Search results for "SCOPE"
showing 10 items of 2420 documents
Light field propagation by metal micro- and nanostructures
2001
The ability to sustain plasmon oscillations gives rise to unique properties of metal nanostructures, which can be exploited for the controlled manipulation of light fields on the nanoscale. In this context we investigate electromagnetic coupling effects within lithographically produced ensembles of gold nanoparticles with a photon scanning tunnelling microscope. To provide an interface between these nano-optical devices and classical far-field optics, we investigate surface plasmon propagation on microstructured metal thin films.
In vivo detection of cytokeratin filament network breakdown in cells treated with the phosphatase inhibitor okadaic acid.
2001
We have previously described vulva carcinoma-derived A-431 subclone AK13-1, which stably expresses fluorescently labeled cytokeratin filaments (CKFs). Time-lapse fluorescence microscopy of these cells permits the continuous monitoring of the dynamics of the CKF cytoskeleton in vivo. To study mechanisms and principles of CKF disassembly as it occurs, e.g., during mitosis and liver disease, we have treated cells with the phosphatase inhibitor okadaic acid (OA), which induces complete CKF network breakdown within 3–5 h without significantly affecting the organization of the actin- and tubulin-based cytofilaments. In time-lapse movies, we find that the network breakdown starts at the cell perip…
Imaging connected porosity of crystalline rock by contrast agent-aided X-ray microtomography and scanning electron microscopy
2017
We set out to study connected porosity of crystalline rock using X-ray microtomography and scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDS) with caesium chloride as a contrast agent. Caesium is an important radionuclide regarding the final deposition of nuclear waste and also forms dense phases that can be readily distinguished by X-ray microtomography and SEM-EDS. Six samples from two sites, Olkiluoto (Finland) and Grimsel (Switzerland), where transport properties of crystalline rock are being studied in situ, were investigated using X-ray microtomography and SEM-EDS. The samples were imaged with X-ray microtomography, immersed in a saturated caesium chlorid…
Conservative upper limits on WIMP annihilation cross section from Fermi-LAT $γ$-rays
2011
The spectrum of an isotropic extragalactic {\gamma}-ray background (EGB) has been measured by the Fermi-LAT telescope at high latitudes. Two new models for the EGB are derived from the subraction of unresolved point sources and extragalactic diffuse processes, which could explain from 30% to 70% of the Fermi-LAT EGB. Within the hypothesis that the two residual EGBs are entirely due to the annihilation of dark matter (DM) particles in the Galactic halo, we obtain stringent upper limits on their annihilation cross section. Severe bounds on a possible Sommerfeld enhancement of the annihilation cross section are set as well. Finally, we consider models for DM annihilation depending on the inver…
Introduction: A New Look at the Origins of Economic Growth and Regional Inequality
2018
The contributions to this special issue share important themes and methodologies in their quest to explicate economic development and its effects. Nonetheless, each area under examination has its own peculiarities and warrants its own scope of analysis. The result is a special issue that pursues an innovative line of research, exploring parallels and contrasts in economic growth and inequality based on new data at the regional, rather than simply the national, level. The authors are grateful to the following institutions for their financial support of the research in this special issue of The Journal of Interdisciplinary History: (1) European Union (EU— Jean Monnet Action); (2) ICREA—Genera…
Indirect dark matter search with the ANTARES neutrino telescope
2012
Using the data recorded by the ANTARES neutrino telescope during 2007 and 2008, a search for high energy neutrinos coming from the direction of the Sun has been performed. The neutrino selection criteria have been chosen so as to maximize the rejection of the atmospheric background with respect to possible signals produced by the self-annihilation of weakly interactive massive particles accumulated in the centre of the Sun. After data unblinding, the number of neutrinos observed was found to be compatible with background expectations. The results obtained were compared to the fluxes predicted by the Constrained Minimal Supersymmetric Standard Model, and 90% upper limits for this model were …
Patient’s Cross-border Mobility Directive: Application, Performance and Perceptions Two Years after Transposition
2016
Abstract This paper seeks to analyse the directive on the application of patients’ rights in cross-border healthcare. Two years after the transposition, it is time for first evaluations of its application, performance and perception. The analysis consists of three major elements: reconstruction of the legal scope and subject matter of the new legislation, conclusions of the evaluative reports monitoring its implementation and performance as well as the public opinion polls revealing the EU citizens’ perception of its details. These three components combined together deliver a picture of the state of play about the pan-European cross-border patients’ mobility. The bottomline conclusions nega…
El inicio de la vida humana y el alcance de su protección jurídica en la jurisprudencia europea e internacional
2014
The international human rights treaties recognize the right to life, but most of them do not determine if the unborn is within its scope and what the degree of protection. Given this lack of specificity, the interpretation and application of this fundamental right by its supervisory bodies is particularly important. The analysis of existing case law about it - mainly from Europe - will enable us to contribute to the definition of subjective and objective scope of the protection of the unborn.
Dual drug-loaded halloysite hybrid-based glycocluster for sustained release of hydrophobic molecules
2016
A dual drug-loaded HNT–CD glycocluster delivery system based on halloysite nanotubes and carbohydrate functionalized cyclodextrin was developed by a green protocol using solvent-free microwave irradiation. The nanohybrid was employed for concurrent load and release of silibinin and curcumin. The new delivery system was characterized by means of TGA, FT-IR spectroscopy, SEM and DLS. These techniques confirm the successful loading of the two drugs in the system. SEM and DLS measurements highlighted that the nanomaterial preserves a tubular structure with an average hydrodynamic radius of ca. 200 nm. The release of the drugs from the HNT glycocluster was investigated by means of UV-vis spectro…
Sensitivity of scope modelled GPP and fluorescence for different plant functional types
2014
This study addresses the question which factors are responsible for reported positive correlations between solar induced fluorescence (SIF) and gross primary production (GPP). A sensitivity analysis of the model SCOPE, which simulates photosynthesis, fluorescence emission and radiative transfer in canopies, has been carried out for four different plant functional types (PFT): tropical rainforest, C4 crops, C3 crops, and tundra, located in distinct climate zones: tropical everwet (Af), tropical with seasonal drought (savannah, Aw), temperate (Cf), and continental tundra (Dfd). Literature values for structural and physiological parameters and climate reanalysis data were used as input. The ef…