Search results for "SABR"
showing 10 items of 51 documents
Increased efficacy of stereotactic ablative radiation therapy after bevacizumab in lung oligometastases from colon cancer.
2018
Aim: Metastases from colorectal cancer are poorly responsive to stereotactic ablative radiation therapy (SABR) due to intratumoral hypoxia. Intratumoral oxygenation is improved by administration of angiogenesis inhibitors. Thus, there could be a clinical synergistic effect of SABR with bevacizumab on metastases from colorectal cancer. The aim of this study was to evaluate the feasibility and efficacy of SABR after bevacizumab in lung oligometastases from colon cancer. Methods: The data of patients with lung metastases from colon cancer who underwent SABR were retrospectively evaluated according to the following inclusion criteria: number of metastases ≤3; lung oligometastases from colon can…
L'anfiteatro
2017
Descrizione dell'anfiteatro di Sabratha e breve sunto della storia degli studi del monumento, all'interno della nuova guida della città.
Nuove ricerche sull'anfiteatro di Sabratha
2013
L'anfiteatro di Sabratha è uno degli edifici più importanti e noti della città tripolitana. Scavato e restaurato tra il 1924 e il 1926 dalla missione italiana diretta da Renato Bartoccini era rimasto sostanzialmente non studiato e non pubblicato. A partire dal 2009 è stato oggetto di un nuovo studio che muovendo da un nuovo accurato rilievo ha cercato di mettere a fuoco le caratteristiche salienti del monumento, proponendo anche un'ipotesi ricostruttiva. Prendendo le mosse dalla storia degli studi e dall'analisi delle strutture ancora esistenti, avvalendosi dei risultati di alcuni piccoli saggi stratigrafici, si è proceduto alla stesura di un catalogo degli elementi architettonici e delle t…
A Multicenter Large Retrospective Database on the Personalization of Stereotactic Ablative Radiotherapy for Lung Metastases From Colon-Rectal Cancer:…
2021
PURPOSE/OBJECTIVE(S): stereotactic ablative radiotherapy (SABR) has been shown to increase survival rates in oligometastatic disease (OMD), but local control of colorectal metastases still remains poor. We aimed to identify potential predictive factors of SBRT response through a multicenter large retrospective database and to investigate how lung SBRT can impact on the progression to the polymetastatic disease (PMD). MATERIALS/METHODS: the study involved 22 centers, and was approved by the Ethical Committee (Prot. Negrar 2019-ZT). 1023 lung metastases treated with SBRT in 622 patients were reported. The median BED was 105 Gy10. Lesion diameter GTV, PTV volume, dose, fractionations, and site…
Cone-beam computed tomography in lung stereotactic ablative radiation therapy: predictive parameters of early response
2016
To analyze lung lesion volume variations by contouring on cone-beam CT (CBCT) images to evaluate the early predictive parameters of stereotactic ablative radiation therapy (SABR) treatment response.The prescribed dose of SABR was varied according to the tumour site (central or peripheral) and maximum diameter of the lesions by using a strategy of risk-adapted dose prescription with a dose range between 48 and 70 Gy in 3-10 consecutive fractions. For the purpose of the analysis, the gross tumour volume (GTV) was recontoured for each patient at first and last CBCT using two lung levels/windows: (a) -600/1000 HU and (b) -1000/250 HU. Univariate analysis was performed to evaluate a correlation …
Konstantīna Čakstes piemiņas plāksnes atklāšanas fotogrāfija
2023
Rakstā tiek skaidrota LU prof. Konstantīna Čakstes piemiņas tradīcijas uzsākšana LU, skaidrojot tā cēloņus (K. Čakstes kapavietas atklāšana), norisi (K. Čakstes piemiņas plāksnes atklāšana) un sekas (K. Čakstes piemiņas kopšana un tā labums LU Muzejam kā pētnieciskai atmiņu institūcija). Par raksta pamatu izvēlēta vēsturiska fotogrāfija, kurā attēlota K. Čakstes piemiņas plāksnes atklāšana, taču izmantots arī citu avotu un literatūras klāsts raksta sagatavošanā. Raksts sagatavots Latvijas valsts un LU 105 gadu jubileju ietvaros, kas mijas kopā ar pašreizējo starptautisko spriedzi - Krievijas-Ukrainas kara eskalāciju.
Stereotactic Ablative Radiation Therapy for Lung Oligometastases: Predictive Parameters of Early Response by (18)FDG-PET/CT
2017
Abstract Objectives The objective of this study was to investigate fludeoxyglucose F 18 positron emission tomography/computed tomography ( 18 FDG-PET/CT) parameters as predictive of response after stereotactic ablative radiotherapy (SABR) for lung oligometastases. Methods The inclusion criteria of the current retrospective study were as follows: (1) lung oligometastases treated by SABR, (2) presence of 18 FDG-PET/CT before and after SABR for at least two subsequent evaluations, (3) Karnofsky performance status higher than 80, and (4) life expectancy longer than 6 months. All patients were treated with a biologically equivalent dose of at least 100 Gy with an alpha/beta ratio of 10. The foll…
Hlorēto parafīnu un bromēto antipirēnu noteikšana apkārtējās vides paraugos no Svalbāras, izmantojot augstas izšķirtspējas masspektrometriju
2022
Maģistra darbā ir apkopota informācija bromēto antipirēnu un hlorēto parafīnu izmantošanas vēsturi, īpašībām un izplatības dinamiku līdz polāriem reģioniem, ar fokusu uz heksabromciklododkānu. Papildus, tika apkopota informācijā no literatūras par šo savienojumu sastopamību apkārtējās vides paraugos no Arktikas un Antarktīdas. Iepriekš izstrādāta paraugu sagatavošanas metode eksperimentālā daļā tika optimizēta, izvērtējot izvēlēto fāžu efektivitāti bromēto antipirēnu frakcionēšanai. Paraugu sagatavošanas procedūru pielietoja paraugos esošu piesārņotāju profilu raksturošanai un daudzumu noteikšanai Eiropas Arktikas izcelsmes augsnes paraugos.
Edilizia privata a Sabratha. Per una riedizione delle pitture parietali di età romana
2016
Nel quadro delle ricerche sull’architettura residenziale, che rientrano nel progetto di pubblicazione dei vecchi scavi italiani a Sabratha della Missione archeologica dell’Università di Palermo, è stata avviata la riedizione delle pitture parietali rinvenute nella Casa di Leda (Regio II, ins. 6) e in quella dell’Attore tragico (Regio V, ins. 3), esposte dopo il restauro nel Museo di Sabratha. Sono già state pubblicate le pitture della Casa di Leda e la più conservata delle tre pareti provenienti dalla Casa dell’Attore tragico. Tra gli obiettivi della ricerca, di primario interesse è la revisione della cronologia tradizionale degli affreschi e lo studio delle caratteristiche delle botteghe s…
Temple Architecture
2017
Si esamina l'architettura religiosa di età romana imperiale a Sabratha partendo da un'analisi dei singoli edifici templari, con considerazioni di ordine tipologico e cronologico, valutando i riflessi sull'urbanistica della città. The Roman religious architecture of the Imperial period at Sabratha is examined, moving from an analysis of each building, with considerations about the tipology and the chronology of the buildings and evaluating the consequences on the city's urbanism.