. All infrainguinal bypass operations were registered in a computerized database and prospectively followed. Pedal bypasses with adjunctive AVF were reviewed for fistula function, gr…

AdultMaleReoperationmedicine.medical_specialtyTime FactorsFistulamedicine.medical_treatmentArteriovenous fistulaRisk AssessmentAmputation SurgicalVeinsBlood Vessel Prosthesis ImplantationArteriovenous Shunt SurgicalIschemiaOcclusionmedicineHumansVascular PatencyTreatment Failurecardiovascular diseasesVascular PatencyAgedRetrospective StudiesAged 80 and overPeripheral Vascular DiseasesLegbusiness.industryPatient SelectionGraft Occlusion VascularRetrospective cohort studyGeneral MedicineMiddle AgedLimb Salvagemedicine.diseaseSurgerybody regionsmedicine.anatomical_structureAmputationBypass surgeryFemaleSurgeryRadiologyCardiology and Cardiovascular MedicinebusinessArteryAnnals of Vascular Surgery
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Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success.

2015

Background— In the meantime, catheter ablation is widely used for the treatment of persistent atrial fibrillation (AF). There is a paucity of data about long-term outcomes. This study evaluates (1) 5-year single and multiple procedure success and (2) prognostic factors for arrhythmia recurrences after catheter ablation of persistent AF using the stepwise approach aiming at AF termination. Methods and Results— A total of 549 patients with persistent AF underwent de novo catheter ablation using the stepwise approach (2007–2009). A total of 493 patients were included (Holter ECGs ≥every 6 months). Mean follow-up was 59±16 months with 2.1±1.1 procedures per patient. Single and multiple procedu…

AdultMaleReoperationmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentCatheter ablationKaplan-Meier EstimateDisease-Free SurvivalYoung AdultSex FactorsHeart RatePredictive Value of TestsRecurrenceRisk FactorsPhysiology (medical)Internal medicineHeart rateAtrial FibrillationmedicineTachycardia SupraventricularHumans610 Medicine & healthAgedRetrospective StudiesAged 80 and overbusiness.industryAtrial fibrillationRetrospective cohort studyMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeAtrial FlutterPredictive value of testsPersistent atrial fibrillationMultivariate AnalysisCardiologyCatheter AblationElectrocardiography AmbulatoryFemaleCardiology and Cardiovascular MedicinebusinessStepwise approachAnti-Arrhythmia AgentsAtrial flutterFollow-Up StudiesCirculation. Arrhythmia and electrophysiology
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Chronic subdural hematoma--craniotomy versus burr hole trepanation.

2009

The authors present a series of more than 200 surgical procedures for chronic subdural hematoma in a 5-year-period. Clinical presentation and neurosurgical treatment were regarded with a special focus on the surgical technique. Between March 2003 and July 2008, 193 patients (113 male and 80 female, mean age 72.5 yrs [range 26–97 yrs]) suffering from chronic subdural hematoma were retrospectively analyzed. One-hundred-fifty-one craniotomies and 42 burr holes were performed. Forty-two craniotomy patients (27.8%) in contrast to 6 burr hole patients (14.3%) required surgical revision. A craniectomy was performed as an ultima ratio after at least 2 prior evacuations in 3 cases. Chronic subdural …

AdultMaleReoperationmedicine.medical_specialtymedicine.medical_treatmentBurr holesHematomaChronic subdural hematomaRecurrenceTrephiningmedicineHumansCraniotomyAgedRetrospective StudiesAged 80 and overbusiness.industryAge FactorsRetrospective cohort studyMean ageGeneral MedicineSurgical proceduresMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeSubdural hygromaHematoma Subdural ChronicSurgeryFemaleNeurology (clinical)businessTomography X-Ray ComputedCraniotomyBritish journal of neurosurgery
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Predicting the failure in distal femur fractures.

2018

Abstract Introduction The incidence of nonunion after fractures of the distal femur is up to 6%. The distal femoral nonunion is a disabling disease that needs complex steps in his treatment. Aim of our study is to find predicting factors of non-unions. Materials and methods We retrospectively analyzed 116 cases of distal femoral fractures and 20 cases of non-unions. In both surgeries we analyzed: accuracy of reduction, stability of fixation, hardware used, residual medial or lateral bone defect, use of autologous or heterologous bone grafts. Results Malreduction, particularly axial defect, associated with unbalanced fixation, and a medial cortical bone defect of greater or lesser extent wer…

AdultMaleReoperationmedicine.medical_specialtymedicine.medical_treatmentNonunionBone graftingNon union03 medical and health sciencesDistal femurFracture Fixation InternalYoung Adult0302 clinical medicinePostoperative ComplicationsmedicineHumans030212 general & internal medicineTreatment FailureRange of Motion ArticularReduction (orthopedic surgery)General Environmental ScienceFixation (histology)AgedRetrospective StudiesFracture Healing030222 orthopedicsBone Transplantationbusiness.industryMiddle AgedBone defectmedicine.diseaseSurgeryBiomechanical Phenomenasurgical procedures operativemedicine.anatomical_structureFractures UnunitedGeneral Earth and Planetary SciencesCortical boneFemalebusinessBone PlatesFemoral FracturesInjury
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Structure-function relationship between FDF, FDT, SAP, and scanning laser ophthalmoscopy in glaucoma patients.

2012

Purpose Flicker defined form perimetry (FDF) and frequency doubling technology perimetry (FDT) are alleged to detect glaucoma at an earlier stage than standard automated perimetry (SAP). It is the purpose of this study to investigate the structure-function relationship between FDF, FDT, SAP, and confocal scanning laser ophthalmoscopy (cSLO) in patients with glaucoma. Methods Seventy-six patients with glaucoma were included in the study. Patients were tested with SAP, Matrix-FDT, FDF perimetry, and cSLO. Structure-function relationships between global and sectoral cSLO parameters and global and sectoral mean sensitivity (MS) of SAP, Matrix-FDT, and FDF were calculated using Spearman's rank c…

AdultMaleRetinal Ganglion CellsIntraocular pressuremedicine.medical_specialtygenetic structuresGlaucomaOphthalmologyLinear regressionmedicineHumansIn patientTomographyIntraocular PressureMathematicsRank correlationRetrospective StudiesAutomated perimetryStructure functionReproducibility of ResultsGlaucomaMiddle Agedmedicine.diseaseeye diseasesScanning laser ophthalmoscopyOphthalmoscopyVisual Field TestsFemaleVisual FieldsInvestigative ophthalmologyvisual science
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Olfactory Dysfunction After Head Injury

2008

Objective: To determine the incidence of olfactory dysfunction after head trauma using clinical and radiologic findings, quantitative assessment, and electro-physiologic methods. Participants: A total of 190 patients with head trauma of different severity (n = 32 with mild traumatic brain injury (TBI), n = 94 with signs of moderate TBI, and n = 64 with severe TBI) 6 to 32 months prior to the study. Design: Patients were selected retrospectively, surveyed by telephone (n = 190), and screened for olfactory function with Brief Smell Identification Test (n = 82). Those with olfactory dysfunction were assessed as outpatients using the Sniffin' Sticks (n = 19) and olfactory-evoked potential recor…

AdultMaleRiskOlfactory systemmedicine.medical_specialtyTraumatic brain injuryAnosmiaPhysical Therapy Sports Therapy and RehabilitationOlfactionHead traumaCohort StudiesOlfaction DisordersYoung AdultHematomamedicineHumansEvoked PotentialsAgedRetrospective Studiesbusiness.industryIncidence (epidemiology)RehabilitationHead injuryMiddle AgedOlfactory Perceptionmedicine.diseaseIntracranial Hemorrhage TraumaticSurgeryBrain InjuriesSensory ThresholdsAnesthesiaFemaleNeurology (clinical)medicine.symptombusinessJournal of Head Trauma Rehabilitation
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Association between multiple sclerosis, cancer risk, and immunosuppressant treatment: a cohort study

2017

Abstract Background The association between multiple sclerosis (MS) and cancer has long been investigated with conflicting results. Several reports suggest an increased cancer risk among MS patients treated with immunosuppressant (IS) drugs. Methods We performed a cohort study including MS patients recruited at the Neurological Department of the University of Palermo. Mean follow-up period was ten years for the whole cohort. We calculated cancer incidence among patients treated with IS. Incidence rates were compared in the cohort by calculating the relative risk according to length and dose of exposure to IS. Cancer incidence among MS patients was compared to cancer incidence in the general…

AdultMaleRiskmedicine.medical_specialtyMultiple SclerosisPopulationlcsh:RC346-429Cohort StudiesYoung Adult03 medical and health sciences0302 clinical medicineNeoplasmsInternal medicinemedicineHumansMultiple sclerosiCancer; Cohort study; Immunosuppressant; Multiple sclerosis; Treatment; Neurology (clinical)Prospective cohort studyeducationlcsh:Neurology. Diseases of the nervous systemCancerImmunosuppressanteducation.field_of_studybusiness.industryIncidenceMultiple sclerosisCancerRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseSurgeryTreatment030220 oncology & carcinogenesisRelative riskCohortFemaleNeurology (clinical)Cohort studybusinessImmunosuppressive Agents030217 neurology & neurosurgeryResearch ArticleCohort studyBMC Neurology
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Natural history of mesenteric venous thrombosis in patients treated with vitamin K antagonists: a multi-centre, retrospective cohort study.

2009

summaryKnowledge on the natural history of mesenteric vein thrombosis (MVT) and of the efficacy and safety of long-term oral anticoagulant therapy (OAT) in this setting is based on small uncontrolled series of patients with a limited follow-up. It was the aim of the study to assess the natural history of MVT in a cohort of patients treated with OAT. The charts of all MVT patients currently attending or who have attended four anticoagulation clinics were reviewed. Information on risk factors, treatment, recurrence, major bleeding and mortality was collected. Seventyseven patients (mean age 49.2 years; 45 males) were included with a median follow-up of 36 months (range 2–204 months). Forty-si…

AdultMaleRiskmedicine.medical_specialtyVitamin Kmedicine.drug_classmedicine.medical_treatmentSettore MED/15 - Malattie Del SangueCohort StudiesRisk FactorsmedicineHumansVeinAgedRetrospective StudiesAged 80 and overVenous ThrombosisChemotherapybusiness.industryAnticoagulantAnticoagulantsRetrospective cohort studyHematologyMiddle Agedmedicine.diseaseSurgeryMesenteric ArteriesNatural historyVenous thrombosismedicine.anatomical_structuremesenteric vein thrombosisCohortFemalebusinessCohort study
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Sarcopenia as prognostic factor for survival after orthotopic liver transplantation

2020

Background and aim Body composition has emerged as a prognostic factor for end-stage liver disease. We therefore investigated muscle mass, body fat and other clinical-pathological variables as predictors of posttransplant survival. Methods A total of 368 patients, who underwent orthotopic liver transplantation (OLT) at our institution, were assessed prior to OLT and followed for a median of 9.0 years (range 2.0-10.0 years) after OLT. Psoas, erector spinae and the combined paraspinal muscle area, as well as the corresponding indices normalized by body-height squared, were quantified by a lumbar (L3) cross-sectional computed tomography. In addition, absolute body fat and bone density were est…

AdultMaleSarcopeniamedicine.medical_specialtyBone densityUrologyEnd Stage Liver Disease03 medical and health sciencesLiver disease0302 clinical medicineLumbarErector spinae musclesHumansMedicineRetrospective StudiesAnatomy Cross-SectionalHepatologybusiness.industryHazard ratioGastroenterologyHepatitis CMiddle AgedPrognosismedicine.diseaseConfidence intervalLiver Transplantation030220 oncology & carcinogenesisSarcopeniaBody CompositionFemale030211 gastroenterology & hepatologyTomography X-Ray ComputedbusinessEuropean Journal of Gastroenterology & Hepatology
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Smoking habits of parents and male: female ratio in spermatozoa and preimplantation embryos

2005

BACKGROUND Previous observations have addressed a decreased male:female ratio associated with smoking. Our aim was to assess whether this effect is observed at the spermatozoa or at the early embryo development. METHODS We retrospectively assessed smoking intake habits of 56 couples included in our preimplantation genetic diagnosis (PGD) program. Three groups were established according to male or female cigarette consumption per day: non-smokers, smokers (1-19 cigarettes per day) and heavy smokers (> or =20 cigarettes per day). Fluorescence in-situ hybridization (FISH) was performed on ejaculated sperm samples to analyse chromosomes X and Y. On day 3, embryos were also analysed. Additionall…

AdultMaleSemenBiologyPreimplantation genetic diagnosisAndrologyPregnancyCapacitationmedicineHumansSex RatioIn Situ Hybridization FluorescenceRetrospective StudiesChromosomes Human XChromosomes Human Ymedicine.diagnostic_testIncidenceIncidence (epidemiology)SmokingRehabilitationObstetrics and GynecologyEmbryoSpermatozoaSpermBlastocystReproductive MedicineFemaleSex ratioFluorescence in situ hybridizationHuman Reproduction
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