Search results for "Risk Analysi"

Theoretical and Practical Fundamentals

2014

Project managers carry out a project with several objectives in mind. They want to finish the project as soon as possible, with the minimum cost, the maximum quality, etc. This chapter studies project scheduling problems when several goals are sought, that is, multi-objective project scheduling problems (MOPSPs) and multi-objective resource-constrained project scheduling problems (MORCPSPs). We will discuss some of the most important issues that have to be taken into account when dealing with these problems. We will also prove some useful results that can help researchers create algorithms for some of these problems.

Avoiding Demand Amplification Phenomenon via Hi-tech Application: A What-If Supply Chain Analysis

2010

The well-known deleterious effect of the amplification of variance of order rates in multi-echelon systems, commonly known as demand amplification phenomenon or bullwhip effect, still presents new challenges and continues to fascinate the operations management community. Recently this research field is focusing on the study of robustness of bullwhip avoidance techniques under uncertainty, as environmental conditions often determine variations in processes, with regards to production and delivery lead time, and variations in the parameters of the decision policies. This work aims at quantifying the efficacy of bullwhip dampening techniques and at verifying this efficacy against variations in…

New Directions for Use of Systemic Drug Delivery in Anti-aging Medicine

2020

Abstract Anti-aging medicine has become a popular topic in recent years. It considers biological aging a revertible process that physiologically serves no posi tive function. Different technologies in systemic delivery and various strategies that characterize and optimize the performance of systemic delivery have been covered in this book. These technologies are essential for the establishment of a technical platform for interventive biogerontology. As the last chapter of this book, we would like to highlight some directions for future applications of systemic drug delivery in anti-aging medicine. We believe that biological aging and aging-related diseases are strongly associated with genet…

Fuzzy approach based model of interrelated factors for financial industry client risk assessment

2020

Risk Assessment of Physical Security within a Technologized Knowledge Based Organization

2019

The purpose of this scientific paper is to support the decisionmaking process on the risk management based on the results of an analysis and subsequently on the risks hierarchy. This assessment involves the comparison of the level of risk determined by the analysis with the risk criteria developed in the context of the establishment phase. This scientific paper on assessing and treating risks to physical security has been developed to identify, assess and quantify the associated risk in a technologizedknowledge-based organization. The basis of this study on the assessment and treatment of risks to physical security is to identify specific potential risks as well as the emergency response pr…

Selecting the best risk measure in multiobjective cash management

2018

What does insurance purchase behaviour say about risks?

2015

Purpose – This paper aims to explore the world of insurances as rites of adaptancy and resiliency before risk and disasters. The research on risks, both perceived and real, has become a frequent theme of academic research in the recent past. Design/methodology/approach – The information given by the superintendencia de Seguros de Buenos Aires involves 100 per cent of the insurances companies of Argentina. The reading of insurance demands corresponds with a new method in the studies of risks. Findings – Using advanced probability theory and quantitative techniques, risk management researchers have been able to construct sophisticated mathematical-statistical models of risk. Research limitat…

Contribution of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: the MONICA, risk, genetics, archiving, and monograph…

2010

Background— Cardiovascular risk estimation by novel biomarkers needs assessment in disease-free population cohorts, followed up for incident cardiovascular events, assaying the serum and plasma archived at baseline. We report results from 2 cohorts in such a continuing study. Methods and Results— Thirty novel biomarkers from different pathophysiological pathways were evaluated in 7915 men and women of the FINRISK97 population cohort with 538 incident cardiovascular events at 10 years (fatal or nonfatal coronary or stroke events), from which a biomarker score was developed and then validated in the 2551 men of the Belfast Prospective Epidemiological Study of Myocardial Infarction (PRIME) co…

Expectations and forward risk premium in the Spanish deregulated power market

2010

Abstract Deregulation in energy markets has entailed important changes in the way agents conduct business. Price risk arises as a result of fluctuations in the future price of electricity and agents assume long or short positions in the forward and spot markets to hedge their exposure to price risk. The presence of forward risk premium in prices is evidence of the fact that agents act in the market according to risk considerations. This work aims to analyse the information content of the difference between the forward and spot prices (the so-called forward premium) regarding the agents’ decisions. We find that the sign and magnitude of the ex post forward premium depend on the unexpected va…

A Quality Risk Management Model Approach for Cell Therapy Manufacturing

2010

International regulatory authorities view risk management as an essential production need for the development of innovative, somatic cell-based therapies in regenerative medicine. The available risk management guidelines, however, provide little guidance on specific risk analysis approaches and procedures applicable in clinical cell therapy manufacturing. This raises a number of problems. Cell manufacturing is a poorly automated process, prone to operator-introduced variations, and affected by heterogeneity of the processed organs/tissues and lot-dependent variability of reagent (e.g., collagenase) efficiency. In this study, the principal challenges faced in a cell-based product manufacturi…