Search results for "SART"
showing 10 items of 212 documents
Angiotensin Receptor Neprilysin Inhibition Compared With Enalapril on the Risk of Clinical Progression in Surviving Patients With Heart Failure
2015
Background— Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known about the effect of drugs on the risk of clinical deterioration in surviving patients. Methods and Results— We compared the angiotensin-neprilysin inhibitor LCZ696 (400 mg daily) with the angiotensin-converting enzyme inhibitor enalapril (20 mg daily) in 8399 patients with heart failure and reduced ejection fraction in a double-blind trial. The analyses focused on prespecified measures of nonfatal clinical deterioration. In comparison with the enalapril group, fewer LCZ696-treated patients required intensification of med…
Mity antyczne we francuskim dramacie XX wieku (na wybranych przykładach)
2017
The French theatre of the 20th century willingly treats and revisits ancient myths. Oedipus, Antigone, Electra, the Trojan War, Amphitryon appear in many writers’ works. The myth of Electra in Jean Giraudouxs version entitled Electra (1937), as well as Jean-Paul Sartres The Flies (1942) are interesting examples of metatexts. Face to the threat of war, Giraudoux, who was a diplomat and a Germanophile, focuses on the problem of power, responsibility, and justice, while Sartre exemplifies the existentialist philosophy and its main element: a man who is responsible for his actions and condemned to freedom. This was a particular challenge during the period of war and occupation. Jean Anouilh, in…
Aspetto e Azione nel verbo gotico
2006
The Cercle de l’Ermitage by Alberto Sartoris. Axonometry as a Synthetic Representation of the Project
2022
Analisi della cromolitografia di Alberto Sartoris pubblicata nel 1936 dalla rivista The Architectural Review. Analysis of Alberto Sartoris' chromolithography published in 1936 in The Architectural Review.
Los espacios públicos de la cotidianeidad / 3
2006
Los espacios públicos de la cotidianeidad / 4
2006
La relation Beauvoir-Sartre ou le dialogue existentiel et intellectuel maître(sse)-disciple
2019
The legendary relation between Simone de Beauvoir and Jean-Paul Sartre was based on a specific communion of the two existentialists ’ souls and bodies. It is Sartre that is generally considered to be the spiritual guide of this duo and that is why his role should be approached with caution in order to show that Beauvoir was by no means an epigone of her master. A contrario, it is the inspiration stemming from her literary output that can be found in a handful of works authored by the founder of Les Temps modernes (Modern Times). This impact is particularly conspicuous in the play entitled Dirty Hands, referring to The Second Sex, in which the author reflects on the concept of myth and shows…
AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats.
2008
Several enzymatic sources of reactive oxygen species (ROS) were described as potential reasons of eNOS uncoupling in diabetes mellitus. In the present study, we investigated the effects of AT1-receptor blockade with chronic telmisartan (25 mg/kg/day, 6.5 weeks) therapy on expression of the BH4-synthesizing enzyme GTP-cyclohydrolase I (GCH-I), eNOS uncoupling, and endothelial dysfunction in streptozotocin (STZ, 60 mg/kg iv, 7 weeks)-induced diabetes mellitus (type I). Telmisartan therapy did not modify blood glucose and body weight. Aortas from diabetic animals had vascular dysfunction as revealed by isometric tension studies (acetylcholine and nitroglycerin potency). Vascular and cardiac RO…
Losartan reduces microalbuminuria in hypertensive microalbuminuric type 2 diabetics.
2001
Background. The aim of the present study was to assess the antialbuminuric effect of losartan in a large number of hypertensive type 2 diabetics. Methods. This was a 6-month, open-label, prospective and multicentre study. A total of 422 patients with type 2 diabetes who were hypertensive [sitting systolic blood pressure (SBP) > 140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg] and microalbuminuric [urinary albumin excretion (UAE) 30-300 mg/day] were eligible for the study. After a 2-week run-in period, patients were placed on losartan 50 mg once a day. If the BP did not reach the desired goal (<140/90 mmHg) after a 4-week period, the losartan dose was doubled. In the absence of contr…
METAMORPHIC EVOLUTION OF SPESSARTINE QUARTZITES (COTICULES) IN THE HIGH-PRESSURE, LOW-TEMPERATURE COMPLEX AT BAHIA MANSA, COASTAL CORDILLERA OF SOUTH…
2001
Lenses of spessartine quartzites (coticules) are associated with greenschist intercalations in coastal exposures at Bahia Mansa within the mainly metapsammopelitic Western Series, which forms most of the basement in the Coastal Cordillera of central to southern Chile. The chemical compositions of the coticules can be explained by protoliths formed from ferriferous and manganiferous hydrothermal precipitates mixed with aluminous alteration-derived material on top of oceanic crust. The peak conditions of metamorphism were calculated with multivariant reactions: 270–370 °C, 6–8 kbar. A retrograde P–T evolution was marked by decompression to 2 kbar during cooling below 300°C, influx of an exter…