Search results for "SBRT"

showing 3 items of 3 documents

Hypo-fractionated stereotactic radiation therapy for lung malignancies by means of helical tomotherapy: report of feasibility by a single-center expe…

2018

Background: Several experiences in the literature report SBRT as an effective treatment option for medically inoperable early stage non-small cell lung cancer (NSCLC) and oligometastatic disease. The optimal fractionation schedules and total dose remain controversial. In this study, we evaluated the safety in terms of toxicity and efficacy of using of 8–10 fractions schedules with Helical Tomotherapy (HT) for primary and metastatic lung lesions. Methods: Between March 2014 and May 2016, a total of 39 patients (median age 72 years, range 26–91) were treated with HT-SBRT for malignant lung lesions: 22 patients with early stage NSCLC, 17 with oligometastases. Patients received 8–10 fract…

AdultMalemedicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentStereotactic radiation therapyRadiosurgerySingle CenterTomotherapy030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineHelical tomotherapyCarcinoma Non-Small-Cell LungmedicineHumansRadiology Nuclear Medicine and imagingStage (cooking)Lung cancerAgedPneumonitisAged 80 and overSBRTHelical tomotherapy; Lung cancer; Radiotherapy; SBRTRadiotherapybusiness.industryRadiotherapy DosageGeneral MedicineMiddle Agedmedicine.diseaseSurvival RateRadiation therapyTreatment Outcome030220 oncology & carcinogenesisFeasibility StudiesFemaleDose Fractionation RadiationRadiologyLung cancerbusinessTomography Spiral ComputedEsophagitis
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Stereotactic Radiotherapy in Early-Stage Breast Cancer in Neoadjuvant and Exclusive Settings: A Systematic Review

2022

<b><i>Introduction:</i></b> Breast cancer (BC) is one of the most common tumors; better screening policies and multidisciplinary approach allow personalized treatment. Radiotherapy (RT) plays a central role in the multimodal approach in BC, and recent evidence has shown the non-inferiority of hypofractionated treatments. The aim of this study was to describe the feasibility and validity of stereotactic RT (SBRT) in BC in a neoadjuvant and exclusive setting. <b><i>Methods:</i></b> A PubMed/MEDLINE and Embase systematic review was conducted to assess the role of radiomics in BC. The search strategy was “breast [All Fields] AND “stereotactic” [Al…

Cancer ResearchBreast cancerSBRTOncologyRadiotherapySettore MED/06 - Oncologia MedicaHematology
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Spinal metastases: Is stereotactic body radiation therapy supported by evidences?

2016

Stereotactic body radiotherapy (SBRT) is becoming widely adopted in the treatment of primary and secondary tumors. Spinal bone metastases are frequently discovered in cancer patients, and in the past have been usually treated with a palliative goal. Nevertheless, in some particular clinical settings, such as oligometastatic patients and/or those with a long life expectancy, spinal SBRT could be considered a valid therapeutic option to obtain long-lasting palliation and, when possible, with a curative goal. This review aims to summarize available clinical and dosimetric data of published studies about spinal SBRT.

medicine.medical_specialtyPalliative careStereotactic body radiation therapymedicine.medical_treatment2720 HematologyBone Neoplasms610 Medicine & healthClinical settingsRadiosurgeryRadiosurgery030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineDosimetryFractures CompressionPalliative radiotherapymedicineHumansSBRTSpinal NeoplasmsToxicitySpine metastasesbusiness.industryPalliative CareCompressionCancerRadiotherapy DosageHematologymedicine.disease10044 Clinic for Radiation OncologySurgeryTreatment OutcomeOncologyLocal controlDosimetry; Local control; Palliative radiotherapy; SBRT; Spine metastases; Toxicity; Bone Neoplasms; Evidence-Based Practice; Fractures Compression; Humans; Palliative Care; Radiotherapy Dosage; Spinal Fractures; Spinal Neoplasms; Treatment Outcome; Radiosurgery; Hematology; Oncology; Geriatrics and GerontologyEvidence-Based Practice030220 oncology & carcinogenesisSpinal Fractures2730 OncologySecondary tumorsGeriatrics and GerontologySpinal metastasesbusinessFracturesStereotactic body radiotherapyCritical Reviews in Oncology/Hematology
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