Search results for "Riba"
showing 10 items of 371 documents
The optimal dose of ribavirin for chronic hepatitis C: From literature evidence to clinical practice: The optimal dose of ribavirin for chronic hepat…
2010
Approximately 170 million people worldwide are chronically infected by hepatitis C virus (HCV), which can result in progressive hepatic injury and fibrosis, culminating in cirrhosis and end-stage liver disease. The benchmark therapy for untreated HCV patients is a combination of pegylated interferon-alpha (PEG-IFN) and ribavirin (RBV). Several studies have suggested several potential new approaches to improve HCV therapy-optimization of the dose and duration of RBV therapy, accompanied by careful clinical management, is crucial in ensuring the greatest likelihood of a long response to therapy. RBV causes serious side effects, but in clinical practice, there are no alternatives for the treat…
Aging on Indian Reservations: The Ugly, the Bad, and the Good
2012
This chapter examines the conditions for the older population on Indian reservations and how those conditions compare to the non-Indian population. The discussion opens on a national level, though the focus is on tribes in the Western United States. Older Indians on reservations are aging in a society where they are an almost invisible part of rural America. Yet the reservations, despite the poor socioeconomic conditions on many, represent home and a place for off-reservation Native Americans to come back to. To include the voices of Indian elders and gain insights into how they perceive being elders, we report on interviews conducted with older Indians on the Nez Perce reservation in Idaho…
FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin…
2011
Background & Aims EPIC-3 is a prospective, international study that has demonstrated the efficacy of PEG-IFN alfa-2b plus weight-based ribavirin in patients with chronic hepatitis C and significant fibrosis who previously failed any interferon–alfa/ribavirin therapy. The aim of the present study was to assess FibroTest (FT), a validated non-invasive marker of fibrosis in treatment-naive patients, as a possible alternative to biopsy as the baseline predictor of subsequent early virologic (EVR) and sustained virologic response (SVR) in previously treated patients. Methods Of 2312 patients enrolled, 1459 had an available baseline FT, biopsy, and complete data. Uni- (UV) and multi-variable (MV)…
Četrgadīgu bērnu ar kreilību psihiskās attīstības sekmēšana vizuālās mākslas nodarbībās pirmsskolā
2022
Darba autore ir Diāna Petrova. Bakalaura darba tēma: Četrgadīgu bērnu ar kreilību psihiskās attīstības sekmēšana vizuālās mākslas nodarbībās pirmsskolā. Bakalaura darba vadītāja ir asoc. prof., Mg. art., Dr. paed. Ilze Briška. Darba mērķis ir pētīt četrgadīgu bērnu ar kreilību psihisko attīstību vizuālās mākslas nodarbībās pirmsskolas izglītības iestādē. Bakalaura darbs sastāv no ievada, divām darba daļām un 8 apakšdaļām, 15 attēliem, 4 tabulām, 8 secinājumiem, 7 priekšlikumiem, 45 literatūras avotiem, 7 pielikumiem. Kopējais darba apjoms 64 lappuses. Darba teorētiskajā daļā ir analizēta teorētiskā un metodiskā literatūra par pirmsskolas bērnu psihisko procesu attīstību, par kreilību. To sk…
Los notarios y su documentación. Diplomática notarial valenciana
2023
Las nuevas orientaciones de la Diplomática no solo han ampliado su campo de estudio más allá de las cancillerías reales y la pontificia con el análisis de la documentación de otras escribanías, entre ellas las notariales, sino que han introducido un nuevo enfoque: la contextualización del documento dentro de la sociedad en la que se produce. La presente monografía parte del estudio de los colegios notariales valencianos en la época foral, del análisis de la práctica notarial y de la prosopografía de los notarios durante los reinados de Pedro IV, Juan I y Martín el Humano, época de consolidación de la ‘auctoritas’ del notario, para profundizar en el estudio de los notarios apostólicos y, esp…
Nueva era en el combate contra el cáncer: Evolución y cáncer: progreso y tratamiento de tumores
2013
L’oncohematologia ha assistit en les últimes dècades a importants avenços en el tractament i supervivència. La toxicitat derivada de la quimioteràpia clàssica i la necessitat de millorar l’eficàcia i tolerància als tractaments han fet que es desencadene un allau d’activitat investigadora que constantment proporciona fruits. Gran part d’aquest esforç s’ha enfocat al desenvolupament de «teràpies diana» dirigides contra determinades alteracions funcionals, clau per a la supervivència de la cèl·lula tumoral. Així es pretén aconseguir major eficàcia en el tractament i que el pacient pague un menor cost en toxicitat. Avenços en altres disciplines de l’oncologia com l’epidemiologia, la cirurgia i …
The King’s Lace Bug Recaredus rex Distant, 1909 (Hemiptera: Heteroptera: Tingidae): Systematic Position, First Palaearctic and Afrotropical Rec…
2022
The systematic position and actual distribution of Recaredus rex, for a long time one of the most enigmatic lace bug genus and species, is very obscure because only the type specimen and three other individuals from India are known to date. In the present paper, we report the first records of R. rex from the Palaearctic region (Iran) and tropical Africa (Ghana). Based on the occurrence localities and climatic variables, we predict potentially useful ecological niches for this species using Maxent software. The areas with the best environmental conditions for R. rex indicated in our studies suggest its possible Palaeotropical distribution. Moreover, we regard these results as a good starting…
Ptyctima (Acari, Oribatida) in various habitats in Finland
2010
The oribatid species of the taxon Ptyctima were studied in eight habitat types (four forests, three bogs, and one shore). Altogether 19 species were found. The highest number of species (15) was found in marsh forests in southern Finland, and the lowest number (3) in eutrophic fens in northern Finland. Atropacarus striculus was the most common and abundant species in Finland. It was found in each habitat explored, especially abundant on shores, in marsh forests, and pine bogs. Phthiracarus longulus, P. boresetosus, and Steganacarus carinatus occurred in abundance in coniferous forests, especially in the southern and central parts of the country, whereas Rhysotritia ardua was found there onl…
A Novel Approach to Identify Candidate Prognostic Factors for Hepatitis C Treatment Response Integrating Clinical and Viral Genetic Data
2015
The combined therapy of pegylated interferon (IFN) plus ribavirin (RBV) has been for a long time the standard treatment for patients infected with hepatitis C virus (HCV). In the case of genotype 1, only 38%–48% of patients have a positive response to the combined treatment. In previous studies, viral genetic information has been occasionally included as a predictor. Here, we consider viral genetic variation in addition to 11 clinical and 19 viral populations and evolutionary parameters to identify candidate baseline prognostic factors that could be involved in the treatment outcome. We obtained potential prognostic models for HCV subtypes la and lb in combination as well as separately. We …
Validación del sistema de detección precoz de trastornos del desarrollo (SDPTD): 0 a 12 meses
2014
Se ha realizado un análisis de los sistemas de detección más conocidos, clasificándolos según el área que evalúan como, específicos (cuando detectan un tipo de trastorno concreto) y generales, cuando evalúan el desarrollo en general. Además también existen otros sistemas que tratan de detectar trastornos específicos en áreas concretas del desarrollo, como por ejemplo el lenguaje, la comunicación, el desarrollo socio-emocional, etc. Por otra parte, se ha analizado la forma de administración y aunque lo general es que los cuestionarios sean administrados por profesionales, existe una tendencia a construir cuestionarios o sistemas basados en la respuesta de los padres. Este tipo de cuestionari…