Search results for "Roche"

showing 10 items of 2666 documents

Préface

2009

L'orientation scolaire et professionnelle, l'orientation des adultes et la formation au long de la vie peuvent être approchées selon des points de vue disciplinaires différents. Dans le cadre de cette préface nous limiterons notre approche aux dimensions sociopolitiques, locales et internationales, pédagogiques, économiques et psychologiques de l'orientation. Ces approches permettent de proposer une compréhension de la démarche scientifique anthropologique de Francis Danvers.

Approche économiqueApproche socio-politiqueApproche territorialeFormation tout au long de la vieApproche psychologique[SHS.EDU] Humanities and Social Sciences/EducationApproche pédagogiqueFormation des adultesOrientation scolaire et professionnelle
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Pour une approche économique de la liaison éducation-loisir

1976

International audience

Approche économiqueEffet[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationLoisirsÉducation[SHS.ECO]Humanities and Social Sciences/Economics and Finance[SHS.ECO] Humanities and Social Sciences/Economics and FinanceConsommationComputingMilieux_MISCELLANEOUS
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The Financing of Education : An Economic Issue ?

2000

Building on previous contributions on the same topic, this article gives a brief overview of the financial situation of Education in the different regions of the world then focuses on the shortcomings of the traditional treatment of financing issues by economist among them the quasi absence of equity consideration. It ends by discussing the main issues as they can be seen today : extent of the "right to education", demand side approach to education financing, choice between various types of subsides to students.

Approche économiqueWelfare economics[SHS.EDU]Humanities and Social Sciences/Education05 social sciences[SHS.EDU] Humanities and Social Sciences/Education050301 educationSubsidyEducationFinancement de l'éducationEconomic issue0502 economics and businessEthnologySociologyPrivate education050207 economics0503 educationEducation economics
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Quel accès aux soins pour les patients vulnérables? Une approche économique

2013

National audience

Approche économique[ SHS.ECO ] Humanities and Social Sciences/Economies and financesPatients vulnérables[SHS.ECO]Humanities and Social Sciences/Economics and Finance[SHS.ECO] Humanities and Social Sciences/Economics and FinanceComputingMilieux_MISCELLANEOUSAccès aux soins
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Efficacité éducative. L'approche économique

2015

National audience; L'efficacité est au cour même de la démarche économique. Celle-ci peut se définir comme la quête d'une situation optimale, puisque sa recherche revient à minimiser 1' écart entre une situation réelle et un optimum théorique correspondant à la meilleure situation possible d'allocation des moyens pour tous les intervenants dans cette sphère économique. Nous pouvons introduire l'efficacité économique comme un double objectif: celui d'obtenir la fourniture du meilleur service éducatif à un coût financier donné et de fournir ce service au plus grand nombre de façon équitable. Autrement dit l'action économique vers l'éducation doit satisfaire le double objectif simultané d'obli…

Approche économique[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Education[ SHS.EDU ] Humanities and Social Sciences/EducationEfficacité de l'éducation
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An Economic Approach of Higher Education in Brazil

1995

International audience; Higher education in Latin America is considered by many to be in a state of crisis. In Brazil this is certainly the case. In the press and regularly in meetings and discussions in Brazil there is a growing debate about whether public education is excessively costly, inequitable, and inefficient, about the proper role of private institutions, and overall on how the system should change to meet the challenges of the 21st century. A major problem in this debate is a lack of real data and information on the issues under discussion. The purpose of this paper is to provide better information on these points of debate. Specitically, this paper seeks to answer the following …

Approche économiqueÉconomie de l'éducation[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationBourgogneFranceEnseignement
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Approches économiques des dynamiques urbaines

2014

Rapport d’activité – suivi des recherches,.Convention MSH – PUCA, juillet 2014

Approches économiques[ SHS.ECO ] Humanities and Social Sciences/Economies and financesDynamiques urbaines[SHS.ECO]Humanities and Social Sciences/Economics and Finance[SHS.ECO] Humanities and Social Sciences/Economics and Finance
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Insight into the Mechanism of Action of Marine Cytotoxic Thiazinoquinones

2017

The electrochemical response of four natural cytotoxic thiazinoquinones isolated from the Aplidium species was studied using conventional solution-phase and solid-state techniques, based on the voltammetry of immobilized particles methodology. The interaction with O-2 and electrochemically generated reactive oxygen species (ROS) was electrochemically monitored. At the same time, a molecular modeling study including density functional theory (DFT) calculations was performed in order to analyze the conformational and electronic properties of the natural thiazinoquinones, as well as those of their reduced intermediates. The obtained electrochemical and computational results were analyzed and c…

Aquatic OrganismsMolecular modelStereochemistryBioactive natural products; Cytotoxic activity; DFT calculations; Electrochemistry; Reactive radical species; Thiazinoquinones; Animals; Electrochemistry; Quinones; Reactive Oxygen Species; Aquatic Organisms; Urochordata; Drug Discovery3003 Pharmaceutical ScienceThiazinoquinoneDFT calculationPharmaceutical Science02 engineering and technologyDFT calculationsElectrochemistry01 natural sciencesArticleAplidiumbioactive natural products; thiazinoquinones; electrochemistry; DFT calculations; reactive radical species; cytotoxic activityComputational chemistryDrug DiscoverymedicineAnimalsCytotoxic T cellUrochordataBioactive natural productlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Voltammetrycytotoxic activitychemistry.chemical_classificationReactive oxygen speciesbiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceQuinonesReactive radical specie021001 nanoscience & nanotechnologybiology.organism_classification0104 chemical scienceslcsh:Biology (General)electrochemistryMechanism of actionchemistryreactive radical speciesbioactive natural productsthiazinoquinonesDensity functional theorymedicine.symptomReactive Oxygen Species0210 nano-technologyMarine Drugs
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Proton coupled electron transfer of ubiquinone Q2 incorporated in a self-assembled monolayer.

2011

We present a complete study of the reduction of ubiquinone Q(2) (UQ(2)) in simpler aqueous medium, over a pH range of 2.5 to 12.5. The short isoprenic chain ubiquinones (UQ(2)) were incorporated in a self-assembled monolayer. Under these conditions, the global 2e(-) electrochemical reaction can be described on the basis of a nine-member square scheme. The thermodynamic constants of the system were determined. The global 2e(-) process is controlled by the uptake of the second electron. The elementary electrochemical rate constants obtained by fitting of the experimental rate constant were k(s4) = 1.5 s(-1) for QH˙(+)(2)↔ QH(2), k(s5) = 1.5 s(-1) for QH˙↔ QH(-) and k(s6) = 1 s(-1) for Q˙(-)↔ …

Aqueous mediumChemistrySurface PropertiesUbiquinoneAnalytical chemistryGeneral Physics and AstronomyWaterSelf-assembled monolayerElectronHydrogen-Ion ConcentrationElectrochemistryElectron TransportReaction rate constantCoenzyme Q – cytochrome c reductaseMonolayerElectrochemistryThermodynamicsGoldPhysical and Theoretical ChemistryProton-coupled electron transferProtonsOxidation-ReductionPhysical chemistry chemical physics : PCCP
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Voltammetric behavior of berenil.

1993

Abstract Berenil is reduced on mercury drops electrode in buffered aqueous media. The reduction of —N=N— group is controlled by diffusion. Polarographie waves are of analytical usefulness. The hydrogen discharge is favored by the basic centers of the molecule in Co(ll)/ammonia-buffered media.

Aqueous mediumHydrogenAnalytical chemistryPharmaceutical Sciencechemistry.chemical_elementHydrogen-Ion ConcentrationTrypanocidal AgentsMercury (element)chemistryElectrodeElectrochemistryMoleculeVoltammetryDiminazeneElectrodesOxidation-ReductionPolarographyJournal of pharmaceutical sciences
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