Search results for "Romu"

Impact of COVID-19 in AChR Myasthenia Gravis and the Safety of Vaccines: Data from an Italian Cohort.

2022

Background and aims. Patients with Myasthenia gravis (MG) are considered vulnerable as they may present with respiratory muscle weakness and because they are on immunosuppressive treatment; thereby, COVID-19 may have a detrimental effect on these patients. Vaccines against COVID-19 are currently available and it has been shown as they can prevent severe COVID-19 in vulnerable patients. Notwithstanding their efficacy, vaccine hesitancy has not been completely dispelled in the general population. Unfortunately, there is limited data about the safety of these vaccines in MG patients. The aims of this study are to evaluate the impact of COVID-19 in a MG cohort, the adherence to COVID-19 vaccina…

Neuromuscolar disorders and non compaction reply

2009

Mental fatigue induced by prolonged self-regulation does not exacerbate central fatigue during subsequent whole-body endurance exercise

2015

International audience; It has been shown that the mental fatigue induced by prolonged self-regulation increases perception of effort and reduces performance during subsequent endurance exercise. However, the physiological mechanisms underlying these negative effects of mental fatigue are unclear. The primary aim of this study was to test the hypothesis that mental fatigue exacerbates central fatigue induced by whole-body endurance exercise. Twelve subjects performed 30 min of either an incongruent Stroop task to induce a condition of mental fatigue or a congruent Stroop task (control condition) in a random and counterbalanced order. Both cognitive tasks (CTs) were followed by a whole-body …

Metalloproteinases and Tissue Inhibitors in Generalized Myasthenia Gravis. A Preliminary Study

2022

Introduction: Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have recently been proposed as promising biomarkers in different immune-mediated disorders. We evaluated the plasma levels of MMP-9 and MMP-2 and their tissue inhibitors TIMP-1 and TIMP-2 in a patients’ cohort with generalized myasthenia gravis (MG). Methods: Plasma concentrations of MMP-9, MMP-2, TIMP-1 and TIMP-2 were evaluated in 14 patients with generalized MG and 13 age- and sex-matched healthy controls. The severity of disease was assessed by the modified Osserman classification. Results: Compared to the healthy subjects, MG patients had increased plasma concentrations of MMP-9, but redu…

Acción del sugamadex y de los bloqueantes neromusculares: rocuronio y vecuronio en neuronas en cultivo primario

2017

INTRODUCCIÓN: El ROCURONIO y VECURONIO son los relajantes musculares no despolarizantes BNMNP más usados en la práctica clínica. El SUGAMADEX es el fármaco utilizado como reversor de la relajación muscular producida por los bloqueantes neuromusculares citados. En el presente trabajo analizamos los efectos del SUGAMADEX, la implicación del colesterol en los mismos y el posible papel protector del ROCURONIO y VECURONIO en cultivos primarios de neuronas de rata. HIPÓTESIS: Debido a la introducción paulatina del fármaco SUGAMADEX en la clínica y de los bloqueantes neuromusculares tipo ROCURONIO y VECURONIO, nos planteamos si estos fármacos o su combinación podrían ocasionar muerte neuronal en c…

Effects of 10 weeks of military training on neuromuscular function in non-overreached and overreached conscripts

2019

The purpose of the study was to examine how military training influences neuromuscular function in non-overreached and overreached conscripts. A total of 24 male conscripts participated in the study (8 weeks basic training + 2 weeks specialized training). All measurements were conducted during weeks 1, 5, 8 and 10. After the training period, non-overreached (NOR, n = 16) and overreached (OR, n = 8) groups were compared. Isometric maximal forces (bench press, elbow flexion and knee extension), single twitch (plantar flexors), H-reflex, M-wave (Hmax/Mmax) and V-wave (V/Mmax) (soleus) were measured. In knee extension, force production increased in NOR by 22.5 ± 20.5% (p  0.05). In OR, plantarf…

Power Loading-Induced Fatigue is Influenced by Menstrual Cycle Phase

2022

Purpose To examine the effects of fatiguing power-loading on neuromuscular properties, force production, and metabolic capacities during four phases of the menstrual cycle (MC); menstruation (M), mid-follicular (mid FOL), ovulation (OV), and mid-luteal (mid LUT). Methods Sixteen eumenorrheic women performed sessions of maximal explosive leg press (2x10 at 60%1RM load with 2 min recovery between sets). Serum hormones and neuromuscular responses were measured. Results The loading protocol significantly decreased power (between -14.2% and -12.5%; p < 0.001) and maximal force production (between MVC; -15.0% and -7.8%; p < 0.001–0.05), while decreasing activation level (between AL; -6.9% and -2.…

Physiological and Molecular Adaptations to Strength Training

2019

High muscle contraction forces that lead to gains in muscle function, size, and strength characterize resistance exercise training. The purpose of this chapter is to outline the adaptations in myofiber size and metabolism that occur by stimuli of hormones and local growth factors, mechanical and metabolic stress of muscle tissue, and myofibrillar disruptions induced by a resistance exercise bout. The chapter will highlight the network of intracellular pathways (including mTOR signaling) that ultimately lead to increases in gene expression and protein synthesis. Accumulation of acute exercise responses by systematic training over time modulate the muscle proteome that can be observed as chan…

Kuparin, hopean ja palladiumin talteenotto piirilevyjätteestä

2017

Tutkielmassa käsitellään rikkihapon käyttöä sähkö- ja elektroniikkaromuun kuuluvan piirilevyjätteen liuotuksessa ja rikkihappoon liuenneiden metallien talteenottoa erilaisin menetelmin. Sähkö- ja elektroniikkaromu on pian maailman suurimmaksi kasvava jätevirta, jolla on sekä ympäristöllisiä että taloudellisia vaikutuksia, jos romun sisältämiä metalleja ei saada kierrätettyä. Elektroniikkalaitteiden piirilevyt sisältävät noin 60 % metalleja, joiden talteenottamiseksi on lähiaikoina tehty paljon tutkimusta. Piirilevyjen sisältämiä arvokkaita metalleja ovat erityisesti kulta, hopea, palladium ja platina. Rikkihappo on yleisin teollisuudessa käytetty happoliuotin, …

Minoritāšu tiesību aizsardzība: Romu tautības tiesību ģenēze un evolūcija Latvijas Republikā

2018

Romi ir diskriminētākā minoritāte Latvijā, viņu tiesiskais stāvoklis ir aktuāla problēma arī mūsdienās. Darba mērķis ir analizēt minoritāšu tiesību aizsardzību Latvijas Republikā, padziļināti pētot romu tautības cilvēku tiesības. Darbā secināts, ka Latvijas tiesību sistēma paredz minoritāšu tiesību aizsardzību, bet, romu zemās izglītības dēļ, tiesību normas nesasniedz tiesību subjektu, tāpēc netiek pilnvērtīgi sasniegts mērķis – aizsargāt minoritātes. Latvijas Republikas demokrātiskajā režīmā valsts rūpējās par minoritāšu tiesisko aizsardzību, bet autoritārajā režīmā visa valsts uzmanība tika vērsta tikai uz latviešu nāciju. Minoritāšu (t.sk. romu) tiesības tika atjaunotas, sagrūstot autori…