Search results for "Rome"
showing 10 items of 12914 documents
Prediction of vascular events in subjects with subclinical atherosclerosis and the metabolic syndrome: the role of markers of inflammation.
2010
Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium.
2017
Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia. The present study was conducted in order to evaluate neuronal effects of SUG alone and in combination with both ROC and VEC. Using MTT, CASP-3 activity and Western-blot we determined the toxicity of SUG, ROC or VEC in neurons in primary culture. SUG induces apoptosis/necrosis in neurons in primary culture and increases cytochrome C (CytC), apoptosis-inducing factor (AIF), Smac/Diablo and Caspase 3 (CASP-3) protein expression. Our results also demonstrated that both ROC and VEC prevent these…
The role of lipid metabolism in the acquisition of desiccation tolerance inCraterostigma plantagineum: a comparative approach
2013
Summary Dehydration leads to different physiological and biochemical responses in plants. We analysed the lipid composition and the expression of genes involved in lipid biosynthesis in the desiccation-tolerant plant Craterostigma plantagineum. A comparative approach was carried out with Lindernia brevidens (desiccation tolerant) and two desiccation-sensitive species, Lindernia subracemosa and Arabidopsis thaliana. In C. plantagineum the total lipid content remained constant while the lipid composition underwent major changes during desiccation. The most prominent change was the removal of monogalactosyldiacylglycerol (MGDG) from the thylakoids. Analysis of molecular species composition rev…
Dynaamiset keuhkotoiminnat kilpauimareilla maalla ja vedessä sekä maksimaalisen uintikuormituksen yhteydessä
2002
Marja Päivinen Dynaamiset keuhkotoiminnat kilpauimareilla maalla ja vedessä maksimaalisen uintikuormituksen yhteydessä. Liikuntajj;siologian pro gradu-tutkielma. Liikuntabiologian laitos. Jyväskylän Yliopisto. Hengitys on tärkeä osa kestävyysurheilusuoritusta. Uinnin hengitys eroaa maalla tehtävien lajien hengityksestä monin tavoin. Sisäänhengitys ja uloshengitys tapahtuvat käsivetorytmin mukaan, uloshengitys tapahtuu veden aiheuttamaa vastusta vastaan ja kehonasento on vaakatasossa. Lisäksi ympäröivä vesi puristaa elimistöä ja johtaa lämpöä tehokkaasti vaikuttaen uinnin aikaiseen hengitykseen. Tässä tutkimuksessa selvitettiin pitkän uintiharjoitustaustan omaavien ja kokeneiden kilpauimarei…
La reputazione dell'altro. Vergogna e capro espiatorio.
2020
La vergona, come emozione complessa, è riconosciuta nella sua funzione positiva di protezione e tutela dell'identità personale, come l'affetto chiave della psicologia del Sè. Il rapporto tra vergogna e reputazione, viene chiarito nella proiezione della propria immagine sociale nella comunità moderna. Numerose ricerche confermano che provare sentimenti di frustrazione e di umiliazione, in fase comunicativa, conduca ad agire in modo aggressivo, con più facilità. Si tratta di trovare un buon compromesso tra spazio pubblico e privato, tra il Sè dell'individuo e il mondo con il quale viene a patti, lasciando spazio all'emergere spontaneo della creatività e delle proprie emozioni.
El síndrome de burnout en profesionales que trabajan en violencia de género
2006
se señalan los riesgos de padecer burnout en profesionales que trabajan con violencia de género: contaminación temática, traumatización vicaria y traumatización de los equipos así como las estrategias de cuidado personales y del equipo
Virtuālas ģeogrāfiskas sētas uzstādīšana suņa atrašanās vietas ierobežošanai izmantojot Globālās pozicionēšanas sistēmu
2018
Sistēmas mērķis ir spēja reāllaikā ierobežot suņa pārvietošanos noteiktā virtuālā ģeogrāfiskā sētā pēc iespējas saudzīgākā veidā. Tas tiks panākts izmantojot arduino, akselerometru, GPS moduli, GSM/GPRS moduli, skaņas signālu, ultraskaņas signālu un tīmekļa vietni, kurā būtu iespējams uzstādīt šīs koordinātes un redzēt suņa atrašanās vietu. Šajā kvalifikācijas darbā tika izstrādāta daļa no šīs sistēmas, kas ir tās kodols – suņa ierobežošana ar skaņas signālu balstoties uz GPS un akselerometra datiem.
IgA-Dominant Infection-Associated Glomerulonephritis Following SARS-CoV-2 Infection
2021
The renal involvement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported. The etiology of kidney injury appears to be tubular, mainly due to the expression of angiotensin-converting enzyme 2, the key joint receptor for SARS-CoV-2; however, cases with glomerular implication have also been documented. The multifactorial origin of this renal involvement could include virus-mediated injury, cytokine storm, angiotensin II pathway activation, complement dysregulation, hyper-coagulation, and microangiopathy. We present the renal histological findings from a patient who developed acute kidney injury and de novo nephrotic syndrome, highly suggestive of acute IgA-domina…
Immune responses during COVID-19 infection
2020
International audience; Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics. The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health care and economic systems across the world. This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. While protective humoral and cellular immune responses are usually m…
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations.
2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents the most severe global health crisis in modern human history. One of the major SARS-CoV-2 virulence factors is nonstructural protein 1 (Nsp1), which, outcompeting with the binding of host mRNA to the human ribosome, triggers a translation shutdown of the host immune system. Here, microsecond-long all-atom simulations of the C-terminal portion of the SARS-CoV-2/SARS-CoV Nsp1 in complex with the 40S ribosome disclose that SARS-CoV-2 Nsp1 has evolved from its SARS-CoV ortholog to more effectively hijack the ribosome by undergoing a critical switch of Q/E158 and E/Q159 residues that perfects Nsp1's interactions…