Search results for "SALIVARY"

showing 10 items of 275 documents

Myoepithelial cells are the main component in pleomorphic adenomas?

2007

Objective: The aim of this study was to quantify by immunohistochemistry the number of myoepithelial cells (MyECs) in pleomorphic adenomas (PAs). Material and methods: We retrieved the paraffin cubes of 27 PAs, new slides were done and they were stained with anti-S100 protein antibody. The amount of S-100 protein positive cells was quantified, their morphology was recorded and comparison among MyEC number with age, gender and involved gland were also done. Results: With S-100 protein, MyECs in normal salivary gland tissue were seen surrounding the ductual structures only. In the analysed PAs a mean of 27.4% of the neoplastic cells were positive to the antibody. With the exception of one PA,…

Adenoma pleomorfoUNESCO::CIENCIAS MÉDICASsalivary gland tumorscélulas mioepitelialestumores de glándulas salivales:CIENCIAS MÉDICAS [UNESCO]proteína S-100Pleomorphic adenomasmyoepithelial cellsS-100 protein
researchProduct

Expression of glial filament protein (GFP) in nerve sheaths and non-neural cells re-examined using monoclonal antibodies, with special emphasis on th…

1986

We describe two novel monoclonal antibodies specific for glial filament protein (GFP), i.e., GF12.23 and GF12.24 (both IgG2a]. These cross-react over a broad range of species with epitopes located in the alpha-helical rod domain typical of all intermediate filament (IF) proteins. These monoclonal antibodies were used, in conjunction with other monoclonal GFP antibodies, rabbit antiserum to GFP, and various antibodies to other cytoskeletal proteins, to examine the occurrence of GFP in cells outside of the central nervous system of rodents, cows, and humans. We detected some scattered GFP-containing cells in the neural sheaths in some species but not in others, and we obtained different resul…

AdenomaCancer Researchmedicine.drug_classGuinea PigsAdenoma PleomorphicFluorescent Antibody TechniqueCross ReactionsMonoclonal antibodyEyeEpitopeEpitheliumSalivary GlandsGreen fluorescent proteinEpitopesSpecies SpecificityGlial Fibrillary Acidic ProteinmedicineAnimalsHumansVimentinIntermediate filamentMolecular BiologyMyelin SheathbiologyMyoepithelial cellAntibodies MonoclonalCell BiologyMolecular biologyRatsMicroscopy FluorescenceMonoclonalImmunologybiology.proteinHepatic stellate cellKeratinsCattleAntibodyDevelopmental BiologyDifferentiation; research in biological diversity
researchProduct

Maternal Microbiota, Cortisol Concentration, and Post-Partum Weight Recovery Are Dependent on Mode of Delivery

2020

© 2020 by the authors.

Adult0301 basic medicineHydrocortisonemicrobiomePhysiologylcsh:TX341-641cortisolBiologydigestive systemArticlecortisol delivery mode microbiome post-partum weight retentionBody Mass Indexdelivery modeFeces03 medical and health sciencesfluids and secretions0302 clinical medicinePregnancyHumansMicrobiomeSalivaSalivary cortisolPost partum2. Zero hunger030219 obstetrics & reproductive medicineNutrition and DieteticsBacteriaCesarean Sectionpost-partum weight retentionVaginal deliveryBody WeightPostpartum Periodfood and beveragesDelivery ObstetricDelivery modeGastrointestinal Microbiome3. Good healthstomatognathic diseases030104 developmental biologyMode of delivery16s rrna gene sequencingFemalelcsh:Nutrition. Foods and food supplyFood ScienceHormoneNutrients
researchProduct

Salivary composition in obese vs normal-weight subjects: towards a role in postprandial lipid metabolism?

2015

In the pathophysiological context of obesity, oral exposure to dietary fat can modulate lipid digestion and absorption but underlying in-mouth mechanisms have not been clearly identified. Therefore we tested the hypothesis that salivary components related to dietary fat sensitivity would differ according to BMI and postprandial lipid metabolism in young men. Saliva was collected from 9 normal-weight (BMI=22.3±0.5 kg/m2) and 9 non-morbid obese (BMI=31.7±0.3 kg/m2) men before a 8 h-postprandial metabolic exploration test involving the consumption of a 40 g fat-meal, in which obese subjects revealed a delayed postprandial lipid metabolism. Nine salivary characteristics (flow, protein content, …

AdultBlood GlucoseMaleSalivamedicine.medical_specialtyproteolysis030309 nutrition & dieteticsEndocrinology Diabetes and Metabolism[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionMedicine (miscellaneous)Context (language use)salivary compositionBody Mass Index03 medical and health sciencesThinnessInternal medicinelipid metabolismmedicineLipolysisHumansObesitySalivaMeals030304 developmental biology0303 health sciencesNutrition and Dieteticsobesebusiness.industryLipid metabolism[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismPostprandial PeriodDietary Fats3. Good healthPostprandialEndocrinologylipolysismedicine.symptombusinessEnergy MetabolismWeight gainBody mass indexLipid digestion[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
researchProduct

Determination of salivary glucose in healthy adults

2009

Podeu consultar la versió en castellà a: http://hdl.handle.net/2445/54584

AdultBlood GlucoseMalemedicine.medical_specialtySalivaDiagnòsticInternal medicineDiagnosismedicineHumansWhole salivaSalivaGeneral Dentistrybusiness.industrySignificant difference:CIENCIAS MÉDICAS [UNESCO]Spearman Correlation TestEndocrinologySalivary glucoseGlucoseOtorhinolaryngologyHealthy individualsGlucosaUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
researchProduct

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease a…

2017

Background Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation. In the current study, we aimed to investigate the possible pathogenic implication of autophagy in T lymphocytes in patients with pSS. Methods Thirty consecutive pSS patients were recruited together with 20 patients affected by sicca syndrome and/or chronic sialoadenitis and 30 healthy controls. Disease activity and damage were evaluated according to SS disease activity index, EULAR SS disease activity index, and SS disease damage index. T lymphocytes were analyzed for the expression of autophagy-specific marke…

AdultCD4-Positive T-LymphocytesMale0301 basic medicinePathologymedicine.medical_specialtylcsh:Diseases of the musculoskeletal systemAutophagy; Cytokines; Lymphocytes; Sjögren syndrome; Immunology and Allergy; Rheumatology; ImmunologyLymphocyteImmunologySjögren syndromeSalivary GlandsPathogenesis03 medical and health sciencesImmune systemRheumatologystomatognathic systemSicca syndromeAutophagymedicineImmunology and AllergyHumansLymphocytesCytokineAgedSjögren syndrome; Autophagy; Lymphocytes; CytokinesAutoimmune diseaseSalivary glandbusiness.industryAutophagyT lymphocyteMiddle Agedmedicine.diseaseSjögren syndromeUp-RegulationSettore MED/16 - Reumatologiastomatognathic diseasesSjogren's Syndrome030104 developmental biologymedicine.anatomical_structureImmunologyCytokinesLymphocyteFemalelcsh:RC925-935businessResearch ArticleArthritis Research & Therapy
researchProduct

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

2012

OBJECTIVES: In chronic inflammatory disorders, interleukin (IL)-22 may act either as a protective or as a pro-inflammatory cytokine. At mucosal sites, IL-22 is mainly produced by CD4(+) T cells and by a subset of mucosal natural killer (NK) cells expressing the receptor NKp44 (NKp44(+) NK cells). The aim of this study was to investigate the IL-22 expression in the salivary glands of patients with primary Sjögren's syndrome (pSS). METHODS: Minor salivary gland biopsies were obtained from 19 patients with pSS and 16 with non-specific chronic sialoadenitis. Quantitative gene expression analysis by TaqMan real-time PCR and immunohistochemistry for IL-17, IL-22, IL-23 and STAT3 (signal transduce…

AdultCD4-Positive T-LymphocytesMaleSTAT3 Transcription FactorAnkylosing Spondylitis IL-22 NKp44NK cells intestinal inflammationmedicine.medical_treatmentImmunologySalivary Glands MinorInterleukin-23General Biochemistry Genetics and Molecular BiologySialadenitisInterleukin 22PathogenesisRheumatologyintestinal inflammationIL-22Immunology and AllergyMedicineHumansRNA MessengerSTAT3ReceptorAgedAnkylosing SpondylitibiologySalivary glandNatural Cytotoxicity Triggering Receptor 2business.industryReverse Transcriptase Polymerase Chain ReactionInterleukinsInterleukin-17InterleukinMiddle AgedNKp44NK cellKiller Cells NaturalSettore MED/16 - ReumatologiaCytokinemedicine.anatomical_structureSjogren's SyndromeCase-Control StudiesImmunologybiology.proteinImmunohistochemistryFemalebusinessAnnals of the rheumatic diseases
researchProduct

Immunohistochemical expression of p21 in normal tissues of salivary gland, pleomorphic adenoma and carcinoma ex pleomorphic adenoma (undifferentiated…

2009

Objective: Our study aimed to characterize alteration in the immunohistochemical expression of p21 in normal tissue of the salivary gland surrounding pleomorphic adenoma, the tumor cells of pleomorphic adenomas, and carcinoma arising in pleomorphic adenoma. Study design: A selected series of 29 cases of pleomorphic adenomas, and 27 cases of carcinoma ex-pleomorphic adenoma (undifferentiated and adenocarcinoma types) were examined. Results: The results showed that p21 expression was negative in the most components of normal tissue of the salivary gland surrounding pleomorphic adenoma, 24 cases out of 29 of the non tumour duct cells (82.8%), and 28 (96.6%) cases out of 29 of the acinar cells …

AdultCyclin-Dependent Kinase Inhibitor p21MalePathologymedicine.medical_specialtyAdenomaAdenoma PleomorphicAdenocarcinomaSalivary GlandsPleomorphic adenomaYoung AdultmedicineCarcinomaHumansGeneral DentistryAgedAged 80 and overSalivary glandbusiness.industrySalivary Gland Pleomorphic AdenomaMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseSalivary Gland NeoplasmsImmunohistochemistrydigestive system diseasesCarcinoma ex pleomorphic adenomamedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASAdenocarcinomaImmunohistochemistrySurgeryFemalebusiness
researchProduct

Salivary testosterone is related to both handedness and degree of linguistic lateralization in normal women.

2003

The aim of this study was to test the hypothesis that individual differences in testosterone (T) are associated with different patterns of linguistic lateralization and hand preference. Twenty left-handed (LH) and 19 right-handed (RH) women filled in a handedness questionnaire and performed a consonant–vowel dichotic listening test (DL-CV). Salivary T was measured by radioimmunoassay (RIA). LH women showed significantly lower mean salivary T than RH women. T levels were negatively correlated with the absolute value of the DL laterality index. Subjects with right ear advantage (REA) were classified into strongly and weakly lateralized following Wexler et al. method (Brain Lang. 13 (1981) 13)…

AdultHydrocortisonemedicine.drug_classEndocrinology Diabetes and MetabolismStatistics as TopicLateralization of brain functionFunctional LateralityDichotic Listening TestsEndocrinologyReference ValuesProhibitinsmedicineHumansTestosteroneSalivaBiological PsychiatryTestosteroneLanguageSex CharacteristicsEndocrine and Autonomic SystemsDichotic listeningSalivary testosteroneCognitionAndrogenDegree (music)LinguisticsPsychiatry and Mental healthLateralityFemalePsychologyPsychoneuroendocrinology
researchProduct

Changes in different salivary biomarkers related to physiologic stress in elite handball players: the case of females

2019

AbstractThis study evaluates pre- and post-match concentrations of salivary cortisol, alpha-amylase (AA) and immunoglobulin A (lgA) in a group of 21 elite female handball players in the Spanish national women’s league. The players’ mean age was 23.0 ± 5.4 years. The concentration of the biomarkers was determined using ELISA. Mean playing time was 25.2 min. The players’ cortisol concentration increased significantly (p < 0.05) whereas the IgA concentration fell significantly (p < 0.01) at the end of the match. There were no significant changes in the concentrations of AA between pre and post-match timepoints. The changes observed in the study also depended on the position played; defen…

AdultImmunoglobulin AAdolescentHydrocortisonelcsh:MedicineAdrenergicPhysiologyAthletic PerformanceArticleYoung Adult03 medical and health sciencesApplied immunology0302 clinical medicineStress PhysiologicalHumansMedicinelcsh:ScienceSalivaSalivary biomarkersSalivary cortisolMultidisciplinarybiologybusiness.industrylcsh:RDiagnostic markersMean age030229 sport sciencesImmunoglobulin Abiology.proteinlcsh:QFemalealpha-AmylasesImmunocompetencebusinessBiomarkers030217 neurology & neurosurgeryScientific Reports
researchProduct