Search results for "SBI"
showing 10 items of 258 documents
IBD, malignancy and oral microbiota: Analysis of the literature
2016
The human microbiota, in adults, varies in number and species based on the location in the gastrointestinal tract. The highest concentration is at the intestinal level, where mainly Bacteroidetes, Actinobacteria, Firmicutes and proteobacteria are found. Instead, in the oral cavity, five major phyla exists. Firmicutes, Actinobacteria, Proteobacteria, Bacteroidetes and Fusobacteria. Variations in the microbiota cause bysbiosis, which is responsible to a great extent for the onset of many diseases including inflammatory bowel disease (IBD) and colorectal cancer (CRC). In some cases (8-10%) IBD has shown oral manifestations that may reflect a change in the composition of the oral microbiota. Th…
The influence of some dietary components on intestinal microbiota
2016
The gut microbiota is the set of symbiotic microorganisms that resides in our intestine. The interaction between the gut microbiota and the mucosal immune system can be altered as a result of shifts in the composition or metabolic activity of the intestinal microflora. Recent studies establish that diet is one of the main involved factors in determining the microbial composition of the gut suggesting its role as external factor able to promote the onset of specific diseases by disrupting the immune homeostasis. Starting from the evidence that the 57% of the gut microbiota’s entire variation are due to dietary alterations this review aims at providing an overview of the positive impact of so…
The intestinal ecosystem and probiotics
2016
The term "probiotic" comes from the greek "pro bios" and means "pro life": Nowadays, an increasing number of pharmaceutical preparations and functional foods are enriched with probiotics and for the patients it is increasingly important to receive information needed to know how to orient in the choice. The benefits from probiotics are many and include the modulation of the intestinal microflora (stimulation of beneficial bacteria and inhibition of pathogens), the support of bowel function and the stimulation of the immune system. This broad spectrum of beneficial effects to maintain efficient the intestinal ecosystem. Therefore, probiotics are an useful tool to prevent the formation of diso…
Senās DNS analīžu pielietojums Latvijas teritorijas dzelzs laikmeta apbedījumu raksturojumā
2022
Darba mērķis: analizēt Latvijas teritorijā iegūto arheoloģisko osteoloģisko materiālu, veicot senās DNS analīzi, lai novērtētu endogēnās DNS saglabātības pakāpi un paplašinātu esošās zināšanas par Daugavas un Mēmeles krastus apdzīvojušo iedzīvotāju ģenētisko izcelsmi. Tika veikta mtDNS haplogrupu sastopamības izpēte senās DNS paraugiem, gan izmantojot publicētus rezultātus, gan veicot senās DNS analīzi dzelzs laikmeta paraugiem. Dzelzs laikmetā Latvijas teritorijā konstatējamas jaunas mtDNS haplogrupas, kas sakrīt ar līdzīgi datētām arī citur Baltijas jūras reģionā. Pētījumā izmantotās metodes ir efektīvas, tomēr nelielais mtDNS haplogrupu rezultātu skaits var tikt saistīts ar zemu senās DN…
Simulēta un presbiopijas radīta apmiglojuma ietekme uz tuvuma darbu veiktspēju
2019
Maģistra darbs ir uzrakstīts latviešu valodā uz 44 lapām. Tas satur 19 attēlus, 5 tabulas un 69 atsauces uz literatūras avotiem. Darba mērķis: novērtēt, kā mainās tuvuma darbu veiktspēja presbiopijas un simulētās presbiopijas grupas dalībniekiem pie dažādām apmiglojuma vērtībām. Dalībnieki: eksperimentā piedalījās 81 dalībnieks, 9 simulētās presbiopijas grupas dalībnieki (vidējais vecums 22 ± 2 gadi), 72 presbiopijas grupas dalībnieki (vidējais vecums 51 ± 3 gadi). Metode: tika veikts meklēšanas un lasīšanas uzdevums bez apmiglojuma un pie dažādiem apmiglojuma lielumiem. Rezultāti un secinājumi: lasīšanas ātrums nozīmīgi mainās visu grupu ietvaros pie 1,00 D apmiglojuma, toties meklēšanas u…
Running against time: conservation of the remaining hawksbill turtle (Eretmochelys imbricata) nesting population in the Dominican Republic
2012
Saona Island hosts the last hawksbill turtle (Eretmochelys imbricata) nesting population in the Dominican Republic, which has experienced a severe decline in the last decades, mostly due to illegal egg take. Here we present the results of an artificial incubation programme started in 2007 to protect the clutches from human predation. A preliminary survey in 2006 showed that about 60% of clutches laid were taken by humans. Over the study period (2007–2010) we recorded 400 clutches, of which 38.2% were predated by humans, 40.7% were artificially incubated and 21% were incubated in situ. Overall, the artificial incubation programme allowed the release of 12,340 hatchlings. No differences were …
Context dependent variation in corticosterone and phenotypic divergence of Rana arvalis populations along an acidification gradient
2022
Background Physiological processes, as immediate responses to the environment, are important mechanisms of phenotypic plasticity and can influence evolution at ecological time scales. In stressful environments, physiological stress responses of individuals are initiated and integrated via the release of hormones, such as corticosterone (CORT). In vertebrates, CORT influences energy metabolism and resource allocation to multiple fitness traits (e.g. growth and morphology) and can be an important mediator of rapid adaptation to environmental stress, such as acidification. The moor frog, Rana arvalis, shows adaptive divergence in larval life-histories and predator defense traits along an acidi…
Applying the Anna Karenina principle for wild animal gut microbiota : temporal stability of the bank vole gut microbiota in a disturbed environment
2020
Gut microbiota play an important role in host health. Yet, the drivers and patterns of microbiota imbalance (dysbiosis) in wild animals remain largely unexplored. One hypothesised outcome of stress on animal microbiomes is a destabilised microbial community that is characterised by an increase in inter-individual differences compared with microbiomes of healthy animals, which are expected to be (i) temporally stable and (ii) relatively similar among individuals. This set of predictions for response of microbiomes to stressors is known as the Anna Karenina principle (AKP) for animal microbiomes. We examine the AKP in a wild mammal inhabiting disturbed environments by conducting a capture-mar…
From Dysbiosis to Neurodegenerative Diseases through Different Communication Pathways: An Overview
2023
The microbiome research field has rapidly evolved over the last few decades, becoming a major topic of scientific and public interest. The gut microbiota (GM) is the microbial population living in the gut. The GM has many functions, such as maintaining gut homeostasis and host health, providing defense against enteric pathogens, and involvement in immune system development. Several studies have shown that GM is implicated in dysbiosis and is presumed to contribute to neurodegeneration. This review focuses mainly on describing the connection between the intestinal microbiome alterations (dysbiosis) and the onset of neurodegenerative diseases to explore the mechanisms that link the GM to nerv…
Vesiclepedia:A Compendium for Extracellular Vesicles with Continuous Community Annotation
2012
Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles.