Search results for "SAF"

Sociāla reklāma un tās ietekme uz cilvēkiem

2016

Šīs darbs piedāvā informāciju un pētījumu par sociālo reklāmu un tās ietekmi uz cilvēkiem. Pētījuma mērķis ir noskaidrot cilvēku sajūtas un uztveri par sociālo reklāmu. Darbs sniedz informāciju par sociālo reklāmu, tās misiju, funkcijām un īsu vēsturi. Kritiskā diskursa analīze sniedz autores pētījumu par sociālo reklāmu, kas ir saistīta ar ģimenes vardarbību, ceļa drošību un ekoloģijas problēmām. Aptaujas analīze apraksta cilvēku viedokļus par sociālo reklāmu, kā arī viņu izjūtas un emocijas aplūkojot konkrētus sociālās reklāmas piemērus.

Ochrona porządku i bezpieczeństwa publicznego przez policję na przykładzie gminy Dąbrowa Górnicza

2017

Public order and safety is one of the priority tasks of the State and local government units. The safety of people and the maintenance of public order and security rests with the Police. The scope of activities and competence of this service regulated by an umber of legal acts. Police Headquarters in Dąbrowa Górnicza is an organizational unit of the Police constituting an auxiliary camera. Its activities are directly subject to the supervision of the Silesian Commander of Provincial Police. A police officer must perform their duties to the best of knowledge and will with due honesty and integrity. His duty is to respect human dignity and respect for and protection of human rights.

A novel device for assessing the health risk caused by hand-arm vibrations in olives harvesting

2012

The mechanization of olive harvesting is very important both to reduce the costs of production and to assure the oil quality because the manual harvest does not allow to operate at the right time and also need a long period to be completed. The use of portable shakers, that are spreading more than others typologies, can give a solution to the problem. However, the use of such equipment may involve risk of exposure to hand-transmitted vibration. The aim of this study was to assess the level of exposure to hand-arm vibration of the operators using portable shakers (reference standards UNI EN ISO 5349-1:2004, Italian Low Decree 81/2008). The research presented here concerns the definition of a…

Safety in the use of portable olive harvesters

2011

Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea

2019

Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…

Online interventions to prevent mental health problems implemented in school settings: the perspectives from key stakeholders in Austria and Spain

2021

Abstract Background Schools are key settings for delivering mental illness prevention in adolescents. Data on stakeholders’ attitudes and factors relevant for the implementation of Internet-based prevention programmes are scarce. Methods Stakeholders in the school setting from Austria and Spain were consulted. Potential facilitators (e.g. teachers and school psychologists) completed an online questionnaire (N=50), policy makers (e.g. representatives of the ministry of education and health professional associations) participated in semi-structured interviews (N=9) and pupils (N=29, 14–19 years) participated in focus groups. Thematic analysis was used to identify experiences with, attitudes a…

Immunogenicity and safety of a quadrivalent high-dose inactivated influenza vaccine compared with a standard-dose quadrivalent influenza vaccine in h…

2021

A quadrivalent high-dose inactivated influenza vaccine (IIV4-HD) is licensed for adults ≥65 y of age based on immunogenicity and efficacy studies. However, IIV4-HD has not been evaluated in adults aged 60–64 y. This study compared immunogenicity and safety of IIV4-HD with a standard-dose quadrivalent influenza vaccine (IIV4-SD) in adults aged ≥60 y. This Phase III, randomized, modified double-blind, active-controlled study enrolled 1,528 participants aged ≥60 y, randomized 1:1 to a single injection of IIV4-HD or IIV4-SD. Hemagglutination inhibition (HAI) geometric mean titers (GMTs) were measured at baseline and D 28 and seroconversion assessed. Safety was described for 180 d after vaccinat…

Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in De…

2020

Background: Registry studies broadly describing the safety of systemic drugs in psoriasis are needed. Objective: To describe the safety findings of the systemic drugs acitretin, adalimumab, apremilast, cyclosporine, etanercept, infliximab, methotrexate, secukinumab, and ustekinumab used for the treatment of moderate to severe psoriasis in patients included in the Spanish Registry of Adverse Events for Biological Therapy in Dermatological Diseases (BIOBADADERM) Registry. Methods: The incidence rate ratio (IRR) and adjusted IRR (including propensity scores) of identified adverse events for each drug, using methotrexate as reference, were determined by means of a prospective cohort. Results: O…

Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor

2020

Introduction: The discovery and the clinical availability of novel cyclin-dependent kinases 4 and 6 inhibitors have profoundly changed the therapeutic scenario of metastatic hormone receptor-positive breast carcinoma. Among these inhibitors, abemaciclib can induce potent and sustained cell cycle arrest and immune system stimulation. Areas covered: This review summarizes the safety profile and clinical efficacy data on abemaciclib alone or in combination with aromatase inhibitors or fulvestrant in metastatic hormone receptor-positive breast carcinoma. The management of patients treated with abemaciclib is the object of this paper. Expert opinion: As shown in phase 2 and 3 clinical trials on …

Positron production using a 9 MeV electron linac for the GBAR experiment

2020

For the GBAR (Gravitational Behaviour of Antihydrogen at Rest) experiment at CERN's Antiproton Decelerator (AD) facility we have constructed a source of slow positrons, which uses a low-energy electron linear accelerator (linac). The driver linac produces electrons of 9 MeV kinetic energy that create positrons from bremsstrahlung-induced pair production. Staying below 10 MeV ensures no persistent radioactive activation in the target zone and that the radiation level outside the biological shield is safe for public access. An annealed tungsten-mesh assembly placed directly behind the target acts as a positron moderator. The system produces $5\times10^7$ slow positrons per second, a performan…