Search results for "Rimi"
showing 10 items of 3981 documents
Recenzja: J. Widacki, A. Szuba-Boroń, Sprawy o szpiegostwo przed sądami wileńskimi w okresie II RP. Przyczynek do historii zmagań polskiego wywiadu i…
2021
Problematyka badawcza, którą podjęli J. Widacki i A. Szuba-Boroń nie była dotąd przedmiotem zainteresowań naukowych. Jan Widacki podczas sprawowania misji dyplomatycznej w Wilnie kontynuował swoje zainteresowania naukowe, docierając do akt spraw o szpiegostwo z okresu międzywojennego. Natomiast Anna Szuba- -Boroń badając m.in. akta spraw o szpiegostwo zajęła się prozą Sergiusza Piaseckiego, pisarza i byłego szpiega. Obraz pogranicza, a w nim walka wywiadów sowieckiego, litewskiego oraz polskiego kontrwywiadu to niewątpliwie interesujące tło do ba-dań. Autorzy zdają sobie sprawę z ograniczeń badawczych, nie dotarli bowiem do spraw sądzonych w innych sądach okręgowych znajdujących się na tere…
Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
2020
ABSTRACT Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeutic cancer vaccine, which is based on a liposomal formulation of tumor-antigen encoding RNA (RNA-LPX) and induces a strong T-cell response both in mice as well as in humans. In this study, we investigated in vivo in mice and in human PBMCs the effect of the commonly used long-acting GCS Dexamethasone (Dexa) on the efficacy of this vaccine format, with a particular focus on antigen-specif…
How many longitudinal covariate measurements are needed for risk prediction?
2014
Abstract Objective In epidemiologic follow-up studies, many key covariates, such as smoking, use of medication, blood pressure, and cholesterol, are time varying. Because of practical and financial limitations, time-varying covariates cannot be measured continuously, but only at certain prespecified time points. We study how the number of these longitudinal measurements can be chosen cost-efficiently by evaluating the usefulness of the measurements for risk prediction. Study Design and Setting The usefulness is addressed by measuring the improvement in model discrimination between models using different amounts of longitudinal information. We use simulated follow-up data and the data from t…
Acoustic detection and classification of river boats
2011
We present a robust algorithm to detect the arrival of a boat of a certain type when other background noises are present. It is done via the analysis of its acoustic signature against an existing database of recorded and processed acoustic signals. We characterize the signals by the distribution of their energies among blocks of wavelet packet coefficients. To derive the acoustic signature of the boat of interest, we use the Best Discriminant Basis method. The decision is made by combining the answers from the Linear Discriminant Analysis (LDA) classifier and from the Classification and Regression Trees (CART) that is also accompanied with an additional unit, called Aisles, that reduces fal…
Government policy failure in public support for research and development
2014
peer-reviewed Promoting Research and Development (R&D) and innovative activity is a key element of the EU Lisbon Agenda and is seen as playing a central part in stimulating economic development. In this paper we argue that, even allowing for benevolent policy-makers, informational asymmetries can lead to a misallocation of public support for R&D, hence government policy failure, with the potential to exacerbate preexisting market failures. Initially, we explore alternative allocation mechanisms for public support, which can help to minimize the scale of these government policy failures. Of these mechanisms (grants, tax credits, or allocation rules based on past performance), our results sug…
Diversity begets diversity: A global perspective on gender equality in scientific society leadership.
2018
Research shows that gender inequality is still a major issue in academic science, yet academic societies may serve as underappreciated and effective avenues for promoting female leadership. That is, society membership is often self-selective, and board positions are elected (with a high turnover compared to institutions)—these characteristics, among others, may thus create an environment conducive to gender equality. We therefore investigate this potential using an information-theoretic approach to quantify gender equality (male:female ratios) in zoology society boards around the world. We compare alternative models to analyze how society characteristics might predict or correlate with the …
Gender segregation in the employment of higher education graduates
2014
This article examines the employment and placement in the working life of Finnish higher education graduates (i.e. graduates from universities and polytechnics), focusing on gender equality. It reports a study on gender segregation in higher education and working life, considered in relation to Nordic gender equality policies. The data were gathered via a questionnaire administered to graduates in business and administration (n = 1067) and in technology (n = 1087), three years after their graduation. The results showed that men were able to secure permanent and full-time employment more often than women, and men achieved better correspondence between their degree and their employment. Howev…
El crimen de agresión : ¿es posible su persecución judicial internacional?
2021
The paper analyses the crime of aggression, in particular the recent activation of the jurisdiction of the International Criminal Court over it and the main obstacles to its effective prosecution, taking into consideration the low number of States Parties that have ratified the Amendments that regulate it
Taktisko paņēmienu izmantošana un ar to sistītas problēmas pratināšanā
2015
Kriminālprocesa likuma 10.nodaļā ir nosaukti izmeklēšanas darbību veidi un to būtība. Viena no šīm izmeklēšanas darbībām ir pratināšana, tās definīcija ir noteikta Kriminālprocesa likuma 145.pantā. Kriminālprocesa likums nesniedz priekšstatu par pratināšanas nozīmīgumu un pratināšanas norises kārtību. Tas ir atrodams kriminālistikas un kriminālprocesa literatūrā un doktrīnā. Pašu pratināšanas kārtību un tās norisi nosaka procesa virzītājs. Lai efektīvi spētu izmantot pratināšanai paredzēto laiku un noskaidrotu no pratināmās personas patiesu informāciju, procesa virzītājam ir jāizmanto taktiskie paņēmieni, ar mērķi padarīt pratināmās personas vēlmi sniegt nepatiesas ziņas par neiespējamu. Ta…
Notikuma vietas apskates taktiskie paņēmieni
2017
Notikuma vietas apskate ir viena no sarežģītākajām izmeklēšanas darbībām ne tikai tādēļ, ka iespējams iegūt plaša apjoma informāciju, bet arī tādēļ, ka, pievēršot uzmanību kādam konkrētam objektam, nepamanāms var kļūt kāds cits izmeklējamā lietā nozīmīgs objekts. Tieši tādēļ nepieciešams ievērot atbilstošus taktiskos paņēmienus, lai būtiskais tiktu pamanīts un fiksēts, kā arī lai efektīvāk, ātrāk, bet tajā pašā laikā kvalitatīvāk norisinātos apskate. Lai sasniegtu darbā izvirzītos mērķus, darba autore analizē taktiskos paņēmienus katrā notikuma vietas apskates stadijā, pēta tiesu praksi un veic aptauju. Darba izstrādes laikā autore secina, ka taktiskais paņēmiens ir neatņemams notikuma viet…