Search results for "Rini"

showing 10 items of 746 documents

Stimulatory and inhibitory effects of ethanol on hippocampal acetylcholine release

1998

Using the microdialysis technique and sensitive HPLC procedures for the determination of acetylcholine (ACh) and ethanol, we investigated the release of ACh in rat hippocampus after acute ethanol administration. Systemic administration of ethanol (0.8 and 2.4 g/kg i.p.) led to peak ethanol concentrations of 21 and 42 mM in the hippocampus, respectively. The high dose caused a long-lasting inhibition of basal ACh release by up to 33%. Local infusion of scopolamine (1 microM) enhanced hippocampal ACh release up to eightfold in the presence of neostigmine (10 microM), and this stimulated release was also inhibited after systemic ethanol administration (by up to 45%). The low dose of ethanol (0…

MaleMicrodialysisMicrodialysisScopolamineHippocampusStimulationMuscarinic AntagonistsHippocampal formationPharmacologyHippocampuschemistry.chemical_compoundmedicineAnimalsRats WistarChromatography High Pressure LiquidPharmacologyEthanolEthanolCentral Nervous System DepressantsGeneral MedicineAcetylcholineRatsKineticschemistrySystemic administrationCholinergicExtracellular SpaceAcetylcholinemedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

2015

Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression or activity, including gene transcription to RNA followed by translation to the protein level, by transcription factors (e.g. NF-κB, HIF-1α) and mRNA binding proteins (e.g. GAPDH, HuR) is subject to redox regulation. This review will give an update of recent discoveries in this field, and specifically highlight the impact of reactive oxygen and nitrogen species on DNA repair systems that contribute to genomic stability. Emphasis will be placed …

Genome instabilityRedox signalingRNA UntranslatedEpigenetic regulation of neurogenesisDNA RepairHuR mRNA-binding protein in the 3′-untranslated regionClinical BiochemistryHDAC histone deacetylaseReview ArticleAP-1 activator protein 1BiochemistryApe-1 apurinic/apyrimidinic endonuclease 1GPx-1 glutathione peroxidase-1Epigenesis GeneticHistonesTrx thioredoxinPHD prolylhydroxylaseBER base excision repairlcsh:QH301-705.5HO-1 heme oxygenase-1EpigenomicsGeneticsRegulation of gene expressionNox member of the NADPH oxidase familylcsh:R5-920JmjC Jumonji C domain-containing histone demethylasesHIF-1α hypoxia inducible factor-1α5-hmC 5-hydroxymethylcytosineddc:Cell biologyMMP matrix metalloproteinaseGrx glutaredoxinGAPDH glyceraldehyde-3-phosphate dehydrogenaseNrf2 nuclear factor erythroid related factor 2DNA methylationEpigeneticslcsh:Medicine (General)Oxidation-ReductionSignal Transduction5-mC 5-methylcytosineDNA repairDNA damageNF-κB nuclear factor-κBBiologyGenomic InstabilityRNS reactive nitrogen speciesROS reactive oxygen speciesNER nucleotide excision repairSOD superoxide dismutaseOxyR transcription factor (hydrogen peroxide-inducible genes activator)HumansEpigeneticsOrganic ChemistryPETN pentaerithrityl tetranitrateGene regulationOxidative StressDNMT DNA methyltransferaseGene Expression Regulationlcsh:Biology (General)AREs AU-rich elementsHAT histone acetyltransferaseKeap1 kelch-like ECH-associated protein 1BiomarkersCOPD chronic obstructive pulmonary disorderDNA DamageRedox Biology
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De S. Trinitate libri tres contra huius aeui Trinitarios, Antitrinitarios, [et] Autotheanos / G. Genebrardo ... auctore ...

1569

Sig. a8, A-V8, X4 Capitals grav. - Fris Text amb postil·les marginals. - Reclams al final de cada quadern

Teologia dogmàtica Obres anteriors a 1800Trinitat Obres anteriors a 1800DIG-BHPolèmiques teològiques Obres anteriors al 1800
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Locust neuropeptides stimulating sex pheromone production in female European corn borer moth, Ostrinia nubilalis

1990

Abstract The presence of a pheromonotropically active hormone (PBAN-like substance) from locust organs, ( Locusta migratoria ) has been demonstrated. Extracts of brain, corpora cardiaca, corpora allata, suboesophageal ganglia and thoracic ganglia of L. migratoria caused highly pheromonotropic responses in decapitated females of the European corn borer moth ( Ostrinia nubilalis ). The highest activity per unit weight of tissue was found in the corpora cardiaca and corpora allata of the locust followed by the brain plus suboesophageal ganglion of O. nubilalis . Following 8 days of disconnection, separating the corpora allata from the corpora cardiaca and suboesophageal ganglion, the pheromono…

endocrine systemmedicine.medical_specialtyEuropean corn borerbiologyurogenital systemPhysiologybiology.organism_classificationOstriniaAcrididaeEndocrinologymedicine.anatomical_structureInsect ScienceInternal medicineSex pheromonemedicineSuboesophageal ganglionCorpus allatumThoracic gangliahormones hormone substitutes and hormone antagonistsreproductive and urinary physiologyLocustJournal of Insect Physiology
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Fish introductions and light modulate food web fluxes in tropical streams : a whole-ecosystem experimental approach

2016

Decades of ecological study have demonstrated the importance of top-down and bottom-up controls on food webs, yet few studies within this context have quantified the magnitude of energy and material fluxes at the whole-ecosystem scale. We examined top-down and bottom-up effects on food web fluxes using a field experiment that manipulated the presence of a consumer, the Trinidadian guppy Poecilia reticulata, and the production of basal resources by thinning the riparian forest canopy to increase incident light. To gauge the effects of these reach-scale manipulations on food web fluxes, we used a nitrogen (15N) stable isotope tracer to compare basal resource treatments (thinned canopy vs. con…

stable isotope tracersNeotropics15Nnitrogen fluxtrophic linkagesstream food webTrinidad guppytop-down and bottom-up effectsbenthic macroinvertebratesalkutuotantoreach-scale experiment
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Long-Term Management of Overactive Bladder with Antimuscarinic Agents

2007

Abstract Antimuscarinic therapy is the primary treatment for overactive bladder. Long-term persistence with the therapy can be problematical, and has been linked to both efficacy and tolerability. A number of specific contributory factors to poor persistence can be identified, such as adverse effects of medication, insufficient beneficial effects, inadequate follow-up after initiation of therapy (poor motivation), and unmet or unrealistic expectations (poor communication between the patient and physician). Open-label studies on antimuscarinics overestimate the real-life persistence, which can lead to unrealistic expectations of the physician. Dose flexibility has improved patient compliance…

medicine.medical_specialtyAntimuscarinic Agentbusiness.industryTransdermal patchUrologymedicine.diseasePatient satisfactionTolerabilityQuality of lifeOveractive bladderPillPhysical therapyMedicineAdverse effectbusinessIntensive care medicineEuropean Urology Supplements
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Factors affecting between-lake variation in the occurrence of epidermal papillomatosis in roach,Rutilus rutilus(L.)

2009

The theory of island biogeography predicts that the probability of a species occupying an island depends on a dynamic equilibrium between extinction and colonization. Epidermal papillomatosis is a disease manifesting as skin tumours on fish. We studied the factors affecting the occurrence of the disease in roach, Rutilus rutilus (L.), in 34 lakes. The results of discrimination analysis suggest that maximum depth, percentage of the drainage area of the lake covered by lakes in the vicinity and altitude best identified diseased lakes. Comparison of diseased and non-diseased lakes revealed that lake area could also be regarded as a variable contributing to the occurrence of the disease. The sa…

MaleInsular biogeographyVeterinary (miscellaneous)BiogeographyCyprinidaeDrainage basinFresh WaterAquatic ScienceFish DiseasesAltitudeRisk Factorsparasitic diseasesAnimalsColonizationAnalysis of Variancegeographygeography.geographical_feature_categoryExtinctionPapillomabiologyEcologyDiscriminant AnalysisAquatic animalbiology.organism_classificationSkin Diseases ViralFemaleRutilusJournal of Fish Diseases
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Bernoullin luvut ja Euler-MacLaurinin summakaava

2007

Bernoullin luvutEulerin summakaavaBernoullin polynomitEuler-MacLaurinin summakaava
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Fish community structure in mesotrophic and eutrophic lakes of southern Finland: the relative abundances of percids and cyprinids along a trophic gra…

2002

In 36 south Finnish lakes, the number of species, as well as the cyprinids:percids ratio, was dependent, not only on total phosphorus (TP), but also on lake size. Total fish biomass and cyprinid biomass increased along the TP gradient, whereas the dependence of percid biomass was less evident. Perch Perca fluviatilis and roach Rutilus rutilus strongly dominated mesotrophic lakes; in eutrophic lakes the proportion of other cyprinids and percids, such as white bream Blicca bjoerkna, bream Abramis brama, pikeperch Stizostedion lucioperca and ruffe Gymnocephalus cernuus, increased. Perch biomass was weakly related to abiotic factors but depended on roach biomass. Lake size and fish species comp…

0106 biological sciencesBiomass (ecology)PerchBiomanipulationbiologyStizostedion luciopercaEcology010604 marine biology & hydrobiologyAquatic Sciencebiology.organism_classification010603 evolutionary biology01 natural sciencesPercidaeCyprinidae14. Life underwaterRutilusGymnocephalusEcology Evolution Behavior and SystematicsJournal of Fish Biology
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The chemical composition of the aerial parts essential oil of Ammi crinitum Guss. (Apiaceae) endemic of Sicily (Italy)

2022

Ammi L. is a small genus of economically important plants belonging to Apiaceae family that includes only six taxa. In the present study the chemical composition of the essential oil from aerial parts of Ammi crinitum Guss., a very rare plant, endemic of Sicily, was analyzed by GC–MS. No previously paper has been published on this species. The results showed the presence of large quantity of monoterpene hydrocarbons with sabinene (63.9%), as the most abundant component. Other metabolites present in good quantity were γ-terpinene (8.0%), and 4-terpineol (3.7%). Based on the composition of the essential oil of all the other Ammi taxa, several considerations have been carried out.

sabineneOrganic ChemistryapiaceaePlant Scienceessential oilsBiochemistryAmmi crinitum GussAnalytical ChemistryNatural Product Research
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