Search results for "Risk Analysis"
showing 10 items of 375 documents
Safer chemicals using less animals: kick-off of the European ONTOX project
2021
The 3Rs concept, calling for replacement, reduction and refinement of animal experimentation, is receiving increasing attention around the world, and has found its way to legislation, in particular in the European Union. This is aligned by continuing high-level efforts of the European Commission to support development and implementation of 3Rs methods. In this respect, the European project called "ONTOX: ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessment" was recently initiated with the goal to provide a functional and sustainable solution for advancing human risk assessment of chemicals without the use of animal…
The Black-Litterman model
2013
Masteroppgave i økonomi og administrasjon - Universitetet i Agder 2013 The Markowitz model has two problematic tendencies; unintuitive portfolios and portfolios with high transaction costs. The Black-Litterman model was made as an improvement of the Markowitz model. It uses a Bayesian approach to combine the views of the investor with the equilibrium portfolio. The main purpose of the model is to create intuitive portfolios and limit the transaction costs. With the computer power available today, the implementation of mathematical models are an important issue. Using the programming language R, I will in this thesis look at possible ways of implementing the Black-Litterman model. Todays inv…
The performance of Value-at-Risk models on the OBX index
2013
Masteroppgave i økonomi og administrasjon - Universitetet i Agder 2013 The measuring of risk has become one of the main fields in finance during the last two decades. Value-at-Risk (VaR) has become one of the most important risk measures and is widely used for numerous applications. This thesis compares different approaches to VaR based on traditional methods such as Historical Simulation, Moving Average and Exponentially Weighted Moving Average as well as advanced approaches based on GARCH models. Comparison is done on the OBX index return data, which is the main benchmark index on the Oslo Stock Exchange. The performance of the different VaR models is evaluated with out of sample backtest…
Recent trends in rapid detection of influenza infections by bio and nanobiosensor
2018
Abstract A literature update has been made about the progress and improvements in the use of biosensors for sensitive, rapid and specific detection of influenza virus. Background information about influenza virus and its structure together with a general discussion about the characteristics and significant aspects of different types of biosensors were used as a frame to put inside the main recent developments on the use of nanobiosensors for the detection of influenza virus. Working criteria of biosensors and their applications in different species of influenza virus diagnosis have been the primary concern of this review, which critically discusses the main advantages and limitations of stu…
Principles and Elements of Risk Management – Data and Initial Conditions
2014
This chapter is devoted to furnishing background information on Risk Management, explaining the string of steps that comprise it, and the use of techniques within it, as well as their relationships. The chapter follows the widely accepted sequence for risk identification, assessment, execution, remediation and control; it starts with some basic definitions and, in its first topic, analyzes the sources for risks, considering internal and external risks and opportunities. It follows with a guide for identifying and managing risks in different areas of a project and suggests appropriate tools and techniques for each one. Completion of sequence sensitivity analysis, a subject developed in full …
Identification of biomarkers in wastewater-based epidemiology: Main approaches and analytical methods
2021
Wastewater-based epidemiology (WBE) has become popular to estimate the use of drugs of abuse and recently to establish the incidence of CoVID 19 in large cities. However, its possibilities have been expanded recently as a technique that allows to establish a fingerprint of the characteristics of a city, such as state of health/disease, healthy/unhealthy living habits, exposure to different types of contaminants, etc. with respect to other cities. This has been thanks to the identification of human biomarkers as well as to the fingerprinting and profiling of the characteristics of the wastewater catchment that determine these circumstances. The purpose of this review is to analyze the differ…
Challenges and directions for Blockchain technology applied to Demand Response and Vehicle-to-Grid scenarios
2021
Abstract Nowadays, Blockchain is considered a consolidated technology supporting many different applications that integrate well with Artificial Intelligence and the Internet of Things, and supports the creation of Decentralized Autonomous Organizations. Within this wider framework, the energy blockchain applications are now deserving more and more attention, since blockchain architectures, on one hand, provide transparency and solve the information asymmetry problem, on the other, provide disintermediation. In this way, the dream of an energy market closer to end-users becomes a reality, although, still, the regulatory framework is not clear, especially for what concerns the tokenization o…
A novel flash glucose monitoring system in patients with diabetes mellitus type 1 and 2: which are the pieces of evidence for payer decision-makers?
2018
A rigorous health technology assessment is necessary to evaluate a new technology. However, healthcare regulatory agencies have less restrictive rules about medical devices, despite some recent warnings about this relevant matter. The evaluation should have at least two key issues, which require attention. The first one is its effectiveness, and the second one is its economic sustainability. In this paper, we deal with a novel glucose-sensing technology as a case study to examine the matter in depth. An evidence-based point of view is used to highlight this important issue.
Managing Human Factors to Reduce Organisational Risk in Industry
2018
[EN] Human factors are intrinsically involved at virtually any level of most industrial/business activities, and may be responsible for several accidents and incidents, if not correctly identified and managed. Focusing on the significance of human behaviour in industry, this article proposes a multi-criteria decision-making (MCDM)-based approach to support organizational risk assessment in industrial environments. The decision-making trial and evaluation laboratory (DEMATEL) method is proposed as a mathematical framework to evaluate mutual relationships within a set of human factors involved in industrial processes, with the aim of highlighting priorities of intervention. A case study relat…
ANALYSIS OF IMPACTS ON ELECTRIC POWER SYSTEM OPERATION OF LOAD MANAGEMENT IN RESIDENTIAL AND TERTIARY BUILDINGS
2012
Load management includes all the techniques, logics, actions and programs through which the electric utilities and the customers are able to manage loads absorption in a more prudent and efficient way; it determines economic benefits for the users, but also allows a network management and operation simpler and cheaper, determining technical and economic benefits. The present paper constitutes a detailed study of interventions and techniques to control demand in the residential and tertiary sectors and the effects that these actions have on the entire electrical system and its management. It discusses the implications of such control actions in terms of reduction of network losses and relate…