Search results for "SAMPLE"
showing 10 items of 2270 documents
Bayesian analysis and design for comparison of effect-sizes
2002
Comparison of effect-sizes, or more generally, of non-centrality parameters of non-central t distributions, is a common problem, especially in meta-analysis. The usual simplifying assumptions of either identical or non-related effect-sizes are often too restrictive to be appropriate. In this paper, the effect-sizes are modeled as random effects with t distributions. Bayesian hierarchical models are used both to design and analyze experiments. The main goal is to compare effect-sizes. Sample sizes are chosen so as to make accurate inferences about the difference of effect-sizes and also to convincingly solve the testing of equality of effect-sizes if such is the goal.
A Monte Carlo study comparing PIV, ULS and DWLS in the estimation of dichotomous confirmatory factor analysis
2012
We conducted a Monte Carlo study to investigate the performance of the polychoric instrumental variable estimator (PIV) in comparison to unweighted least squares (ULS) and diagonally weighted least squares (DWLS) in the estimation of a confirmatory factor analysis model with dichotomous indicators. The simulation involved 144 conditions (1,000 replications per condition) that were defined by a combination of (a) two types of latent factor models, (b) four sample sizes (100, 250, 500, 1,000), (c) three factor loadings (low, moderate, strong), (d) three levels of non-normality (normal, moderately, and extremely non-normal), and (e) whether the factor model was correctly specified or misspecif…
Multiple testing in candidate gene situations: a comparison of classical, discrete, and resampling-based procedures.
2011
In candidate gene association studies, usually several elementary hypotheses are tested simultaneously using one particular set of data. The data normally consist of partly correlated SNP information. Every SNP can be tested for association with the disease, e.g., using the Cochran-Armitage test for trend. To account for the multiplicity of the test situation, different types of multiple testing procedures have been proposed. The question arises whether procedures taking into account the discreteness of the situation show a benefit especially in case of correlated data. We empirically evaluate several different multiple testing procedures via simulation studies using simulated correlated SN…
Power of the Wilcoxon–Mann–Whitney test for non‐inferiority in the presence of death‐censored observations
2017
In clinical trials with patients in a critical state, death may preclude measurement of a quantitative endpoint of interest, and even early measurements, for example for intention-to-treat analysis, may not be available. For example, a non-negligible proportion of patients with acute pulmonary embolism will die before 30 day measurements on the efficacy of thrombolysis can be obtained. As excluding such patients may introduce bias, alternative analyses, and corresponding means for sample size calculation are needed. We specifically consider power analysis in a randomized clinical trial setting in which the goal is to demonstrate noninferiority of a new treatment as compared to a reference t…
Sample size planning for survival prediction with focus on high-dimensional data
2011
Sample size planning should reflect the primary objective of a trial. If the primary objective is prediction, the sample size determination should focus on prediction accuracy instead of power. We present formulas for the determination of training set sample size for survival prediction. Sample size is chosen to control the difference between optimal and expected prediction error. Prediction is carried out by Cox proportional hazards models. The general approach considers censoring as well as low-dimensional and high-dimensional explanatory variables. For dimension reduction in the high-dimensional setting, a variable selection step is inserted. If not all informative variables are included…
A GALTON-WATSON BRANCHING PROCESS IN VARYING ENVIRONMENTS WITH ESSENTIALLY CONSTANT OFFSPRING MEANS AND TWO RATES OF GROWTH1
1983
Summary A Galton-Watson process in varying environments (Zn), with essentially constant offspring means, i.e. E(Zn)/mnα∈(0, ∞), and exactly two rates of growth is constructed. The underlying sample space Ω can be decomposed into parts A and B such that (Zn)n grows like 2non A and like mnon B (m > 4).
Quick counts from non-selected polling stations
2008
Countless examples of misleading forecasts on behalf of both campaign and exit polls affecting, among others, British, French, and Spanish elections could be found. This has seriously damaged their image. Therefore, procedures should be used that minimize errors, especially on election night when errors are more noticeable, in order to maintain people's trust in surveys. This paper proposes a method to obtain quick and early outcome forecasts on the election night. The idea is to partly sample some (whatever) polling stations and use the consistency that polling stations show between elections to predict the final results. Model accuracy is analysed through simulation using seven different …
Regional Inequalities in Consumption Patterns: A Multilevel Approach to the Case of Italy
2007
Summary The main aim of this paper is to evaluate the disparities in the Italian regions on the demand side. In more detail, an attempt will be made to find if the consumption behaviour of Italian households is different in the regions. With this in mind, Istat's 2000 Italian Family Budget data set was analysed. The data in question, which were collected through a two-stage sample over Italy's 20 regions, contains information regarding the expenses of approximately 23,000 households. In this analysis, both households and regions are considered as units: households are nested in the regions so that the basic data structure is hierarchical. In order to take this hierarchical structure into ac…
Catecholamine Response Curves of Male Hypertensives Identified by Lehmacher's Two Sample Configural Frequency Analysis
1997
A new application of LEHMACHER'S (1980) marginal homogeneity sign tests is given by analysis of bivariate response curves (or response surfaces) in two unpaired samples of hypertensive versus normotensive patients. Rationale and computations are illustrated by empirical data from sympathomedullary stress research.
Sequentially Rejective Test Procedures for Detecting Outlying Cells in One- and Two-Sample Multinomial Experiments
1985
For multiple testing of multinomial models in the case of one or two samples we propose using test procedures based on the principle described by MARCUS, PERITZ and GABRIEL (1976). These methods are based in each step of the sequentially rejective strategy on tests which exhaust the full α level (i.e. which are not conservative). The tests can be performed in a finite or asymptotic version.