Search results for "Rite"
showing 10 items of 2726 documents
Nuclear Translocation of Nuclear Transcription Factor-κB by α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors Leads to Transcription of …
2003
We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor κB (NFκB) in rat embryonic cultures of dopaminergic neurons. Treatment of mesencephalic cultures with α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) resulted in a number of changes that occurred selectively in dopaminergic neurons, including persistent elevation in intracellular Ca2+ monitored with Fura-2, and a significant increase in intramitochondrial oxidation of dihydrorhodamine 123, probably associated with transient increase of mitochondrial permeability, cytochrome c release, nuclear translocation of NFκB, and transcriptional activation of the oncogenep53.…
Poriferan survivin exhibits a conserved regulatory role in the interconnected pathways of cell cycle and apoptosis
2010
Survivin orchestrates intracellular pathways during cell division and apoptosis. Its central function as mitotic regulator and inhibitor of cell death has major implications for tumor cell proliferation. Analyses in early-branching Metazoa so far propose an exclusive role of survivin as a chromosomal passenger protein, whereas only later during evolution a complementary antiapoptotic function might have arisen, concurrent with increased organismal complexity. To lift the veil on the ancestral function(s) of this key regulator, a survivin-like protein (SURVL) of one of the earliest-branching metazoan taxa was identified and functionally characterized. SURVL of the sponge Suberites domuncula …
A proposal for sorting a projects portfolio through the ELECTRE TRI method focused on the European strategy
2019
In recent years, the partnerships between private companies and public organizations are becoming key elements for improving local development, territorial competitiveness, and delivering innovation. These collaborations are widely promoted by the European Framework Programme for Research and Innovation thanks to the provision of several instruments, such as Horizon 2020. In this context, competitiveness's improvement of the territory employing research and innovation actions is supported by the technological districts. In Sicily, the AgroBioPesca district has attempted a strategic action named "Call for ideas" in order to design its own roadmap for research and innovation in the agri-food …
Criteri di discretizzazione e di proiezione nel pensiero post-rinascimentale
2008
I metodi di rappresentazione descrivono le strutture di pensiero. E' ipotizzabile che nuovi sistemi di rappresentazione, quali gli schermi curvi, possano influenzare un nuovo modo di pensare e disegnare lo spazio, superando lo schema rinascimentale, che sottende, ancora oggi gli attuali sistemi di proiezione.
I lavacri inferi di Cornelio Gallo (Nota a Properzio, II 34, 91-92)
2011
Il ritratto di Cornelio Gallo che Properzio abbozza nella chiusa di II, 34 descrive un miles amoris intento a lavarsi le ferita infertegli da Licoride, l'amata, nell'Oltretomba rinnovando in senso elegiaco lo stereotipo dei lavacri funebri degli eroi caro all'epos greco e latino.
Utilizzo di modelli bimodali per la descrizione della curva di ritenzione idrica del suolo
2013
L’approfondimento dell’influenza della struttura sulle caratteristiche di ritenzione idrica del suolo può contribuire alla risoluzione dei problemi legati all’eterogeneità del mezzo poroso ed anche alla quantificazione della qualità fisica del suolo. In particolare, nei suoli naturali strutturati, la presenza di un dominio dei pori strutturali (porosità inter-aggregati) e di un dominio dei pori matriciali (porosità intra-aggregati) può essere descritta mediante un’espressione della curva di ritenzione idrica di tipo bi-modale. L’indagine ha riguardato 40 suoli siciliani, per i quali è stato applicato alle misure sperimentali di ritenzione idrica il modello bimodale proposto da Dexter et al.…
Ryt oczyszczenia, celebrowanie Paschy i święta Namiotów w ujęciu proroka Ezechiela (Ez 45,18-25)
2019
Ezechiel był prorokiem głoszącym sąd Boży nad Izraelem oraz nad narodami (Ez 1–32); zapowiadał również odnowę ludu Jahwe i jego ziemi (Ez 33–48). W nowym środowisku Izraela będzie odprawiony ryt oczyszczenia (Ez 45,18-20). Celebrowane będą także święta pielgrzymkowe: Pascha oraz Namiotów (Ez 45,21-25). Ezechiel nawiązuje więc do tradycji z okresu pierwszej świątyni, lecz jego ujęcie tych wydarzeń zostało w pełni dostosowane do nowych warunków – do okresu odnowy narodu i ziemi po powrocie ludu do ziemi przodków. Prorok Ezechiel znając tradycję obchodzenia świąt (~yGIx;), wspomina o nich wyłącznie w kontekście zapowiedzi nowego prawa świątynnego (Ez 45,17.21.23.25; 46,11). Będą to święta wyzn…
Analysis of serine proteases from marine sponges by 2-D zymography.
2007
Proteolytic activities isolated from the marine demosponges Geodia cydonium and Suberites domuncula were analyzed by 2-D zymography, a technique that combines IEF and zymography. After purification, a 200 kDa proteolytically active protein band was obtained from G. cydonium when analyzed in gelatin copolymerized 1-D zymograms. The enzymatic activity was quantified using alpha-N-benzoyl-D-arginine p-nitroanilide (BAPNA) as a substrate and corresponded to a serine protease. The protease activity was resistant to urea and SDS. DTT and 2-mercaptoethanol (2-ME) did not significantly change the protease activity, but induced a shift in molecular mass of the proteolytic band to lower M(r) values a…
Nucleation and Growth of CaCO3 Mediated by the Egg-White Protein Ovalbumin: A Time-Resolved in situ Study Using Small-Angle Neutron Scattering
2008
Mineralization of calcium carbonate in aqueous solutions starting from its initiation was studied by time-resolved small-angle neutron scattering (SANS). SANS revealed that homogeneous crystallization of CaCO 3 involves an initial formation of thin plate-shaped nuclei which subsequently reassemble to 3-dimensional particles, first of fractal and finally of compact structure. The presence of the egg-white protein ovalbumin leads to a different progression of mineralization through several stages; the first step represents amorphous CaCO 3, whereas the other phases are crystalline. The formation and dissolution of the amorphous phase is accompanied by Ca (2+)-mediated unfolding and cross-link…
Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inte…
2014
International audience; Sponges and bacteria have lived together in complex consortia for 700 million years. As filter feeders, sponges prey on bacteria. Nevertheless, some bacteria are associated with sponges in symbiotic relationships. To enable this association, sponges and bacteria are likely to have developed molecular communication systems. These may include molecules such as N-acyl-L-homoserine lactones, produced by Gram-negative bacteria also within sponges. In this study, we examined the role of N-3-oxododecanoyl-L-homoserine lactone (3-oxo-C12-HSL) on the expression of immune and apoptotic genes of the host sponge Suberites domuncula. This molecule seemed to inhibit the sponge inn…