Search results for "Rites"

showing 10 items of 427 documents

Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth

2010

Nerve Growth Factor (NGF)-induced neuronal differentiation requires the activation of members of the Rho family of small GTPases. However, the molecular mechanisms through which NGF regulates cytoskeletal changes and neurite outgrowth are not totally understood. In this work, we identify the Rac1-specific guanine exchange factor (GEF) Tiam1 as a novel mediator of NGF/TrkA-dependent neurite elongation. In particular, we report that knockdown of Tiam1 causes a significant reduction in Rac1 activity and neurite outgrowth induced by NGF. Physical interaction between Tiam1 and active Ras (Ras- GTP), but not tyrosine phosphorylation of Tiam1, plays a central role in Rac1 activation by NGF. In add…

rac1 GTP-Binding ProteinTiam1; Nerve growth factor (NGF)GTPaseTropomyosin receptor kinase ABiochemistryPC12 CellsCell Biology/Cell Signalingchemistry.chemical_compoundChlorocebus aethiopsNerve Growth FactorTiam1Guanine Nucleotide Exchange FactorsT-Lymphoma Invasion and Metastasis-inducing Protein 1NGFNeuronsMultidisciplinaryUNESCO::CIENCIAS DE LA VIDA::Biología molecularQOtras Medicina BásicaRCell Differentiation//purl.org/becyt/ford/3.1 [https]Cell biologyNeoplasm ProteinsMedicina BásicaNeuronal differentiationNerve growth factor (NGF)COS CellsMedicine//purl.org/becyt/ford/3 [https]Guanine nucleotide exchange factorSignal transductionResearch ArticleSignal TransductionCIENCIAS MÉDICAS Y DE LA SALUDNeuriteScienceCell Biology/Neuronal Signaling MechanismsRAC1Biology:CIENCIAS DE LA VIDA::Biología molecular [UNESCO]Neuroscience/Neuronal Signaling MechanismsNeuritesAnimalsHumansReceptor trkATyrosine phosphorylationMolecular biologyRatsNerve growth factorchemistrynervous systemras ProteinsRac1 GTPasePLoS ONE
researchProduct

Dekongestantu aprite Rīgas aptiekās

2017

Mūsdienas rinīts un alerģijas skar lielako daļu pasaules iedzīvotaju. Pie rinīta formu ārstēšanas un terapijas, tiek plaši pielietoti dekongestantu preparāti, kas samazina deguna gļotādas tūsku, izraisot asinsvadu sašaurināšanos. Šī darba mērķis bija analizēt dekongestantu preparātu apgrozījumu trīs Rīgas aptiekās laikā periodā 01.02.2016 līdz 30.01.2017, un noteikt dekongestantu preparātu apgrozījuma raditājus. Ar anketēšanas palīdzību tika noskaidrotas pacientu zināšanas par dekongestantu preparātiem un to kādi ir galvenie izvēles kritēriji, izvēloties dekongestanta preparātu. Tika konstatēts, ka 50% no aptaujātajiem respondentie, kuri lieto dekongestanta preparātus, nav informēti par to …

rinītsdekongestantu preparātialerģijaFarmācijadeguna aerosoliaprites analīze
researchProduct

Nitrate and nitrite in the diet: How to assess their benefit and risk for human health

2015

Nitrate is a natural constituent of the human diet and an approved food additive. It can be partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases blood pressure. This effect is associated with a reduced risk regarding cardiovascular disease, myocardial infarction, and stroke. Moreover, dietary nitrate has been associated with beneficial effects in patients with gastric ulcer, renal failure, or metabolic syndrome. Recent studies indicate that such beneficial health effects due to dietary nitrate may be achievable at intake levels resulting from the daily consumption of nitrate-rich vegetables. N-nitroso compounds are endogenously formed in humans. However…

risk analysisNitriteischemia-reperfusion injuryPhysiologyBenefitNitric OxideToxicologyNitratereduces blood-pressureNitric oxidechemistry.chemical_compoundNitrateRisk FactorsNeoplasmsVegetablesmedicineAnimalsHumansfluke opisthorchis-viverriniNitritenih-aarp dietNitritesToxicologiecolorectal-cancer riskCarcinogenRandomized Controlled Trials as TopicVLAGNitratesChemistryN-nitroso compoundsmedicine.diseasenitrosatable drug exposureDietMeat ProductsDisease Models Animaln-nitroso compoundsBlood pressureBiochemistryNitrosationMetabolic syndromecoronary-heart-diseaseRisk assessmentBiomarkersNitroso Compoundsinorganic nitrateneural-tube defectsFood ScienceBiotechnology
researchProduct

On pragmemes again: dealing with death

2010

rites of death
researchProduct

Are Brands Postmodern Relics? Taking a Closer Look at New Sacred Objects

2011

Summary : Ever since the Church lost its monopoly on the sacred, no longer able to solely determine its form or contents, the social sphere has gradually taken over this value, applying it to new human and social objects. As a result, the modes of expression of the sacred have multiplied, along with the subjective and intimate experiences of modern individualism. Among the vast number of potential manifestations of this value, to which almost everything now seems to aspire, this paper will concentrate on commercial brands as vectors of meaning, with the hypothesis that some of them seek to position themselves, in postmodern society, as new figures of the sacred. This area of study is close …

rites[SHS.INFO]Humanities and Social Sciences/Library and information sciencesCommunication. Mass mediaP87-96enunciation[SHS.INFO] Humanities and Social Sciences/Library and information sciencesmarquesemioticssacrébrandsémiotique[ SHS.INFO ] Humanities and Social Sciences/Library and information sciencesritualsénonciationsacred
researchProduct

First Evidence of Contourite Drifts in the North-Western Sicilian Active Continental Margin (Southern Tyrrhenian Sea)

2021

We present the results of an integrated geomorphological and seismo-stratigraphic study based on high resolution marine data acquired in the north-western Sicilian continental margin. We document for the first time five contourite drifts (marked as EM1a, EM2b, EM2, EM3a, and EM3b), located in the continental slope at depths between ca. 400 and 1500 m. EM1a,b have been interpreted as elongated mounded drifts. EM1a,b are ca. 3 km long, 1.3 km wide, and have a maximum thickness of 36 m in their center that thins northwards, while EM1b is smaller with a thickness up to 24 m. They are internally characterized by mounded seismic packages dominated by continuous and parallel reflectors. EM2 is loc…

seismic reflection dataSettore GEO/02 - Geologia Stratigrafica E SedimentologicaSettore GEO/03 - Geologia StrutturaleSettore GEO/04 - Geografia Fisica E GeomorfologiaNaval architecture. Shipbuilding. Marine engineeringVM1-989Ocean EngineeringGC1-1581OceanographyPaleontologyMediterranean seaContinental marginAggradationMediterranean Seacontinental slopemoatHoloceneWater Science and TechnologyCivil and Structural Engineeringgeographygeography.geographical_feature_categoryContinental shelfcontouritesContouriteSeafloor spreadinglanguage.human_languagelanguagebottom currentsSiciliancontourites; bottom currents; continental slope; moat; seismic reflection data; Mediterranean SeaGeology
researchProduct

Shallow structures at the outer Calabrian accretionary wedge (NW Ionian Sea): new insights from recently migrated reflection data

2010

seismic reflection Messinian evaporites
researchProduct

Rikoksista tuomitut naiset : yhteisöstä erottaminen ja takaisinliittymisen mahdollisuudet

2019

Tutkimus käsittelee yhteisöstä erottamisen ja siihen takaisinliittymisen mahdollisuuksia rikostaustaisten naisten elämässä. Tutkimuksen kohteena ovat rikostaustaisten naisten kertomukset elämänkulustaan. Tutkimuksessa analysoidaan naisten kertomuksia siirtymäriittiteorian eli yhteisöstä erottamisen, liminaalin ja takaisinliittämisen näkökulmasta. Aineisto on kerätty haastattelemalla 18 naista, jotka haastatteluhetkellä olivat joko suorittamassa vankeusrangaistustaan, ehdonalaisen vapauden valvonnassa tai rangaistuksensa suorittaneet. Aineiston analyysissa on käytetty narratiivista lähestymistapaa sekä Greimasin aktanttimallia. Aineiston analyysissa esiin nousevia keskeisiä teemoja ovat päih…

separationnaisetliminalitysiirtymäriititfemale offendersvankeuswomen in prisonväkivaltasubstance usecritical criminologyrites of passagefeminist criminologyfeministinen kriminologiacriminal backgroundviolencerikostaustanaisvangitwomenkriittinen kriminologiapäihteiden käyttö
researchProduct

"Antavat anteeksi ovenvieret" : Matjoi Plattosen kuolinriittikuvaukset siirtymäriittiteorian valossa

2019

Tässä tutkimuksessa tarkastellaan suistamolaiselta itkijältä Matjoi Plattoselta vuosina 1908−1920 tallennettuja kuolinrituaalien kuvauksia ja niihin liittyviä itkuvirsiä siirtymäriittiteorian avulla. Tutkimuksen aineiston Plattosen kanssa ovat tuottaneet Matti Kaisla, U. T. Sirelius ja A. O. Väisänen. Tutkimuksessa kiinnitetään huomiota erityisesti rituaalisen itkemisen merkitykseen kuolinrituaalien osana. Yksilön tai ryhmän sosiaalisen kategorisen muutoksen yleismaailmallisesti kolmeen vaiheeseen jakavan siirtymäriittiteorian kehitti etnologi Arnold van Gennep (1873−1957). Hän väitti, että rituaaliset seremoniat, jotka liittyvät ihmiselämän tärkeimpiin muutoksiin, eroavat toisistaan eri ku…

siirtymäriititGR1-950semiotic analysisrites of passagedeath ritualssemioottinen analyysiHistory (General)kuolemaitkuvirretGN1-890rituaalitkarjaladeathAnthropologyDD1-2009siirtymäriittiteoriakuolemanrituaalitHistory (General) and history of EuropekareliaitkutKarjalaFolklorelaments
researchProduct

Sinkholes: dissoluzione delle evaporiti in Sicilia centromeridionale

2013

sinkholes mine evaporites salt hazardSettore GEO/05 - Geologia Applicata
researchProduct