Search results for "SAF"

showing 10 items of 2183 documents

From job demands and resources to work engagement, burnout, life satisfaction, depressive symptoms, and occupational health

2016

This study investigated the cross-lagged associations between work engagement and burnout, and life satisfaction and depressive symptoms, their demands (i.e., workload) and resources (i.e., servant leadership, self-efficacy, resilience) and relationships with occupational health outcomes (i.e., recovery, number of mental health diagnoses, workaholism). This study is a part of an ongoing Occupational Health Study in which 1 415 employees (586 men, 829 women) were followed twice during two years 2011–12 through their occupational health services. The participants filled in a questionnaire on their work engagement, burnout symptoms, well-being, personal and work environmental resources and dem…

515 Psychologymedia_common.quotation_subjecttyön imueducationServant leadership050109 social psychologyBurnoutresurssitOccupational safety and health0502 economics and businessBurnout0501 psychology and cognitive sciencesLIFE SATISFACTIONta512ta515media_commonservant leadershipOccupational healthjob demands and resourcestyöterveysWork engagement05 social sciencesPublic Health Environmental and Occupational HealthLife satisfactionWorkloadMental healthLife SatisfactionPsychiatry and Mental healthjob demandsWork engagementJob demands and resiources8. Economic growthWORK ENGAGEMENTBURNOUTPsychological resiliencePsychologyresourcesServant leadershipSocial psychology050203 business & managementpsychological phenomena and processesClinical psychology
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Combined Innovation Policy: Linking Scientific and Practical Knowledge in Innovation Systems

2012

New research indicates that firms combining the science-based STI (Science, Technology, Innovation) and the experience-based DUI (Doing, Using, Interacting) modes of innovation are more efficient when it comes to improving innovation capacity and competitiveness. With regard to innovation policy, the STI mode calls for a supply driven policy, typically aimed to commercialise research results. The DUI mode suggests a demand driven policy approach, such as supporting the development of new products or services to specific markets. This paper analyses how the two types of innovation policy and the two innovation modes can be combined in regional innovation systems. The analysis builds on studi…

9. Industry and infrastructure05 social sciencesGeography Planning and Development0211 other engineering and technologiesInnovation management021107 urban & regional planning02 engineering and technologyPolicy initiativesInnovation policy Regional system of innovation Modes of innovation Food industry Agribusiness Farm Management Food Consumption/Nutrition/Food Safety Industrial Organization Research Methods/ Statistical Methods0502 economics and businessEconomicsMarketing050203 business & managementIndustrial organizationAgribusiness
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Derecho de acceso a la información : el desafío de una sociedad guiada por la transparencia en el ordenamiento jurídico español

2021

This study will address the two aspects of rights linked to information, the right to information and the right to information, to end with the formulation of some conclusions that, distancing themselves from a mere summary, seek to encourage doctrinal and political debate on assumptions that, being peacefully settled, should be reformulated in light of the repeated crisis of transparency. For this, it will be articulated by addressing, first, the most significant aspects of the right to information and its link with the right to freedom of expression, as well as the new challenges that these rights face in the digital age, to then analyze the right to information, its regulation in the Spa…

:CIENCIAS JURÍDICAS [UNESCO]the right to information and the right to informationbeing peacefully settledto then analyze the right to informationshould be reformulated in light of the repeated crisis of transparency. For this2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055240 Derecho de acceso a la información el desafío de una sociedad guiada por la transparencia en el ordenamiento jurídico español Alonso GarcíaTransparencydistancing themselves from a mere summaryexpress mention will be made of transparency from the perspective of political information. Transparencialibertad de expresiónthe most significant aspects of the right to information and its link with the right to freedom of expressionderecho a/de la informaciónUNESCO::CIENCIAS JURÍDICASseek to encourage doctrinal and political debate on assumptions thatbuen gobiernofreedom of expressionright to informationits regulation in the Spanish legal system and the doctrinal debate about its consideration as a fundamental right. As the last point of this contributionas well as the new challenges that these rights face in the digital agegood governance 828 861firstit will be articulated by addressingNieves This study will address the two aspects of rights linked to informationto end with the formulation of some conclusions that
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Safety Evaluation of α-Lipoic Acid Supplementation: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Studies

2020

Alpha-lipoic acid (ALA) is a natural short-chain fatty acid that has attracted great attention in recent years as an antioxidant molecule. However, some concerns have been recently raised regarding its safety profile. To address the issue, we aimed to assess ALA safety profile through a systematic review of the literature and a meta-analysis of the available randomized placebo-controlled clinical studies. The literature search included EMBASE, PubMed Medline, SCOPUS, Google Scholar, and ISI Web of Science by Clarivate databases up to 15th August 2020. Data were pooled from 71 clinical studies, comprising 155 treatment arms, which included 4749 subjects with 2558 subjects treated with ALA an…

:Chemicals and Drugs::Pharmaceutical Preparations::Placebos [Medical Subject Headings]Physiologyα -lipoic acid ; thioctic acid ; dietary supplement ; safety ; meta-analysisClinical BiochemistryDisease030204 cardiovascular system & hematologyBiochemistrymeta-analysi:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants [Medical Subject Headings]Dietary supplementchemistry.chemical_compound0302 clinical medicinethioctic aciddietary supplement meta-analysis safety thioctic acid α-lipoic acid:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Clinical Trials as Topic::Controlled Clinical Trials as Topic::Randomized Controlled Trials as Topic [Medical Subject Headings]α-lipoic acidLipoic acidSafety profile:Publication Type::Study Characteristics::Meta-Analysis [Medical Subject Headings]Suplementos dietéticosMeta-analysis:Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements [Medical Subject Headings]SafetysafetyAlpha-lipoic acidmedicine.medical_specialtyMEDLINEÁcido tióctico030209 endocrinology & metabolismPlacebo:Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Thiophenes::Thioctic Acid [Medical Subject Headings]Article:Health Care::Environment and Public Health::Public Health::Accidents::Accident Prevention::Safety [Medical Subject Headings]03 medical and health sciencesα‐lipoic acidThioctic acidInternal medicineDiabetes mellitusmedicineMetaanálisisAdverse effectSeguridad:Diseases::Cardiovascular Diseases [Medical Subject Headings]Molecular Biology:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Volatile [Medical Subject Headings]business.industryRevisión sistemáticalcsh:RM1-950Cell Biologymedicine.disease:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Habits::Food Habits::Smoking [Medical Subject Headings]meta-analysisMeta-analysislcsh:Therapeutics. Pharmacologychemistry:Diseases::Nervous System Diseases [Medical Subject Headings]dietary supplementMeta‐analysisbusinessAntioxidants
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Efectos del alcohol y conducción de vehículos: creencias y conductas de los jóvenes

2002

Los accidentes de tráfico son una de las principales causas de mortalidad entre I y 45 años (Generalitat de Catalunya, 1992 ; Montoro, et al., 1995). Numerosos estudios constatan que la siniestralidad viaria está relacionada con el consumo de alcohol (Montoro, 1997). Este problema es especialmente importante en la población joven y se incrementa durante las madrugadas de los fines de semana (Pedragosa,1995; Summala y Mikkola, 1994). Algunos estudios ponen de manifiesto la falta de información y/o conocimientos de muchos jóvenes sobre la normativa vigente que regula el consumo de alcohol de los conductores, así como de los efectos de esta droga sobre el consu¬midor (Reppetto y Senra, 1997; T…

:PSICOLOGÍA::Psicofarmacología [UNESCO]Seguretat viària i joves:PSICOLOGÍA [UNESCO]Alcohol conducción creencias erróneasUNESCO::PSICOLOGÍAUNESCO::PSICOLOGÍA::PsicofarmacologíaTraffic safety and childrenConsum d'alcohol i accidents de circulacióDrinking and traffic accidents
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HUMAN SAFETY PERFORMANCE IN HIGH RELIABILITY ORGANIZATIONS: THE CASE OF THE NUCLEAR INDUSTRY

2018

Over the last few decades, the study of safety in high reliability organizations has not paid enough attention to the human role and its contribution to a reliable operation. Therefore, the literature about human safety performance is scarce and disjointed. The present paper integrates the existing knowledge on workers’ safety performance in high risk industries, specifically in the nuclear industry. In order to do this, we provide a literature review in which the concept of “safety performance” is clarified, and at the same time, we present the most recent research studies and models on this concept.

A- ccidents.lcsh:PsychologySafety performanceRisk managementNuclear power plantsHigh reliabilitylcsh:BF1-990Safety managementPapeles del Psicólogo
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Calibration of microscopic traffic simulation models for evaluating operation and safety performance at roundabouts

AIMSUN microsimulation roundabout genetic algorithmSSAM surrogate safety measureturbo-roundaboutsingle-lane roundabouts; double-lane roundabouts; turbo-roundabouts; entry capacity; operations; gap- acceptance parameters; Systematic Review; Meta-analysis; capacity uncertainty; AIMSUN microsimulation roundabout genetic algorithm; passenger car equivalent; SSAM surrogate safety measurecapacity uncertaintygap- acceptance parameteroperationsingle-lane roundaboutpassenger car equivalentSettore ICAR/04 - Strade Ferrovie Ed AeroportiMeta-analysiSystematic Reviewdouble-lane roundaboutentry capacity
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study.

2013

We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout perio…

ARN Bacterianoved/biology.organism_classification_rank.speciesPhysiologylcsh:Medicine:Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Ecosystem::Biodiversity::Biota::Microbiota [Medical Subject Headings]law.inventionFecesProbioticAntibioticslawLactobacillus:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Child Nutritional Physiological Phenomena::Infant Nutritional Physiological Phenomena::Breast Feeding [Medical Subject Headings]lcsh:Science:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::RNA::RNA Bacterial [Medical Subject Headings]BifidobacteriumMultidisciplinaryBifidobacterium brevebiologyLacticaseibacillus rhamnosusMicrobiotaHibridación in SituInterleukin-10:Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales::Lactobacillaceae::Lactobacillus [Medical Subject Headings]Breast FeedingBloodCytokinesFemaleResearch ArticleAdult:Anatomy::Fluids and Secretions::Feces [Medical Subject Headings]Lactobacillus paracasei:Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Clostridium::Clostridium difficile [Medical Subject Headings]Microbiology:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::Nucleic Acid Probes::Oligonucleotide Probes [Medical Subject Headings]Double-Blind MethodLactobacillus rhamnosusHumansImmunologic Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling::In Situ Hybridization [Medical Subject Headings]FecesSafety studiesved/biologyProbioticslcsh:RClostridium difficile:Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria::Bifidobacterium [Medical Subject Headings]biology.organism_classificationImmunoglobulin ALactobacilluslcsh:QInterleukin-4BifidobacteriumBreast feedingSondas de OligonucleótidosPLoS ONE
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Analysis of the U L3-edge X-ray absorption spectra in UO2 using molecular dynamics simulations

2017

This work was supported by a grant from the Swiss National Supercomputing Centre (CSCS) under the project ID s444. The resource allocation within the PSI share at CSCS and on the PSI compute cluster Merlin4 is also acknowledged. D. B. is grateful for a fellowship within the Sciex-NMS programme. A. K. was supported by Latvian Science Council Grant no. 187/2012.

Absorption spectroscopyUranium dioxideAb initioEnergy Engineering and Power Technologychemistry.chemical_elementNanotechnology02 engineering and technologyMolecular dynamics01 natural sciencesMolecular physicschemistry.chemical_compoundUranium dioxide0103 physical sciences:NATURAL SCIENCES:Physics [Research Subject Categories]Safety Risk Reliability and QualitySpectroscopyAbsorption (electromagnetic radiation)Waste Management and Disposal010302 applied physicsPhysicsX-ray absorption spectroscopyExtended X-ray absorption fine structureX-ray absorption spectroscopyUranium021001 nanoscience & nanotechnologyEXAFSNuclear Energy and Engineeringchemistry0210 nano-technologyCP2K
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