Search results for "Rimonabant"

showing 1 items of 31 documents

2021

White adipose tissue (WAT) possesses the endocannabinoid system (ECS) machinery and produces the two major endocannabinoids (ECs), arachidonoylethanolamide (AEA) and 2-arachidonoylglycerol (2-AG). Accumulating evidence indicates that WAT cannabinoid 1 receptors (CB1R) are involved in the regulation of fat storage, tissue remodeling and secretory functions but their role in controlling lipid mobilization is unclear. In the present study, we used different strategies to acutely increase ECS activity in WAT and tested the consequences on glycerol production as a marker of lipolysis. Treating lean mice or rat WAT explants with JLZ195, which inhibits ECs degrading enzymes, induced an increase in…

medicine.medical_specialtyChemistryEndocrinology Diabetes and Metabolismmedicine.medical_treatmentAdipose tissueStimulationWhite adipose tissueEndocannabinoid systemEndocrinologyRimonabantInternal medicinemedicineLipolysislipids (amino acids peptides and proteins)CannabinoidReceptormedicine.drugFrontiers in Endocrinology

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PEPhysical Sciences and Engineering
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