Search results for "Romania"
showing 10 items of 326 documents
Cholelithiasis in Patients with Gaucher Disease type 1: Risk Factors and the Role of ABCG5/ABCG8 Gene Variants
2016
Background & Aim: Patients with Gaucher disease type 1 (GD1) show an altered lipid profile and a certain degree of insulin resistance, which might contribute to cholelithiasis (CL) and could possibly be associated with ABCG5/ABCG8 gene variants. We aimed to investigate the prevalence of CL in Caucasian adult patients with GD1 and the possible risk factors, including gene variants of the ABCG5/ABCG8 genes.
 Methods: 61 Caucasian patients with GD1 (38 female/23male), aged 18-62 years and 61 healthy subjects matched for age, gender and BMI, without CL, for comparison of lipid profiles. Data before start of enzyme replacement therapy (ERT) were recorded: clinical, haematological, sever…
Outcome of enzyme replacement therapy in patients with Gaucher disease type I. The Romanian experience
2007
This study reports the first evaluation of therapeutic response in Romanian patients with Gaucher disease type I, after therapy with Cerezyme recently became available in our country.24 patients (11-50 years) received Cerezyme 20-60 U/kg every two weeks for at least 18 months. Haemoglobin, platelet count, volume of the liver and spleen, plasma chitotriosidase and the severity score were assessed every 6 months; skeletal radiography and osteodensitometry were also monitored.Eleven patients were splenectomized before start of therapy. Eight patients had anaemia (mean haemoglobin 9.4 g/dl) and 14 patients, of whom 13 were without splenectomy, had thrombocytopenia (mean 65,692/mm3). Haemoglobin…
The impact of some behavioral aspects on periodontal disease in a group of Romanian students - an epidemiological survey.
2014
Abstract Aims To investigate the prevalence of periodontitis in a young population representative for the North-western part of Romania (Transylvania) and to identify possible risk indicators of periodontitis. Methods The study is a cross-sectional epidemiological survey. The subjects were students randomly sampled from three universities in Cluj-Napoca and high school students from the neighboring city of Bistrita. The sample size of the population was calculated. Overall, 623 subjects aged 16–35 years were evaluated, of which 488 were university students and 135 high school students. A structured questionnaire was administrated to collect information on socio-behavioral status and oral hy…
21-Hydroxylase and 11beta-hydroxylase mutations in Romanian patients with classic congenital adrenal hyperplasia.
2005
Congenital adrenal hyperplasia (CAH) comprises autosomal recessive disorders mainly due to defects in the 21-hydroxylase (CYP21) gene.The study aimed to perform molecular characterization in 43 Romanian patients with classical CAH forms diagnosed at the Center for Genetic Diseases of the Pediatric Clinic/University Cluj (38 with 21-hydroxylase deficiency, five with 11beta-hydroxylase deficiency), to determine the frequency of mutations in the CYP21A2 gene and attempt a genotype-phenotype correlation in patients with 21-hydroxylase deficiency.Molecular analysis was performed by direct sequencing of PCR amplified products of the CYP21A2 and CYP11B1 genes.The most frequent mutation in Romanian…
Baseline characteristics and outcome in Romanian patients with Gaucher disease type 1.
2009
Abstract Background/aim To present clinical and genetic characteristics of all Romanian patients with Gaucher disease type 1, in whom specific diagnosis has been confirmed by enzymatic and molecular methods and to analyze their outcome with and without enzymatic replacement therapy (ERT). Patients, methods There are fifty patients (F/M — 1.63/1) with Gaucher disease type 1. Clinical status, haemoglobin, thrombocytes, hepatic/splenic volume, bone mineral density and severity score were assessed at baseline and every six months thereafter. Thirty-nine patients (78%) received imiglucerase (44.4 ± 13.6 U/kg/2 weeks) for 3.1 +/− 1.4 years. Results Based on general prevalence data, our group repr…
Use of Yoghurt Enhanced with Volatile Plant Oils Encapsulated in Sodium Alginate to Increase the Human Body’s Immunity in the Present Fight Against S…
2020
(1) Background: The COVID&ndash
La inserción laboral de los inmigrantes rumanos y búlgaros en España
2008
Este artículo analiza la incorporación al mercado de trabajo español de los inmigrantes de nacionalidad búlgara y rumana, dos de los colectivos extranjeros que más han crecido en los últimos años. Tras elaborar un breve estado de la cuestión sobre el tema, se analiza su evolución numérica reciente y su distribución geogràfica a nivel de Comunidades Autónomas, sus características sociodemográficas y laborales a partir de la EPA y, finalmente, su inserción laboral por sector de actividad desde la perspectiva de la complementariedad con la población española ocupada en esos mismos sectores. Las conclusiones se centran en subrayar tanto las semejanzas como las diferencias existentes entre ambos…
Shifting urban namescapes: street name politics and toponymic change in a Romanian(ised) city
2019
Abstract Street names express the spatial materialisation of nominative discourses articulated and deployed by the powerful in their politicisation of the urban landscape with self-legitimising ideological values, political symbols and historical narratives. Using an approach grounded upon the theoretical principles of critical toponymies, this paper sets out a longitudinal perspective on the politics of street nomenclature in Hermannstadt/Sibiu (Romania). For this purpose, a dataset comprising the complete historical record of street names in Sibiu between 1829 and 2018 was constructed. The analysis focuses on capturing the ethnopolitics played out at the level of the city's street names t…
Sexual Exploitation in the Destination Country
2020
When the vulnerability of Nigerian and Romanian women in human trafficking is concerned, it is not only important to understand the causes that led the victim into a situation of trafficking, but also to understand the factors that maintain the individual in a situation of victimisation. However, this does not mean that these factors are separated according to the different phases of trafficking. On the contrary, it demonstrates that the accumulation of different factors can generate a higher or lower level of vulnerability, as well as the balance of factors affecting the women during the different phases. Therefore, in this chapter I will put forward a general analysis of the different fac…
Can google trends and wikipedia help traditional surveillance? A pilot study on measles
2019
Introduction: Cases of measles in some European countries are increasing. The aim of this study is to find the correlation between Google Trends and Wikipedia searches and the real number of cases notified. Materials and Methods: The data on Internet searches have been obtained from Google Trends and Wikipedia. The reported cases of measles were selected from January 2013 until December 2018 for Google Trends and July 2015 until December 2018 from for Wikipedia. We have selected data from four European Countries: Italy, France, Germany and Romania. The data extracted from Wikipedia and Google Trends have been moved over time (Lag), one month in the future and one month in the past. Cross-co…