Search results for "S5"
showing 10 items of 201 documents
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line.
1999
An estimated 170 million persons worldwide are infected with hepatitis C virus (HCV), a major cause of chronic liver disease. Despite increasing knowledge of genome structure and individual viral proteins, studies on virus replication and pathogenesis have been hampered by the lack of reliable and efficient cell culture systems. A full-length consensus genome was cloned from viral RNA isolated from an infected human liver and used to construct subgenomic selectable replicons. Upon transfection into a human hepatoma cell line, these RNAs were found to replicate to high levels, permitting metabolic radiolabeling of viral RNA and proteins. This work defines the structure of HCV replicons funct…
The Ontogenesis of Action Syntax
2019
Language and action share similar organizational principles. Both are thought to be hierarchical and recursive in nature. Here we address the relationship between language and action from developmental and neurophysiological perspectives. We discuss three major aspects: The extent of the analogy between language and action; the necessity to extend research on the yet largely neglected aspect of action syntax; the positive contribution of a developmental approach to this topic. We elaborate on the claim that adding an ontogenetic approach will help to obtain a comprehensive picture about both the interplay between language and action and its development, and to answer the question whether th…
The Effects of Banning Smartphone Use During Lectures in High Schools : An explanatory case study
2021
Master's thesis in Information systems (IS501) Research context–During the last decade, smartphonehas become an integral part of our lives. It is undeniable that the smartphone has impacted almost every aspect of our lives, and education is no exception. Banning smartphone use is one of the measures that has been implemented in high school to manage excessive smartphone use among students. Developing an appropriate policy to manage smartphone use during lectures can be a difficult task, because it can have a positive impact on their attention and academic performance, while also having a negative impact on their behavior and mentality. Purpose-This study addresses the issue regarding smartp…
Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein.
2003
The hepatitis C virus (HCV) NS5A protein is highly phosphorylated by cellular protein kinases. To study how NS5A might be integrated in cellular kinase signalling, we isolated phosphoproteins from HuH-7 hepatoma cells that specifically interacted with recombinant NS5A protein. Subsequent mass spectrometry identified the adaptor protein amphiphysin II as a novel interaction partner of NS5A. Mutational analysis revealed that complex formation is primarily mediated by a proline-rich region in the C-terminal part of NS5A, which interacts with the amphiphysin II Src homology 3 domain. Importantly, we could further demonstrate specific co-precipitation and cellular co-localization of endogenous a…
New rotational levels in $^{186}$Re nucleus
2020
International audience; Excited levels of 186 Re have been studied using results of the single γ -ray spectra measurements following the thermal neutron capture reaction. Energies and intensities of more than 500 γ -transitions have been obtained with the high-resolution crystal diffraction spectrometer GAMS5 of ILL. Most of the obtained intense γ -transitions have been placed in the 186 Re level scheme. A number of new levels, as well as the depopulation for levels observed earlier in the 187 Re (p,d)186 Re reaction measurements have been proposed. Structure of 186 Re levels is interpreted in terms of two-quasiparticle plus rotor coupling model and compared with that of the neighbouring do…
Ungdom og e-demokrati : hvilke ønsker og forventninger har ungdom til e-demokrati?
2007
Masteroppgave i informasjonssystemer 2007 - Høgskolen i Agder, Kristiansand E-demokrati er et satsningsområde i offentlig sektor. Det har i Norge vært synkende deltagelse i valg både til Storting og kommunevalg ved de siste valgene. Ungdom i aldersgruppen 18 til 21 år har lavere oppslutning rundt valgene enn eldre aldersgrupper. Flere mener at e-demokrati kan bidra til å øke oppslutning rundt demokratiet og valgene. I denne sammenheng er ungdom en viktig målgruppe. Vi har sett nærmere på e-demokrati rettet mot ungdom. Målet for denne masteroppgaven har vært å forstå hvilke ønsker og forventninger ungdom har til informasjonssystemer innen for edemokrati. For å besvare dette spørsmålet har vi…
Heterogeneous effects of sustainable agriculture practices: micro-evidence from Malawi
2020
Abstract Are the effects of sustainable agricultural practices heterogeneous across agro-ecology and wealth in Malawi? Would a wealth-enhancing policy be associated with increased effectiveness of these practices? Focusing on a nationally representative set of Malawian agricultural households, the article answers the above questions by employing plot-level panel data matched with a set of geo-referenced rainfall and temperature records. The findings suggest a positive correlation between aggregate yield and the adoption of organic fertilizer. A similar result holds for legume intercropping and for hybrid seeds, which are associated to reductions in yield volatility between the two waves. Ne…
Using the Microcontroller and the PLC in a RPP Robot Control
2012
This paper presents some aspects regarding the possibility of combining microcontroller and programmable logic controller (PLC) for robot control. The RPP robot is designed and manufactured within the Faculty of Engineering from “Lucian Blaga” University of Sibiu, as a patent: BRAŢ TELESCOPIC, Nr. 112418 B1, Int.CI.6 B 25 J 18/02, from 17.02.1997. Classical systems for programming and control of industrial robot are based on numerical control equipment, developed around a PC. Programmable Logic Controllers (PLC) haves proven to be viable alternatives to driving machine tools, industrial systems and Robots. Microcontrollers as computers offer advantage due to programmable inputs and outputs …
Innføring av CRM i offentlig sektor
2007
Masteroppgave i informasjonssystemer 2007 - Høgskolen i Agder, Kristiansand Modernisering av offentlig sektor basert på informasjons- og kommunikasjonsteknologi (IKT) er i økende grad et fokusområde under begrepet e-forvaltning. Dette har ført til nye teknologiske muligheter og arbeidsmåter internt og eksternt mellom offentlige organisasjoner, næringslivet og innbyggere. Integrering av isolerte systemer til standardiserte og virksomhetsomfattende informasjonssystemer har potensiale til å samle informasjonsflyten i en organisasjon. Dette kan skape radikale endringer både fra et organisatorisk og et teknologisk perspektiv. Customer Relationship Management (CRM) er et konsept fra privat sektor…
Creating an ethernet communication between a Simatic S7-1200 PLC and Arduino Mega for an omnidirectional mobile platform and industrial equipment
2020
Abstract The degree of automation in the industry increases more and more every year, trying to reduce more and more or even eliminate the collaboration with the human operator. The basis of all automatic industrial equipment is PLCs. This paper presents a method of extending the number of inputs and outputs of a Siemens Simatic S7-1200 PLC, using an Arduino Mega development board and an Ethernet communication. Following the realization of this communication, the number of inputs and outputs will increase considerably, being able to connect various sensors used for the construction of an omnidirectional mobile platform, but also for equipment for industry. The advantages of using this commu…