Search results for "SAGE"
showing 10 items of 1373 documents
Are analysts doing method validation in liquid chromatography?
2014
International audience; Method validation is being applied in the reported analytical methods for decades. Even before this protocol was defined, authors already somehow validated their methods without full awareness. They wished to assure the quality of their work. Validation is an applied approach to verify that a method is suitable and rugged enough to function as a quality control tool in different locations and times. The performance parameters and statistical protocols followed throughout a validation study vary with the source of guidelines. Before single laboratory validation, an analytical method should be fully developed and optimized. The purpose of the validation is to confirm p…
Evaluation of DR and CR digital mammography systems based on phantom and breast dosimetry.
2006
Digital mammography has been progressively introduced in screening centers, since recent evolution of CR and DR detectors. However, it is questionable which exposure conditions would be more suitable when these techniques are applied, in order to reduce the glandular breast doses, as they are related with induced carcinogenesis. Several exposures have been performed in CR and DR mammography units for comparing absorbed doses during quality control assessments and during screening, diagnosis and treatment. In the first case, the CIRS11A mammographic phantom has been used with standard exposure conditions (28 kV, AEC mode with blackening +0, 50:50 glandularity and 4.5 compressed breast thickn…
Regards croisés sur l'école primaire française : éléments d'évaluation macro et micro
2007
07068; A partir de recherches récentes et en cours, nous nous interrogerons dans ce document sur la qualité de notre école primaire en mobilisant des analyses qui présentent une complémentarité visible sur deux plans. Sur le plan méthodologique et conceptuel en prenant en compte différents niveaux statistiques : le pays, la classe et l'élève ; cela permet de percevoir une image globale du fonctionnement de l'école et de mieux comprendre comment les différentes facettes du contexte scolaire interviennent sur les apprentissages des élèves. La complémentarité se situe également sur le plan théorique plusieurs disciplines étant réunies (économie, sociologie et psychologie) pour l'étude d'un mêm…
Design of a lambda configuration in artificial coherent nanostructures
2015
The implementation of a three-level Lambda System in artificial atoms would allow to perform advanced control tasks typical of quantum optics in the solid state realm, with photons in the $\mathrm{\mu m}$/mm range. However hardware constraints put an obstacle since protection from decoherence is often conflicting with efficient coupling to external fields. We address the problem of performing conventional STImulated Raman Adiabatic Passage (STIRAP) in the presence of low-frequency noise. We propose two strategies to defeat decoherence, based on "optimal symmetry breaking" and dynamical decoupling. We suggest how to apply to the different implementations of superconducting artificial atoms, …
Design of a Lambda system for population transfer in superconducting nanocircuits
2013
The implementation of a Lambda scheme in superconducting artificial atoms could allow detec- tion of stimulated Raman adiabatic passage (STIRAP) and other quantum manipulations in the microwave regime. However symmetries which on one hand protect the system against decoherence, yield selection rules which may cancel coupling to the pump external drive. The tradeoff between efficient coupling and decoherence due to broad-band colored Noise (BBCN), which is often the main source of decoherence is addressed, in the class of nanodevices based on the Cooper pair box (CPB) design. We study transfer efficiency by STIRAP, showing that substantial efficiency is achieved for off-symmetric bias only i…
Quantum plasmonics with multi-emitters: application to stimulated Raman adiabatic passage
2018
We construct a mode-selective effective model describing the interaction of the localised surface plasmon polaritons (LSPs) supported by a spherical metal nanoparticle (MNP) with N quantum emitters (QEs) in an arbitrary geometric arrangement. Simplifying previously presented procedures, we develop a formulation in which the field response in the presence of the MNP can be decomposed into orthogonal modes, expanding the Green tensor of the system in the spherical vector harmonics basis and using the generalized global Löwdin orthogonalization algorithm. We investigate the possibility of using the LSPs as mediators of an efficient control of population transfer between two QEs. We show that a…
Biowaiver monographs for immediate release solid oral dosage forms: quinidine sulfate.
2009
Literature data are reviewed relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of new multisource and reformulated immediate release (IR) solid oral dosage forms containing quinidine sulfate. Quinidine sulfate's solubility and permeability, its therapeutic use and index, pharmacokinetics, excipient interactions and reported BE/bioavailability (BA) problems were taken into consideration. The available data are not fully conclusive, but do suggest that quinidine sulfate is highly soluble and moderately to highly permeable and would likely be assigned to BCS Class I (or at worst BCS III). In view of the inconclusiveness of the data and, more imp…
The modulation transfer function and signal-to-noise ratio of different digital filters: a technical approach.
2011
The aim of this study was to illustrate the influence of digital filters on the signal-to-noise ratio (SNR) and modulation transfer function (MTF) of digital images. The article will address image pre-processing that may be beneficial for the production of clinically useful digital radiographs with lower radiation dose.Three filters, an arithmetic mean filter, a median filter and a Gaussian filter (standard deviation (SD) = 0.4), with kernel sizes of 3 × 3 pixels and 5 × 5 pixels were tested. Synthetic images with exactly increasing amounts of Gaussian noise were created to gather linear regression of SNR before and after application of digital filters. Artificial stripe patterns with defin…
Numerical expressions for the computation of coincidence-summing correction factors in γ-ray spectrometry with HPGe detectors
2009
Numerical expressions to compute gamma-gamma and gamma-X(K) coincidence summing corrections were deduced by using a suitable computer program and a matrix representation of a decay scheme. For point sources only full-energy peak and total efficiencies are needed. Alternatively, values of peak-to-total ratio can be introduced. For extended sources, the same expressions can be considered with the introduction of "effective efficiencies". Examples of the use of the expressions for point sources and a particulate filter sample measured with a 60% relative efficiency HPGe detector are reported.
Ten years of measured UV Index from the Spanish UVB Radiometric Network.
2013
An analysis is made of the UV Index (UVI) obtained from the ultraviolet erythemal solar radiation (UVER) data measured by the Spanish UVB Radiometric Network between the years 2000 and 2009. Previously, the daily UVI has been evaluated using two different criteria: (a) the value corresponding to solar noon; and (b) the daily maximum value. The mean percentage of agreement is 92% if we consider the cases for which the difference is zero or one UVI unit. These results are similar to those obtained in a previous work where only 2 years were analyzed. In all the stations the UVI reaches very high values (8-10) in spring-summer, and the very high and extreme (≥ 11) UVI values are more dependent …