Search results for "SCA"

showing 10 items of 23299 documents

Pharmacotherapy of female urinary incontinence

2005

Urinary incontinence is a major clinical problem and a significant cause of disability and dependency in older adults. Overall, the prevalence of urinary incontinence approaches 55% among women aged over 55 years. The past few years have seen significant advances in the pharmacotherapy of overactive bladder and stress incontinence. The review examines the evidence regarding their benefits and side-effects.

medicine.medical_specialtyStress incontinencebusiness.industryHealth StatusUrinary Incontinence StressAnti-Infective Agents UrinaryUrologyObstetrics and GynecologyEstrogensUrinary incontinenceMuscarinic AntagonistsMiddle Agedmedicine.diseaseAdrenergic AgonistsCholinergic AntagonistsPharmacotherapyOveractive bladderInternal medicineQuality of LifeHumansWomen's HealthMedicineFemalemedicine.symptombusinessBritish Menopause Society Journal
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A regenerative 3D scaffold for inguinal hernia repair. MR imaging and histological cross evidence. Qualitative study

2021

Abstract Background Inguinal hernia is a degenerative disease occurring in a high motile surround. Stopping degeneration and promoting tissue regeneration should be the treatment goal. Groin hernias are conventionally managed with static flat meshes, mostly fixated to the delicate inguinal environment. Far from a regenerative effect, the biologic response of conventional hernia meshes is characterized by a foreign body reaction leading to a stiff/shrunken scar plate, which is often the source of unpleasant complications. Recently, a newly engineered 3D device for inguinal hernia repair – ProFlor-has been developed to produce a regenerative biological response. Unlike conventional hernia mes…

medicine.medical_specialtySwineAdipose tissueHernia InguinalGroinProsthesesDegenerative diseaseMagnetic resonance imagingmedicineAnimalsHerniaHerniorrhaphymedicine.diagnostic_testGroinbusiness.industryInguinal herniaMagnetic resonance imagingHistologyGeneral MedicineSurgical Meshmedicine.diseaseInguinal herniamedicine.anatomical_structureHernia genesisPorcine experimental modelSurgeryRadiologyForeign bodybusinessRegenerative scaffolds
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The influence of the C1-inhibitor BERINERT® and the protein-free haemodialysate ACTIHAEMYL20%® on the evolution of the depth of scald burns in a porc…

1997

Standardized deep partial-thickness burns were inflicted on domestic pigs by scalding 30 per cent of the skin surface for 25 s with 75 degrees C hot water. The animals (n = 18; weight 25-35 kg) were divided into three groups: I, control group (n = 6), Ringer's lactate only; II, haemodialysate group (n = 6), Ringer's lactate and a protein-free haemodialysate of calf-blood (ACTIHAEMYL20%; AH) and III, C1-inhibitor group (n = 6), Ringer's lactate and C1-inhibitor (C1-INH; BERINERT). Skin biopsies were taken at defined time points (4, 28, 52 and 76 h) and investigated histologically. Depth of burn was determined morphometrically after coloration with a modified MTT-staining on frozen sections o…

medicine.medical_specialtySwineComplement C1 Inactivator ProteinsCritical Care and Intensive Care MedicineStatistics NonparametricMicrocirculationC1-inhibitorRandom AllocationReference ValuesBiopsySkin surfacemedicineScaldingAnimalsSkinWound Healingmedicine.diagnostic_testbiologybusiness.industryBiopsy NeedleHistologyGeneral Medicinemedicine.diseaseSurgeryDisease Models AnimalProtein freeAnesthesiaDisease ProgressionEmergency Medicinebiology.proteinActihaemylSurgeryBurnsWound healingbusinessComplement C1 Inhibitor ProteinBurns
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Modulatory action of acetylcholine on cerebrovascular sympathetic neurotransmission

1991

1. Acetylcholine (10 micrograms/min) diminished the electrically-induced cerebral blood flow reductions. Atropine (1-2 mg) partially blocked this inhibitory effect. 2. Exogenously administered noradrenaline (1-10 micrograms) and tyramine (50-500 micrograms) reduced cerebral blood flow but this effect was unchanged by acetylcholine infusion. 3. Acetylcholine inhibited the nonadrenergic component of the electrically-induced contraction at a concentration greater than or equal to 10(-6) M and potentiated the adrenergic component at a concentration greater than or equal to 10(5) M. Atropine 10(-7) M) inhibited both of these effects. In addition, acetylcholine (10(-4) M) enhanced the electricall…

medicine.medical_specialtySympathetic Nervous SystemContraction (grammar)Cerebral arteriesTyramineAdrenergicTetrodotoxinIn Vitro TechniquesSynaptic TransmissionMuscle Smooth VascularNorepinephrinechemistry.chemical_compoundIsometric ContractionInternal medicineMuscarinic acetylcholine receptormedicineAnimalsPharmacologyChemistryGoatsMuscarinic acetylcholine receptor M3Cerebral ArteriesTyramineAcetylcholineElectric StimulationAtropineEndocrinologyCerebrovascular CirculationFemaleAcetylcholinemedicine.drugGeneral Pharmacology: The Vascular System
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Do adrenergic fibres have muscarinic inhibitory receptors?-- a reply.

1974

medicine.medical_specialtySympathetic Nervous SystemPharmaceutical ScienceAdrenergicIn Vitro TechniquesDogsInternal medicineMuscarinic acetylcholine receptormedicineAnimalsReceptors CholinergicSaphenous VeinPharmacologyNeuronsChemistryInhibitory receptorsHeartAcetylcholineElectric StimulationStimulation ChemicalMesenteric ArteriesRatsPerfusionEndocrinologyCatsRabbitsSpleenThe Journal of pharmacy and pharmacology
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The interferance of muscarinic receptors with the noradrenaline release from sympathetic nerve endings caused by nicotinic agents.

1968

medicine.medical_specialtySympathetic nervous systemSympathetic Nervous SystemReceptors DrugIn Vitro TechniquesPiperazinesNorepinephrineInternal medicineMuscarinic acetylcholine receptorMuscarinic acetylcholine receptor M4medicineAnimalsSympathomimeticsPharmacologyNerve EndingsChemistryMyocardiumMuscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2General MedicineMuscarinic acetylcholine receptor M1AcetylcholinePerfusionEndocrinologymedicine.anatomical_structureRabbitsFree nerve endingAcetylcholinemedicine.drugNaunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie
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Patterns of sympathetic responses induced by different stress tasks.

2008

Stress tasks are used to induce sympathetic nervous system (SNS) arousal. However, the efficacy and the patterns of SNS activation have not been systematically compared between different tasks. Therefore, we analyzed SNS activation during the following stress tasks: Presentation of negative, positive, and – as a control – neutral affective pictures, Color-Word interference test (CWT), mental arithmetic under time limit, singing a song aloud, and giving a spontaneous talk. We examined 11 healthy subjects and recorded the following SNS parameters: Activation of emotional sweating by quantitative sudometry, skin vasoconstriction by laser-Doppler flowmetry, heart rate by ECG, blood pressure by …

medicine.medical_specialtySympathetic nervous systemanimal structuresVisual analogue scaleAudiologyArticleArousalPsychiatry and Mental healthmedicine.anatomical_structureBlood pressureNeurologyStress (linguistics)Heart ratemedicineNeurology (clinical)medicine.symptomPsychologyTrapezius muscleSocial psychologyVasoconstriction
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Multiscale Information Decomposition Dissects Control Mechanisms of Heart Rate Variability at Rest and During Physiological Stress.

2019

Heart rate variability (HRV

medicine.medical_specialtyTechnology and Engineering0206 medical engineeringRR intervalRESPIRATORY SINUS ARRHYTHMIAPERIODGeneral Physics and Astronomysynergylcsh:Astrophysics02 engineering and technologyBiologyBaroreflexArticle03 medical and health sciences0302 clinical medicinestomatognathic systemInternal medicinelcsh:QB460-466RespirationMedicine and Health Sciencesmedicineotorhinolaryngologic diseasesHeart rate variabilitycardiovascular diseasesVagal tonelcsh:SciencePhysiological stressinformation theoryBAROREFLEXredundancyheart rate variabilityvirus diseasesmultiscale analysisEntropy cardiovascular variability redundancy autonomic nervous system020601 biomedical engineeringlcsh:QC1-999ARTERIAL-PRESSUREAutonomic nervous systemBlood pressuretime series analysisCardiologyinformation decompositionlcsh:QentropyCARDIOPULMONARYlcsh:Physics030217 neurology & neurosurgerycirculatory and respiratory physiologyEntropy (Basel, Switzerland)
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Efficiency of telemedicine for acute stroke: a cost-effectiveness analysis from a French pilot study

2020

AbstractObjectivesTelestroke is an effective way to improve care and health outcomes for stroke patients. This study evaluates the cost-effectiveness of a French telestroke network.MethodsA decision analysis model was built using population-based data. We compared short-term clinical outcomes and costs for the management of acute ischemic stroke patients before and after the implementation of a telestroke network from the point of view of the national health insurance system. Three effectiveness endpoints were used: hospital death, death at 3 months, and severe disability 3 months after stroke (assessed with the modified Rankin scale). Most clinical and economic parameters were estimated fr…

medicine.medical_specialtyTelemedicineCost effectivenessCost-Benefit AnalysisPopulationPilot Projects030204 cardiovascular system & hematologyEfficiency OrganizationalState MedicineDisability Evaluation03 medical and health sciences0302 clinical medicineModified Rankin ScaleHumansMedicineHospital MortalityeducationStrokeTelerehabilitationAcute strokeeducation.field_of_studybusiness.industryHealth PolicyStroke RehabilitationCost-effectiveness analysismedicine.diseaseStrokeModels EconomicEmergency medicineFranceHealth Expendituresbusiness030217 neurology & neurosurgeryDecision analysisInternational Journal of Technology Assessment in Health Care
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Static Crow’s Feet Treated with Voltaic Arc Dermabrasion (Atmospheric Plasma): Post-Operative Pain Assessment by Thermal Infrared Imaging

2021

Background: In the literature, several strategies have been described for the treatment of unaesthetic marks on the face resulting from the aging processes. The atmospheric plasma procedure is a non-invasive, inexpensive technique proposed for the rejuvenation of facial tissues. The aim of this study was to evaluate the performance of voltaic arc dermabrasion (VAD) for the treatment of static crow’s feet of the periorbital area. Methods: The crow’s feet of 135 patients (127 female and 8 male) were treated using the VAD technique. The perioperative skin temperature measurement was assessed using an Infrared Temperature sensor. The pain was measured using the Visual Analogic Score (VAS) at 1 …

medicine.medical_specialtyTherapeutic treatmentmedicine.medical_treatmentskin rejuvenationArticle030207 dermatology & venereal diseases03 medical and health sciencesCrow's feet0302 clinical medicinePatient satisfactionMedicinedermabrasion030223 otorhinolaryngologyThermal infraredbusiness.industryDermabrasionRGeneral MedicinePerioperativevoltaic arc dermabrasionSurgerycrow’s feetVADMedicinebusinessatmospheric plasmaPost operative painGrading scaleJournal of Clinical Medicine
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