Search results for "Rho"

showing 10 items of 2586 documents

Real-world experience with obeticholic acid in patients with primary biliary cholangitis

2021

Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…

upper limit of normalCirrhosisALTAMAAutoimmunityantinuclear antibodiesULNPBCGastroenterologyUDCASettore MED/12ULN upper limit of normalobeticholic acidaRR adjusted risk ratio.CRFs case record formAST aspartate transferaseClinical endpointGGT gamma-glutamyl transferaseQCprimary biliary cholangitisGastroenterologyUrsodeoxycholic acidANATCCCirrhosisCholestasiTIPSTreatment Completer CohortANA antinuclear antibodiemedicine.medical_specialtyRRUDCA ursodeoxycholic acidTIPS transjugular intrahepatic portosystemic shuntOCACirrhosiALP alkaline phosphataseautoimmune hepatitismedicine.diseasedigestive system diseasesDiscontinuationKeywords: AIH autoimmune hepatitiQC quality controlchemistrygamma-glutamyl transferaserandomised controlled trialelectronic data captureantimitochondrial antibodiesaspartate transferaseAutoimmune hepatitischemistry.chemical_compoundAIHCRFsImmunology and Allergyadjusted risk ratioANA antinuclear antibodiesRR risk ratioOverall cohortALT alanine transferaseAMA antimitochondrial antibodieCholestasisCRFs case record formsObeticholic acidOverlap PBC-AIHursodeoxycholic acidOCA obeticholic acidTolerabilityalkaline phosphataseRCTResearch Articlemedicine.drugcase record formsContext (language use)AMA antimitochondrial antibodiesInternal medicineEDC electronic data capturetransjugular intrahepatic portosystemic shuntInternal MedicinemedicineRCT randomised controlled trialaRR adjusted risk ratioOClcsh:RC799-869quality controlalanine transferaseASTaRRHepatologybusiness.industryAutoimmunity; Cholestasis; Cirrhosis; Overlap PBC-AIHAIH autoimmune hepatitisTCC Treatment Completer CohortPBC primary biliary cholangitiGGTrisk ratioOC Overall cohortALPlcsh:Diseases of the digestive system. GastroenterologyPBC primary biliary cholangitisbusinessEDC
researchProduct

Quartiere in transizione. Il caso di Danisinni (Palermo) tra marginalità socio-spaziale e rigenerazione di comunità

2019

Nelle città contemporanee sempre più complesse e i cui confini diventano sempre più labili, il rafforzamento degli aspetti spazio-relazionali esistenti può divenire il fulcro su cui innestare nuove pratiche e politiche urbane con ricadute multiscalari. A partire dal riconoscimento del quartiere come dimensione di prossimità il presente contributo è una occasione per riflettere sui processi di gestione comunitaria per la riqualificazione urbana che provano a rispondere alle sempre più precarie condizioni di vita delle grandi città. Il caso analizzato, all’interno della neoistituita città metropolitana di Palermo, riguarda il quartiere di Danisinni, in cui depressione spaziale e depressione s…

urban regenerationurban regeneration community neighborhood.communitySettore M-GGR/01 - GeografiaSettore ICAR/21 - UrbanisticaM-GGR/01 - GEOGRAFIAneighborhood
researchProduct

How neighbourhood interactions influence urban sprawl

2011

International audience

urban sprawlneighbourhood interactions[SHS.GEO] Humanities and Social Sciences/Geography[SHS.GEO]Humanities and Social Sciences/GeographyComputingMilieux_MISCELLANEOUS[ SHS.GEO ] Humanities and Social Sciences/Geography
researchProduct

Koulun kerhotoiminta edistämässä valmistavan luokan oppilaiden integroitumista

2017

TIIVISTELMÄ Hukkanen, Sara. 2017. Koulun kerhotoiminta edistämässä valmistavan luokan oppilaiden integroitumista. Kasvatustieteen pro gradu -tutkielma. Jyväskylän yliopisto. Opettajankoulutuslaitos. 55 sivua. Tutkimuksen tehtävänä oli selvittää valmistavan luokan oppilaiden integroitumista perusopetuksen ryhmään yhteistoiminnallista oppimista ja kerhotoimintaa hyödyntäen. Tutkimus on laadullinen toimintatutkimus, joka toteutettiin Yhteisöllisyyttä kouluihin yhteisötaiteen keinoin -hankkeessa. Tutkimuksen tarkoituksena on edistää alakouluikäisten osallisuutta kouluyhteisössään. Tutkimuksen aineisto kerättiin osallistuvan havainnoinnin ja kerhonohjaajien (n=4) haastattelujen keinoin. Aineisto…

valmistava luokkamaahanmuuttajaoppilasyhteistoimintaintegraatioliikunnallinen kerhotoimintakerhotoimintaliikuntamaahanmuuttajatoppilaatvalmistava opetus
researchProduct

Discussions of Fatherhood in Male Batterer Treatment Group

2013

The aim of this study was to examine how men who have perpetrated violence toward their partners and participated in batterer group talked about being a father and how they perceived their own fatherhood. The discussion in the group was analyzed qualitatively by using the methods of content analysis. In traditional fatherhood, they talked about avoidant, passiveness, distant, indifference, and authoritative controlling ways of acting. These men also created an image of themselves as active and caring fathers, thus including empathy and nurture in the concept of fatherhood. This new fatherhood was considered an achieved goal and an objective for the men as being a father. Talking about fath…

vanhemmuusGeneral Arts and Humanitiesmedia_common.quotation_subjectlähisuhdeväkivaltaGeneral Social SciencesPoison controlHuman factors and ergonomicsEmpathybatterer groupfatherhoodSuicide preventionlcsh:History of scholarship and learning. The humanitiesNature versus nurtureTreatment and control groupslcsh:Social Scienceslcsh:Hpahoinpitelijöiden ohjelmaContent analysislcsh:AZ20-999Domestic violencePsychologySocial psychologyta515media_commonSAGE Open
researchProduct

Responsible fatherhood : a narrative approach

2015

vanhemmuusisyysvapaanarrativityparental responsibilitynarrative analysisisyysfirst-time fatherhoodperhe-elämäearly fatherhoodarkielämäperhevapaatmiestutkimusgendered parentingsukupuoliroolitmen's studieslastenhoitokäsityksetmiehetNarratiivinen tutkimusosallistuminen
researchProduct

"Tää on hauskaa puuhaa" : tutkiva toiminta varhaiskasvatuksen tiedekerhoissa

2016

Tutkimusten mukaan varhaislapsuudessa muodostuneet asenteet tiedekasvatuksesta vaikuttavat lasten tieteen oppimiseen myöhemmin. Tämän tutkimuksen tarkoitus oli selvittää, millaista on lasten tutkiva toiminta heille järjestetyissä tiedekerhoissa, ja mikä tutkimisessa innostaa lapsia. Tutkimuksen aineisto kerättiin yksityisessä päiväkodissa 5–6-vuotiaille lapsille järjestetyissä tiedekerhoissa. Kerhoissa oli 5 erilaista teemaa. Kerhokertoja oli 9 ja kerhoihin osallistui yhteensä 7 lasta. Tiedekerhot videoitiin ja videot litteroitiin tekstiksi. Aineisto analysoitiin laadullisesti. Tiedekerhoihin osallistuneet lapset olivat kiinnostuneita tutkimisesta. Lapset toivat esille, että tutkiminen oli …

varhaiskasvatustiedekasvatustutkiva oppiminenkerhotesiopetuslapset
researchProduct

Colour alone matters : no predator generalization among morphs of an aposematic moth

2018

Local warning colour polymorphism, frequently observed in aposematic organisms, is evolutionarily puzzling. This is because variation in aposematic signals is expected to be selected against due to predators' difficulties associating several signals with a given unprofitable prey. One possible explanation for the existence of such variation is predator generalization, which occurs when predators learn to avoid one form and consequently avoid other sufficiently similar forms, relaxing selection for monomorphic signals. We tested this hypothesis by exposing the three different colour morphs of the aposematic wood tiger moth, Arctia plantaginis, existing in Finland to local wild-caught predato…

varoitusväri0106 biological sciences0301 basic medicinepredatorspredator-prey interactionsoppiminengeneralisationta1172ZoologyAposematismBiologywarning coloration010603 evolutionary biology01 natural sciencestäpläsiilikäsgeneettinen monimuotoisuusPredationpolymorphism03 medical and health sciencesArctia plantaginisGeneralization (learning)petoeläimetmatkiminenmothsjäljittelyPredatorEcology Evolution Behavior and Systematicswood tigersaaliseläimetWinglearningCyanistesyöperhosetpredator–prey interactionswood tiger mothbiology.organism_classificationpredator generalization030104 developmental biologywarning signalsMimicryta1181Animal Science and ZoologypreyAnimal Behaviour
researchProduct

Transparency reduces predator detection in mimetic clearwing butterflies

2019

International audience; Predation is an important selective pressure and some prey have evolved conspicuous warning signals that advertise unpalatability (i.e. aposematism) as an antipredator defence. Conspicuous colour patterns have been shown effective as warning signals, by promoting predator learning and memory. Unexpectedly, some butterfly species from the unpalatable tribe Ithomiini possess transparent wings, a feature rare on land but common in water, known to reduce predator detection.We tested if transparency of butterfly wings was associated with decreased detectability by predators, by comparing four butterfly species exhibiting different degrees of transparency, ranging from ful…

varoitusväri0106 biological scienceskokeilubirdTransparency (market)perhosetaposematicZoologyAposematism010603 evolutionary biology01 natural sciencesPredationläpinäkyvyyscitizen sciencePredatorEcology Evolution Behavior and Systematicssuojaväri[SDV.EE]Life Sciences [q-bio]/Ecology environmentbiologyexperiment[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]vision modellingbiology.organism_classificationIthomiinicrypsisIthomiinidetectability[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate ZoologykansalaistiedeCrypsisButterflyMimicrymonarkkiperhoset010606 plant biology & botany
researchProduct

Predator-Induced Plasticity on Warning Signal and Larval Life-History Traits of the Aposematic Wood Tiger Moth, Arctia plantaginis

2021

Correction Frontiers in Ecology and Evolution Volume 9 Article Number 737651 DOI 10.3389/fevo.2021.737651 Published JUL 29 2021 Predator-induced plasticity in life-history and antipredator traits during the larval period has been extensively studied in organisms with complex life-histories. However, it is unclear whether different levels of predation could induce warning signals in aposematic organisms. Here, we investigated whether predator-simulated handling affects warning coloration and life-history traits in the aposematic wood tiger moth larva, Arctia plantaginis. As juveniles, a larger orange patch on an otherwise black body signifies a more efficient warning signal against predators…

varoitusväriREACTION NORMSperhosetcostsmelanizationcolorationtäpläsiilikästoukatlarvaddc:570PHENOTYPIC PLASTICITYBENEFITSCOLORaposematismFORAGING BEHAVIORplastic responseRISKsopeutuminenfungiMELANIZATIONEVOLUTIONsaalistusmaladaptationLepidopteraelinkiertoTRADE-OFF1181 Ecology evolutionary biologyfenotyyppi
researchProduct