Search results for "SCAR"

Descates and the "impossible" constructions with ruler and compass

2009

Si descrivono i tentativi di Descartes di determinare quando un problema geometrico e' risolubile con riga e compasso

: School Projects in Sub-Saharan Africa: lessons learned in Guinea, Madagascar and Senegal

2006

06039 - Existe également en anglais; L'AFD et l'ADEA ont financé cette étude sur les projets d'école mis en place dans trois pays, laGuinée, Madagascar et le Sénégal. Des observations et des recueils de données ont été réalisés sur leterrain auprès des associations de parents d'élèves, des responsables administratifs, des directeursd'école et des enseignants.

Water Reuse in the Food Industry: Quality of Original Wastewater Before Treatments

2017

This chapter introduces one of the most important emergencies in the world of food and non-food industries: the availability of clean and drinking water. Water use has more than tripled globally since 1950: water quality and its scarcity are increasingly recognised as one of the most important environmental threats to humankind. In addition, the food and beverage processing industry requires copious amounts of water. For these reasons, direct and indirect water reuse systems are becoming more and more interesting and promising technologies. Different reuse guidelines have been recently issued as the result of risk assessment and management approaches linked to health-based targets. Chemical…

Degrowth, the past, the future, and the human nature

2012

Abstract In the last years, different sources point to a same message: industrial civilization has entered an overshoot mode, the natural limits to growth have been already surpassed. This frontier does not wait for us in the future; it already belongs to our past. If population and the economy are truly beyond the limits, then current visions and theories of social change would be deeply perturbed. If the development era is approaching its end, then many sociological theories on current societies will share the same destiny, sustainable development doctrines between them. It is worth to examine theories that explicitly look at the social world this way or that – at least – are not incompat…

A muscarinic mechanism inhibiting the release of noradrenaline from peripheral adrenergic nerve fibres by nicotinic agents.

1968

Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists.

2003

A series of 2,3-disubstituted indenes, which are analogues of the widely used histamine H(1) receptor antagonist dimethindene, have been synthesized and studied as muscarinic and histamine receptor antagonists. The affinities of these compounds for the five human muscarinic receptor subtypes (M(1)-M(5)) and for human histamine H(1) receptors were determined in radioligand binding studies using membranes from transfected Chinese hamster ovary (CHO) cells and [(3)H]N-methylscopolamine ([(3)H]NMS). The results demonstrate that the diisopropyl analogue 19 has a similar high affinity as (S)-dimethindene at M(2) receptors ((S)-dimethindene: pK(i) = 7.52; (-)-19: pK(i) = 7.37) with an improved sel…

Abatellis: Un punto sull’Allestimento di Scarpa 1953-54

2021

Palazzo Abatellis, ultimato alla fine del XV secolo, subì profondi rimaneggiamenti in seguito alla sua trasformazione in convento. Il visitatore si trova di fronte a uno straordinario palinsesto progettuale, composto tra il 1490 e il 1953, dall'inizio dei lavori di Matteo Carnilivari alla conclusione dei lavori della Galleria Nazionale di Sicilia su disegno di Carlo Scarpa. Tutto questo va salvaguardato o forse è necessario fare degli “aggiustamenti” per esigenze temporanee e transitorie? Palazzo Abatellis, completed at the end of the 15th century, underwent profound alterations following its transformation into a convent. The visitor is faced with an extraordinary planning schedule, compos…

Profile of glycopyrronium for once-daily treatment of moderate-to-severe COPD

2012

Bronchodilators are central in the symptomatic management of chronic obstructive pulmonary disease (COPD). Long-acting muscarinic antagonists (LAMAs) and long-acting β(2)-agonists (LABAs) are the main classes of long-acting bronchodilators. To date, tiotropium is the only once-daily LAMA available for the treatment of COPD. Glycopyrronium is a novel LAMA, currently in development for COPD. Phase II studies have shown that glycopyrronium 50 μg once daily provides clinically significant 24-hour bronchodilation with a rapid onset of action, which is faster than that of tiotropium, and a favorable safety and tolerability profile. The Phase III GLycopyrronium bromide in COPD airWays (GLOW) progr…

Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

2016

Marco Contoli,1 Paolo Solidoro,2 Fabiano Di Marco,3,4 Nicola Scichilone,5 Angelo Corsico,6 Fulvio Braido,7 Pierachille Santus4,8 1Research Centre on Asthma and COPD, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Cardiovascular and Thoracic Department, Città della Salute, Turin, Italy; 3Department of Health Sciences, University of Milan, Milan, Italy; 4Respiratory Unit, San Paolo Hospital, Milan, Italy; 5Department of Internal Medicine, Section of Pulmonology (DIBIMIS), University of Palermo, Palermo, Italy; 6Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 7Allergy and Respiratory Diseases Clinic, DIMI, University of G…

Application of the group method of data handling (GMDH) approach for landslide susceptibility zonation using readily available spatial covariates

2022

Abstract Landslide susceptibility (LS) mapping is an essential tool for landslide risk assessment. This study aimed to provide a new approach with better performance for landslide mapping and adopting readily available variables. In addition, it investigates the capability of a state-of-the-art model developed using the group method of data handling (GMDH) to spatially model LS. Furthermore, hybridized models of GMDH were developed using different metaheuristic algorithms. The study area was the Bonghwa region of South Korea, for which an accurate landslide inventory dataset is available. We considered a total of 13 spatial covariates (altitude, slope, aspect, topographic wetness index, val…