Search results for "SAC"

Hyperthermia Enhances CD95-Ligand Gene Expression in T Lymphocytes

2004

Abstract Hyperthermia represents an interesting therapeutic strategy for the treatment of tumors. Moreover, it is able to regulate several aspects of the immune response. Fas (APO-1/CD95) and its ligand (FasL) are cell surface proteins whose interaction activates apoptosis of Fas-expressing targets. In T cells, the Fas-Fas-L system regulates activation-induced cell death, is implicated in diseases in which lymphocyte homeostasis is compromised, and plays an important role during cytotoxic and regulatory actions mediated by these cells. In this study we describe the effect of hyperthermia on activation of the fas-L gene in T lymphocytes. We show that hyperthermic treatment enhances Fas-L-med…

Description of Hysteresis in Lithium Battery by Classical Preisach Model

2012

In this paper Preisach Model is applied to obtain a mathematical model of the hysteresis in lithium battery. Preisach Model allows to describe the hysteresis of charging and discharging cycles in a lithium battery. The identification of the model is obtained by using a neural network technique developed for magnetic systems. The model is verified on some experimental tests on commercial batteries.

Kawalerzysta, dowódca i wykładowca - szkic do biografii gen. bryg. Konstantego Druckiego-Lubeckiego (1893-1940)

2018

Celem przeprowadzonych badań było opracowanie rozszerzonego szkicu biograficznego księcia gen. bryg. Konstantego Druckiego-Lubeckiego. Dzięki zebranym dokumentom i materiałom ustalono najważniejsze fakty z życia generała, dotyczące jego pochodzenia, nauki w Cesarskim Aleksandrowskim Liceum (Lycee Imperial Alexandre) w Petersburgu, udziału w walkach o niepodległość Polski oraz kariery w kawalerii i szkolnictwie wojskowym II RP. Udostępnione przez bliskich księcia materiały, skonfrontowane ze źródłami urzędowymi i dostępnymi publikacjami, pozwoliły także na ustalenie dodatkowych okoliczności związanych z jego śmiercią z rąk NKWD w 1940 roku. Dokumenty te umożliwiły rekonstrukcję podejmowanych…

Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles

2014

Núria Mas,1–3 Irene Galiana,3 Silvia Hurtado,† Laura Mondragón,1–3 Andrea Bernardos,1–3 Félix Sancenón,1–3 María D Marcos,1–3 Pedro Amorós,4 Nuria Abril-Utrillas,5 Ramón Martínez-Máñez,1–3 José Ramón Murguía1,3 1Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Centro Mixto Universidad Politécnica de Valencia, Universidad de Valencia, Valencia, Spain; 2Departamento de Química, Universidad Politécnica de Valencia, Valenci…

Production of microalgal external organic matter in a Chlorella-dominated culture: influence of temperature and stress factors

2020

[EN] Although microalgae are recognised to release external organic matter (EOM), little is known about this phenomenon in microalgae cultivation systems, especially on a large scale. A study on the effect of microalgae-stressing factors such as temperature, nutrient limitation and ammonium oxidising bacteria (AOB) competition in EOM production by microalgae was carried out. The results showed non-statistically significant differences in EOM production at constant temperatures of 25, 30 and 35 degrees C. However, when the temperature was raised from 25 to 35 degrees C for 4 h a day, polysaccharide production increased significantly, indicating microalgae stress. Nutrient limitation also see…

FTIR and SAXS study on MBCO-saccharide amorphous systems: protein-matrix reciprocal effects

2010

Structure and function of the vacuolar Ccc1/VIT1 family of iron transporters and its regulation in fungi

2020

Iron is an essential micronutrient for most living beings since it participates as a redox active cofactor in many biological processes including cellular respiration, lipid biosynthesis, DNA replication and repair, and ribosome biogenesis and recycling. However, when present in excess, iron can participate in Fenton reactions and generate reactive oxygen species that damage cells at the level of proteins, lipids and nucleic acids. Organisms have developed different molecular strategies to protect themselves against the harmful effects of high concentrations of iron. In the case of fungi and plants, detoxification mainly occurs by importing cytosolic iron into the vacuole through the Ccc1/V…

Cycles of time in the Iberian culture: the astronomical orientation of the temple of El Tossal de Sant Miquel de Llíria

2006

We present an archaeoastronomical study of the temple of the Iberian settlement of El Tossal de Sant Miquel de Llíria (València). We find that the major axis of the building is oriented very close to the east-west cardinal axis. The entrance of the temple is pointing towards an outstanding mountain on the eastern horizon, where the sunrise around the equinoxes takes place. On the other hand, the absence of other constructions just in front of the cultic building seems to support the inference that the astronomical relation was intentional, because it would permit the observation of the sunrise from the temple. The existence of other nearby Iberian sanctuaries showing similar relations with …

Cycles of time in the Iberian culture: the astronomical orientation of the temple of El Tossal de Sant Miquel de Llíria

2006

We present an archaeoastronomical study of the temple of the Iberian settlement of El Tossal de Sant Miquel de Llíria (València). We find that the major axis of the building is oriented very close to the east-west cardinal axis. The entrance of the temple is pointing towards an outstanding mountain on the eastern horizon, where the sunrise around the equinoxes takes place. On the other hand, the absence of other constructions just in front of the cultic building seems to support the inference that the astronomical relation was intentional, because it would permit the observation of the sunrise from the temple. The existence of other nearby Iberian sanctuaries showing similar relations with …

Farmaceitisko vielu ekotoksiskuma riska novērtējums uz mikroorganismiem notekūdeņos

2017

Vides piesārņojums ar AFV šobrīd ir aktuāla problēma un ir nepieciešamas zināšanas par iespējamajām šī piesārņojuma sekām. Darba mērķis bija pētīt baktēriju P.fluorescens AM 11 un M.luteus fizioloģiskās atbildes reakciju uz dažādu farmaceitisko vielu klātbūtni, kā arī novērtēt kā paaugstinātas ibuprofēna koncentrācijas ietekmē aktīvo dūņu baktēriju sabiedrības daudzveidību un antibiotiku rezistences veidošanos. Antibiotika ciprofloksacīns uzrāda visspēcīgāko inhibējošo efektu uz P.fluorescens AM 11 un M.luteus baktēriju kultūrām periodiskā kultūrā mikroplatēs. Augstas ibuprofēna koncentrācijas aktīvajāss dūņās veicina Sphingomonadales un Enterobacteriales kārtas baktēriju attīstību un uzrād…