Search results for "Rill"

Astrocytes give rise to new neurons in the adult mammalian hippocampus

2001

Neurogenesis in the dentate gyrus of the hippocampus persists throughout life in many vertebrates, including humans. The progenitors of these new neurons reside in the subgranular layer (SGL) of the dentate gyrus. Although stem cells that can self-renew and generate new neurons and glia have been cultured from the adult mammalian hippocampus, the in vivo primary precursors for the formation of new neurons have not been identified. Here we show that SGL cells, which express glial fibrillary acidic protein and have the characteristics of astrocytes, divide and generate new neurons under normal conditions or after the chemical removal of actively dividing cells. We also describe a population o…

Analysis of NO synthase expression in neuronal, astroglial and fibroblast-like derivatives differen-tiating from PCC7-Mzl embryonic carcinoma cells

1999

We studied the expression of the NO synthase isoforms in an in vitro model of neural development using RT-PCR, Western blot and immu- nohistochemistry. Murine PCC7-Mzl cells (Jostock et al., Eur. J. Cell Biol. 76, 63–76,1998) differentiate in the presence of all-trans retinoic acid and dibutyryl cAMP along the neural pathway into neuron-like, fibroblast-like and astroglia-like cells. Undifferentiated cells showed immunofluorescent staining for neuronal-type NOSI and endothelial- type NOS III. This expression pattern was retained in those cells differ entiating into neurofilament- and tau protein-positive neuronal cells. Thymocyte alloantigen (Thyl.2/CD 90.2)-positive Fibroblasts, appearing …

Interpretation of EXAFS in ReO3using molecular dynamics simulations

2009

Temperature dependent Re L3-edge EXAFS signals from perovskite-type cubic ReO3 have been successfully interpreted using a combination of classical NVT molecular dynamics (MD) and ab initio multiple-scattering approach. The force field model, required for MD simulations, has been determined by fitting the Re-O and O-O pairwise interatomic potentials to a set of experimental data (lattice parameter, elastic constants and bulk modulus) and phonon frequencies, theoretically calculated from the first principles at high symmetry points of the Brillouin zone. The MD simulations reproduce well the anisotropy of thermal vibration for oxygen atoms and confirm a deviation of the mean Re-O-Re angle fro…

Administración liberal y corrupción política: el conflicto del Real Colegio de San Pablo con el Instituto Provincial de Valencia

2015

The present paper examines the Spanish public schools inside the liberal educative system doing a detailed analysis of the Real Colegio de San Pablo of Valencia. The article studies this Real Colegio in order to point out the conflict provoked by political corruption, since Juan Bravo Murillo, a Spanish minister, appointed relatives to direction posts against the desires of Antonio Gil de Zárate, the founder of the Spanish liberal educative system. In this case, the struggle between personal interest of politicians and the necessities of the new and modern administration were related to the problematic issue of the model of high schools established by the State: elitist public schools or op…

Alexander Keese. Ethnicity and the Colonial State. Finding and Representing Group Identifications in a Coastal West African and Global Perspective (1…

2017

A new calculation procedure for non-uniform residual stress analysis by the hole-drilling method

1998

The hole-drilling method is one of the most used semi-destructive techniques for residual stress analysis in mechanical parts. In the presence of non-uniform residual stress, the stress field can be determined from the measured relaxed strains using several calculation methods, but the most used one is the so-called integral method. This method is characterized by some simplifications that lead to approximate results, especially when the residual stress varies abruptly. In this paper a new calculation procedure called the spline methods is proposed, which allows these drawbacks to be overcome. Numerical simulations and an experimental test have corroborated the best performance of the prop…

Measurement of residual stresses by the hole-drilling method: Influence of hole eccentricity

1979

The hole-drilling method is a semidestructive technique which allows the measurement of residual stresses. In this method, a source of error is due to the misalignment between the hole and rosette centres. This paper presents a theoretical analysis of the influence of such misalignment on the strains measured by the rosette. Formulae which give the residual stresses taking account of the hole eccentricity are derived. Finally, the errors, which affect the residual stresses when the eccentricity is neglected, are evaluated for some commercial strain-gauge rosettes especially developed for the hole-drilling method.

Error and Uncertainty Analysis of the Residual Stresses Computed by Using the Hole Drilling Method

2010

:  The hole-drilling method is one of the most used techniques for the experimental analysis of the residual stresses in mechanical components. For both through-thickness uniform and non-uniform residual stress distributions, its application is standardised by the ASTM E837-08. In accordance with the ASTM limitations, the analysis of uniform residual stresses, to which the present work deals with, leads in general to results with a maximum bias of about 10%. Unfortunately, in general the user does not have appropriate procedures to estimate the actual stress error; consequently, if one or more of the experimental influence parameters fall out of the corresponding standard limitations, the c…

A New Procedure for the Evaluation of Non-Uniform Residual Stresses by the Hole Drilling Method Based on the Newton-Raphson Technique

2010

The hole drilling method is one of the most used semi-destructive techniques for the analysis of residual stresses in mechanical components. The non-uniform stresses are evaluated by solving an integral equation in which the strains relieved by drilling a hole are introduced. In this paper a new calculation procedure, based on the Newton-Raphson method for the determination of zeroes of functions, is presented. This technique allows the user to introduce complex and effective forms of stress functions for the solution of the problem. All the relationships needed for the evaluation of the stresses are obtained in explicit form, eliminating the need to use additional mathematical tools. The t…

Review of Some Development of the Hole Drilling Method

1990

This paper contains a survey of some developments of the hole drilling method. It is mainly based on the research work carried out at the University of Palermo in the years from 1978 to 1989. The paper considers the relationship between the relaxed strain and the residual stresses for a rosette with an off-centre hole, the influence of hole eccentricity on the determination of residual stresses and of rosette calibration constants, the sensitivity of strain relaxation.