Search results for "SAC"

showing 10 items of 3337 documents

Physico-chimie des lipopolysaccharides et réponse inflammatoire : rôle des lipoprotéines

2014

LPS is a potent bacterial pro-inflammatory agent, consisting of hydrophilic, polysaccharide part and of a lipid A which is considered like active moiety. Nevertheless, the O chain of LPS influences their aggregation in aqueous media. Therefore, our goal has been to determine the role of O chain on the LPS biological and physiopathological effects. Our work was organized according to three main axes, and led to the following findings :- development of a new LPS assay by LC-MS/MS. The combination of this new technique with LAL test allowed us to calculate an inactivation ratio which reflects the ability of host organism to inactivate LPS, especially through their transfer to HDL by PLTP. The …

Innate immunityInflammationImmunité innéeTLR4 (Toll-Like Receptor 4)Lipopolysaccharide (LPS)Monocyte[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Lipide ALipoprotéinePhosphoLipid Transfer Protein (PLTP)Aggregation[ SDV.BBM.BC ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Agrégationlipids (amino acids peptides and proteins)[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]LC-MS/MS assayDosage LC-MS/MSLipoprotein[SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Protéine de Transfert des Phospholipides (PLTP)
researchProduct

Decomposition studies of group 6 hexacarbonyl complexes. Part 1: Production and decomposition of Mo(CO)6 and W(CO)6

2015

Abstract Chemical studies of superheavy elements require fast and efficient techniques, due to short half-lives and low production rates of the investigated nuclides. Here, we advocate for using a tubular flow reactor for assessing the thermal stability of the Sg carbonyl complex – Sg(CO)6. The experimental setup was tested with Mo and W carbonyl complexes, as their properties are established and supported by theoretical predictions. The suggested approach proved to be effective in discriminating between the thermal stabilities of Mo(CO)6 and W(CO)6. Therefore, an experimental verification of the predicted Sg–CO bond dissociation energy seems to be feasible by applying this technique. By in…

Inorganic chemistryMetal carbonyl02 engineering and technology010402 general chemistry01 natural sciences7. Clean energythermal stability540 ChemistryseaborgiumThermal stabilityNuclideGas compositionPhysical and Theoretical Chemistrycarbonyl complexegroup 6ChemistrytransactinideTransition metals021001 nanoscience & nanotechnologyDecompositionBond-dissociation energy0104 chemical sciencesVolumetric flow rateYield (chemistry)570 Life sciences; biologyPhysical chemistry0210 nano-technology
researchProduct

A novel target of lithium therapy.

2000

Phosphatases converting 3'-phosphoadenosine 5'-phosphate (PAP) into adenosine 5'-phosphate are of fundamental importance in living cells as the accumulation of PAP is toxic to several cellular systems. These enzymes are lithium-sensitive and we have characterized a human PAP phosphatase as a potential target of lithium therapy. A cDNA encoding a human enzyme was identified by data base screening, expressed in Escherichia coli and the 33 kDa protein purified to homogeneity. The enzyme exhibits high affinity for PAP (K(m)1 microM) and is sensitive to subtherapeutic concentrations of lithium (IC(50)=0.3 mM). The human enzyme also hydrolyzes inositol-1, 4-bisphosphate with high affinity (K(m)=0…

Inositol-14-bisphosphateDNA ComplementaryBicinePhosphataseMolecular Sequence DataBiophysicschemistry.chemical_elementSaccharomyces cerevisiaeLithiummedicine.disease_causeBiochemistrychemistry.chemical_compoundStructural BiologyNucleotidasesComplementary DNAPhosphataseGeneticsmedicineEscherichia coliHumansAmino Acid SequenceCloning MolecularMolecular BiologyEscherichia coliIC50Chromatography High Pressure Liquidchemistry.chemical_classificationExpressed Sequence TagsBase Sequence3′-Phosphoadenosine 5′-phosphateCell BiologyMolecular biologyAdenosineAdenosine MonophosphatePhosphoric Monoester HydrolasesAdenosine DiphosphateEnzymechemistryBiochemistryLithiummedicine.drugHumanFEBS letters
researchProduct

Capitols de la insaculacio de la ... Ciutat de Valencia, concedits per la S.C.R.M. del Rey ... en 24 de Març any 1648 / manats imprimir en lo any MD…

1652

Port. orlada amb l'escut xil. de la Ciutat de València Caplletra ornada Sign.: A8 Reclams

Insaculació Valencia (Comunitat valenciana) S. XVII Obres anteriors a 1800
researchProduct

Privilegis. 1633 - 1638

Inclou els privilegis de insaculació datats el 20 de octobre de 1633, 18 de novembre de 1633 i 22 de mars de 1638 Frisos, caplletres ornades Sign.: [ ]1, A8, B4 Port. amb esc. xil. de la ciutat de Valencia y con orla tip Port. amb orla tip Postil·les. - Reclams

Insaculació Comunitat Valenciana S. XVII Obres anteriors al 1800Municipis Govern i administració Comunitat Valenciana S. XVII Obres anteriors al 1800
researchProduct

Sobre el orden seguido en el ritual de Cabeço das Fraguas y la naturaleza de las HOSTIAE y VICTIMAE en él ofrecidas y sacrificadas

2018

Este trabajo trata sobre la naturaleza de las víctimas en el ritual indoeuropeo y la estructura sintáctica de la inscripción lusitana de Cabeço das Fraguas (Portugal), proponiendo una nueva lectura de una de las palabras del texto. This paper about the Indo-European ritual sacrifice in lusitanian inscription of Cabeço das Fraguas propose a new reading and interpretation of the text.

Inscripcions antigueslengua lusitana; suovetaurilia; sacrificios indoeuropeos.lengua lusitanasuovetauriliasacrificios indoeuropeos.
researchProduct

Molecular characterization of a male-specific glycosyl hydrolase, Lma-p72, secreted on to the abdominal surface of the Madeira cockroach Leucophaea m…

2003

0264-6021 (Print) Journal Article Research Support, Non-U.S. Gov't; The epicuticular surface protein Lma-p72 is specific to the abdominal secretions of Leucophaea maderae (Madeira cockroach) adult males. Natural Lma-p72 was purified and the complete cDNA sequence determined by reverse-transcription PCR using primers based on Edman degradation fragments. Northern blot and in situ hybridization analyses showed that Lma-p72 was expressed in the tergal and sternal glands. Sequence alignment indicates that Lma-p72 is closely related to the family 1 glycosyl hydrolases (EC 3.2.1). Native Lma-p72 was proved to be active in the abdominal secretions and exhibit a beta-galactosidase-like activity. Ho…

Insect Proteins/*genetics/secretionMaleOligosaccharidesCockroachesRecombinant Proteins/chemistryBiochemistryPolymerase Chain ReactionEpitheliumPheromonesLactoneschemistry.chemical_compoundGlycoside Hydrolases/*genetics/secretionGlycoside hydrolaseNorthernCockroaches/*genetics/metabolismIn Situ HybridizationOligosaccharides/metabolismbiologyBlottingRecombinant ProteinsBiochemistryExocrine Glands/enzymologyLarvaInsect ProteinsHydrocarbons/pharmacologyFemaleResearch ArticleDNA ComplementaryGlycoside HydrolasesMolecular Sequence DataSequence alignmentComplementary/geneticsGluconatesExocrine GlandsComplementary DNAbiology.animalHydrolaseAnimalsGlycosylMolecular BiologyCockroachEpithelium/physiologyPheromones/chemistry/metabolismEdman degradationBiological TransportCell BiologyDNABlotting Northernbeta-Galactosidasebiology.organism_classificationMolecular biologyHydrocarbonsGluconates/pharmacologyBlaberidaechemistrybeta-Galactosidase/metabolism
researchProduct

Synergism and Antagonism between Bacillus thuringiensis Vip3A and Cry1 Proteins in Heliothis virescens, Diatraea saccharalis and Spodoptera frugiperda

2014

Made available in DSpace on 2015-03-18T15:56:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-10-02Bitstream added on 2015-03-18T16:28:28Z : No. of bitstreams: 1 WOS000342591500006.pdf: 270331 bytes, checksum: c280e3f5bc5e3bb0b92bf74d046135f0 (MD5) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Spanish Ministry of Economy and Competivity FEDER Second generation Bt crops (insect resistant crops carrying Bacillus thuringiensis genes) combine more than one gene that codes for insecticidal proteins in the same plant to provide better control of agricultural pests. Some of the new combinations involve co-expression of cry and vip genes. Because Cry and Vip proteins …

InsecticidesBacillus thuringiensislcsh:MedicineSpodopteraSpodopteraDiatraea saccharalisHemolysin ProteinsLepidoptera genitaliaHemolysin ProteinsBacterial ProteinsBacillus thuringiensisBotanyGeneticsEscherichia coliAnimalslcsh:ScienceMolecular BiologyMultidisciplinarybiologyHeliothis virescensBacillus thuringiensis Toxinslcsh:RfungiBiology and Life SciencesAgriculturebiology.organism_classificationEndotoxinsLepidopteraBiochemistryCry1AcLarvalcsh:QElectrophoresis Polyacrylamide GelPest ControlAntagonismZoologyEntomologyResearch ArticleBiotechnologyProtein BindingPLoS ONE
researchProduct

Technique and results of the retroperitoneoscopic adrenalectomy via a lumbar approach

1998

Introduction: Since 1992, endoscopic techniques have been used increasingly in adrenal-gland surgery. In the present paper, the technique of the retroperitoneoscopic adrenalectomy via a lumbar approach is described. Methods: The patient is placed in a lateral decubitus position. In the first step, a dilatation trocar is introduced in the retroperitoneal space to create an artificial cavity. The dilatation trocar is replaced by a blocking trocar to close off the operating field. After insufflation of CO2, two additional trocars are introduced in the area of the conventional flank incision. Adrenalectomy is performed via these ports. Once the adrenal gland is completely mobilized, it is inser…

Insufflationmedicine.medical_specialtybusiness.industryAdrenalectomymedicine.medical_treatmentLumbosacral RegionAdrenalectomyEndoscopyFlank incisionSurgeryTreatment Outcomemedicine.anatomical_structureCardiothoracic surgeryLateral Decubitus PositionmedicineLumbar approachHumansRetroperitoneal spaceSurgeryRetroperitoneal SpacebusinessAbdominal surgeryLangenbeck's Archives of Surgery
researchProduct

Primacía epistémica en géneros interaccionales: atenuación, intensificación y territorio

2018

En la última década, ha surgido dentro del Análisis Conversacional una corriente teórica en torno al concepto de primacía epistémica en interacción, dentro de la cual se concibe la transmisión de información como una cuestión de territorio. En este trabajo, se analizan secuencias de aserciónacuerdo en conversaciones y entrevistas con el fin de mostrar que los mecanismos de atenuación e intensificación empleados por los hablantes funcionan como huellas de la interpretación que hacen los interlocutores de la situación en términos de posicionamiento epistémico. Se argumenta que existen casos de congruencia epistémica –cuando los interlocutores convergen en su interpretación de la situación– y …

IntensificationLinguistics and LanguageMitigationLiterature and Literary Theorymedia_common.quotation_subjectAtenuaciónLanguage and LinguisticsEpistemologyNegotiationConversation analysisCongruence (geometry)Análisis de la ConversaciónIntensificaciónTerritory of informationTerritorio de la informaciónSociologyPrimacía epistémicaConversation AnalysisEpistemic primacymedia_commonRilce. Revista de Filología Hispánica
researchProduct