Search results for "Rodent"
showing 10 items of 199 documents
Mio-Pliocene rodent assemblages from Alcoi Forn (Alcoy Basin, Eastern Spain). Biostratigraphical and palaeoclimatical inferences
2015
AbstractIn this work, we describe four new micromammal sites in the northern side of the Gormaget ravine, in the Alcoy Basin (Spain): AF-1’06, AF-1’07, AF-1A and AF-2. Based on the study of the faunal remains from these localities, we infer a latest Turolian-earliest Ruscinian age for AF-1’06 and AF-1A, and an earliest Ruscinian age for AF-1’07 and AF-2. The species assemblage of the locality AF-1’06, the only one which have yielded a sufficient number of remains to perform a palaecological analysis, shows warm and dry conditions near the Mio-Pliocene boundary in the Alcoy Basin. These data show a reduction of dry and warm indicators from older to younger localities in the Alcoy Basin, sugg…
Activation of Intestinal Epithelial Stat3 Orchestrates Tissue Defense during Gastrointestinal Infection
2015
Gastrointestinal infections with EHEC and EPEC are responsible for outbreaks of diarrheal diseases and represent a global health problem. Innate first-line-defense mechanisms such as production of mucus and antimicrobial peptides by intestinal epithelial cells are of utmost importance for host control of gastrointestinal infections. For the first time, we directly demonstrate a critical role for Stat3 activation in intestinal epithelial cells upon infection of mice with Citrobacter rodentium - a murine pathogen that mimics human infections with attaching and effacing Escherichia coli. C. rodentium induced transcription of IL-6 and IL-22 in gut samples of mice and was associated with activat…
Xenon treatment improves short-term and long-term outcomes in a rodent model of traumatic brain injury
2018
Vascular aging in rodent models: contrasting mechanisms driving the female and male vascular senescence
2021
Increasing scientific interest has been directed to sex as a biological and decisive factor on several diseases. Several different mechanisms orchestrate vascular function, as well as vascular dysfunction in cardiovascular and metabolic diseases in males and females. Certain vascular sex differences are present throughout life, while others are more evident before the menopause, suggesting two important and correlated drivers: genetic and hormonal factors. With the increasing life expectancy and aging population, studies on aging-related diseases and aging-related physiological changes have steeply grown and, with them, the use of aging animal models. Mouse and rat models of aging, the most…
The life cycle ofBrachylaima ruminae n. sp. (Trematoda: Brachylaimidae), a parasite of rodents
1986
The life cycle of Brachylaima ruminae n.sp. (Trematoda: Brachylaimidae), a duodenal parasite of rodents on the Mediterranean island of Formentera (Spain) is elucidated. The new species follows a terrestrial triheteroxenous life cycle. Eggs passed in the faeces of the definitive host must be ingested by a specific first intermediate host, the land snail Rumina decollata. Branched cercariogenous sporocysts develop in the digestive gland. Microcercous cercariae come out through the terminal birth pores of the branches. Cercariae shed by the snail are terrestrial, crawling on humid substratum. They contact the second intermediate host, another land snail, principally the species R. decollata an…
Reservoir computing model of prefrontal cortex creates novel combinations of previous navigation sequences from hippocampal place-cell replay with sp…
2019
As rats learn to search for multiple sources of food or water in a complex environment, they generate increasingly efficient trajectories between reward sites. Such spatial navigation capacity involves the replay of hippocampal place-cells during awake states, generating small sequences of spatially related place-cell activity that we call “snippets”. These snippets occur primarily during sharp-wave-ripples (SWRs). Here we focus on the role of such replay events, as the animal is learning a traveling salesperson task (TSP) across multiple trials. We hypothesize that snippet replay generates synthetic data that can substantially expand and restructure the experience available and make learni…
A new species of glirid rodent Vasseuromys from the Aragonian (Miocene) of the Ebro Basin (North−Eastern Spain)
2012
We describe a new species of Vasseuromys from the locality of Pico del Fraile 2 (PF2) in the Ebro Basin of northeastern Spain, which has yielded a fauna comprising several rodents and insectivores (Eumyarion cf. weinfurteri, Mega−cricetodon cf. primitivus, Democricetodon aff. hispanicus, Spermophilinus cf. besana, Microdyromys cf. legidensis, Galerix sp., and Lagomorpha indet.) indicative of Aragonian zones C or D. Vasseuromys cristinae sp. nov. differs from other Vasseuromys species in the constant presence of four extra ridges on the lower molars, one of them being connected to the posterolophid in the posterior valley, as well as three extra ridges on the upper molars, with none of them …
The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model
2021
Advancements in type 1 diabetes mellitus treatments have vastly improved in recent years. The move toward a bioartificial pancreas and other fully implantable systems could help restore patient's glycemic control. However, the long-term success of implantable medical devices is often hindered by the foreign body response. Fibrous encapsulation "walls off" the implant to the surrounding tissue, impairing its functionality. In this study we aim to examine how streptozotocin-induced diabetes affects fibrous capsule formation and composition surrounding implantable drug delivery devices following subcutaneous implantation in a rodent model. After 2 weeks of implantation, the fibrous capsule sur…
Odontometrical divergence in the Gerbe's vole Microtus (Terricola) pyrenaicus gerbei (GERBE, 1879) in comparison to the Pyrenean vole M. (Terricola) …
2010
This study confi rms the odontometrical divergence of the fi rst lower molar in the Gerbe’s vole Microtus (Terricola) pyrenaicus gerbei in comparison with the Pyrenean vole M. pyreneaicus pyrenaicus as well as the interest of genetic analyses to resolve its systematic position with regard to Microtus (Terricola) pyrenaicus.
A propos de l'observation de cas de campagnols des champs Microtus arvalis (Pallas, 1778) (Rodentia, Arvicolinae) caractérisés par une première molai…
2008
About some cases of common voles Microtus arvalis (Pallas, 1778) (Rodentia, Arvicolinae) characterised by a first lower molar with a pitymyan rhombus. This note describes and comments on some cases of common voles Microtus arvalis (Pallas, 1778) characterised by a first lower molar with a pitymyan rhombus.