Search results for "Roca"
showing 10 items of 1893 documents
CCDC 141172: Experimental Crystal Structure Determination
2001
Related Article: Young Lag Cho, D.M.Rudkevich, A.Shivanyuk, K.Rissanen, J.Rebek Junior|2000|Chem.-Eur.J.|6|3788|doi:10.1002/1521-3765(20001016)6:20<3788::AID-CHEM3788>3.0.CO;2-Y
Realización de un electrocardiograma
2010
Procedimiento a realizar para obtener un registro electrocardiográfico. Preparación del paciente y del electrocardiógrafo.
A subset of flavaglines inhibits KRAS nanoclustering and activation.
2020
The RAS oncogenes are frequently mutated in human cancers and among the three isoforms (KRAS, HRAS and NRAS), KRAS is the most frequently mutated oncogene. Here, we demonstrate that a subset of flavaglines, a class of natural anti-tumour drugs and chemical ligands of prohibitins, inhibit RAS GTP loading and oncogene activation in cells at nanomolar concentrations. Treatment with rocaglamide, the first discovered flavagline, inhibited the nanoclustering of KRAS, but not HRAS and NRAS, at specific phospholipid-enriched plasma membrane domains. We further demonstrate that plasma membrane-associated prohibitins directly interact with KRAS, phosphatidylserine and phosphatidic acid, and these int…
Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales
2014
“Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales” es la primera parte de un trabajo de documentación para un capítulo de “La democracia en la Comunidad Valenciana. Partidos, elites políticas, elecciones y programas políticos”. “Mujer, poder político y democracia paritaria”. Se recoge el papel de la mujer en la vida política de la Comunidad Valenciana en la democracia actual, desde 1977. Es documentación sin elaborar, pero que aporta datos de la presencia de la mujer en las instituciones, partidos y sindicatos. Cuando este completa será una parte de la investigación referida, y de la que ya hay dos publicacion…
Berrocal Lanzarot, A. L. : Estudio jurídico-crítico sobre la ley orgánica 3/2018, de 5 de diciembre, de protección de datos personales y garantía de …
2021
Síntesis y caracterización de materiales basados en los sistemas Pr-ZrO2 y Pr-ZrSiO4. Propiedades y aplicaciones.
2014
En el presente trabajo se estudian las disoluciones sólidas Pr-ZrSiO4 y Pr-ZrO2. La disolución sólida Pr-ZrSiO4 despierta un gran interés a nivel industrial por su estabilidad química y su aplicación como pigmento cerámico. Este pigmento presenta una coloración amarilla debido al catión praseodimio y ha sido ampliamente estudiado para mejorar su producción industrial. Sin embargo, en este trabajo se realiza un estudio de la disolución sólida Pr-ZrSiO4 para profundizar en sus características estructurales y microestructurales. Así se han tratado diferentes aspectos tales como el intervalo composicional de la disolución sólida, la ocupación del catión praseodimio en la estructura de circón y …
Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycl…
2009
Background The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. Design and Methods Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enrolled in two consecutive trials (PETHEMA LPA96 and LPA99) received induction therapy-with all-trans retinoic acid and idarubicin. Consolidation therapy comprised three courses of anthracycline monochemotherapy (LPA96), with all-trans retinoic acid and reinforced doses of idarubicin in patients with an intermediate or high risk of relapse (LPA99). Central nervous system prophylaxis was not given. Re…
Perspectives for the Treatment of Brucellosis in the 21st Century: The Ioannina Recommendations
2007
Policy Forum. Competing interests: ER has received research grants from Daiichi, Bayer, and Theravance and has served as a consultant to Pfizer, Theravance, Bayer, Wyeth, Rosetta, and BiondVax. Summary Points Brucellosis remains the commonest anthropozoonosis worldwide, and its treatment remains complex, requiring protracted administration of more than one antibiotic. In November 2006, a consensus meeting aimed at reaching a common specialist statement on the treatment of brucellosis was held in Ioannina, Greece under the auspices of the International Society of Chemotherapy and the Institute of Continuing Medical Education of Ioannina. The author panel suggests that the optimal treatment o…
El paisatge vegetal de la Marina, a partir dels carbons prehistòrics
1997
Badal Garcia, Ernestina - Ernestina.Badal@uv.es
Vaccinium macrocarpon (Cranberry)-Based Dietary Supplements: Variation in Mass Uniformity, Proanthocyanidin Dosage and Anthocyanin Profile Demonstrat…
2020
Vaccinium macrocarpon (syn. American Cranberry) is employed in dietary supplements (DS) with the aim to improve urinary tract well-being. This property is linked to the antiadhesion-activity of proanthocyanidins (PACs) against uropathogenic-bacteria. However, the current European legislation has been criticized for being weak and ineffective. Indeed, recent scientific works report mislabeled, contaminated, and adulterated supplements containing dangerous or unknown compounds, or sold at toxic doses. In this work, we analysed 24 DS that claim to contain cranberry, and to have a specific dosage of PACs. Our tests included the control of the good manufacturing practice according to the Europea…