Search results for "SCR"

showing 10 items of 11806 documents

A matching task as a potential technique for descriptive profile validation

2003

If panellists can successfully match products to the corresponding descriptive profiles, then the profiles can be regarded as product-relevant and valid. This work examined the ability of a trained panel to perform a matching task between products and their descriptive profiles. A 13-member panel, trained to assess eight cheeses in terms of 19 flavour attributes, performed the task based on their individually developed profiles. The panel's ability to match products to profiles was well above that expected by chance, and chi-square statistics for each of the products were significant (P<0.05). A correspondence analysis based on the group results indicated that all the products were relative…

0303 health sciencesMatching (statistics)Nutrition and Dietetics030309 nutrition & dietetics04 agricultural and veterinary sciences[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food scienceSensory analysisRegressionCorrespondence analysisCanonical analysisTask (project management)03 medical and health sciences0404 agricultural biotechnologyDiscriminantConsistency (statistics)Statistics[SDV.IDA]Life Sciences [q-bio]/Food engineeringAlgorithmComputingMilieux_MISCELLANEOUSFood ScienceMathematics
researchProduct

PspA adopts an ESCRT-III-like fold and remodels bacterial membranes

2021

Summary PspA is the main effector of the phage shock protein (Psp) system and preserves the bacterial inner membrane integrity and function. Here, we present the 3.6 A resolution cryoelectron microscopy (cryo-EM) structure of PspA assembled in helical rods. PspA monomers adopt a canonical ESCRT-III fold in an extended open conformation. PspA rods are capable of enclosing lipids and generating positive membrane curvature. Using cryo-EM, we visualized how PspA remodels membrane vesicles into μm-sized structures and how it mediates the formation of internalized vesicular structures. Hotspots of these activities are zones derived from PspA assemblies, serving as lipid transfer platforms and lin…

0303 health sciencesMembrane tubulationCryo-electron microscopyLipid bilayer fusionBiologyGeneral Biochemistry Genetics and Molecular BiologyESCRT03 medical and health sciences0302 clinical medicineMembraneMembrane fissionMembrane curvatureBiophysicsddc:610Phage shock030217 neurology & neurosurgery030304 developmental biology
researchProduct

Low-cost scalable discretization, prediction and feature selection for complex systems

2019

The introduced data-driven tool allows simultaneous feature selection, model inference, and marked cost and quality gains.

0303 health sciencesMultidisciplinary010504 meteorology & atmospheric sciencesDiscretizationComputer scienceData classificationProbabilistic logicComplex systemSciAdv r-articlesFeature selectioncomputer.software_genre01 natural sciences03 medical and health sciencesRange (mathematics)ScalabilityData miningCluster analysisAlgorithmcomputerResearch ArticlesMathematicsResearch Article030304 developmental biology0105 earth and related environmental sciences
researchProduct

When age means safety: Data to assess trends and differences on rule knowledge, risk perception, aberrant and positive road behaviors, and traffic cr…

2019

This data article examines the association between age, knowledge of traffic rules, risk perception, risky and positive behaviors on the road and traffic safety outcomes of cyclists. The data was collected using a structured self-administrable and online-based questionnaire, applied to a full sample of 1064 cyclists. The data contains 4 parts: descriptive statistics; graphical trends for each study variable according to age; Post-Hoc (Tukey-HSD) comparisons between cyclists classified in the different age groups; and, finally, the dataset for further explorations in this regard. For further information, it is convenient to read the full article entitled "Explaining Self-Reported Traffic Cra…

0303 health sciencesMultidisciplinaryDescriptive statisticsApplied psychologyHuman factors and ergonomicsPoison controllcsh:Computer applications to medicine. Medical informaticsSuicide preventionOccupational safety and healthRisk perception03 medical and health sciences0302 clinical medicineEmpirical researchInjury preventionlcsh:R858-859.7PsychologyPsychologylcsh:Science (General)030217 neurology & neurosurgery030304 developmental biologylcsh:Q1-390Data in brief
researchProduct

Comparison of odour sensory profiles performed by two independent trained panels following the same descriptive analysis procedures

2000

Odour sensory profiling of 28 associations of cheese ripening micro-organisms was performed by two panels of 10 assessors on two different sites. Sample preparation, training protocols and references, tasting procedures and scoring were similar in the two laboratories. Panel 2 used 10 attributes and panel 1 used these terms plus 4 extra descriptors. Analysis of variance and multivariate methods (canonical variate analysis, generalised procrustes analysis and STATIS) exhibited differences between assessors within a panel and between panels concerning the use of the scoring scale and the strength of product discrimination by attribute. Panel 1 was more sensitive to fruity notes and panel 2 to…

0303 health sciencesMultivariate statisticsNutrition and DieteticsDescriptive statistics030309 nutrition & dieteticsSensory system04 agricultural and veterinary sciences[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food scienceSensory analysisGeneralised procrustes analysis03 medical and health sciences0404 agricultural biotechnologyCanonical variate analysisStatistics[SDV.IDA]Life Sciences [q-bio]/Food engineeringEconometricsWine tastingAnalysis of varianceComputingMilieux_MISCELLANEOUSFood ScienceMathematics
researchProduct

Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment.

2019

The incidence of allergic diseases has increased over the past 50 years, likely due to environmental factors. However, the nature of these factors and the mode of action by which they induce the type 2 immune deviation characteristic of atopic diseases remain unclear. It has previously been reported that dietary sodium chloride promotes the polarization of T helper 17 (T(H)17) cells with implications for autoimmune diseases such as multiple sclerosis. Here, we demonstrate that sodium chloride also potently promotes T(H)2 cell responses on multiple regulatory levels. Sodium chloride enhanced interleukin-4 (IL-4) and IL-13 production while suppressing interferon-gamma (IFN-gamma) production i…

0303 health sciencesNaive T cellSodiumT cellCellchemistry.chemical_elementGeneral MedicineAtopic dermatitismedicine.disease03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurechemistryNFAT5InterferonImmunologymedicineTranscription factor030304 developmental biology030215 immunologymedicine.drug
researchProduct

Risk tables for discrimination tests

1993

Abstract Duo-trio and triangle test are often used in the food industry for the purpose of declaring two products non-distinguishable. In that situation, it is much more important to control the power of the test rather than the type 1 error risk. This paper makes available by e-mail a SAS ® macro, called BINRISKS, for computing type 1 and type 2 risks for any one-tailed binomial test and for any level of the percentage above chance to be detected. Using this macro, two sets of tables have been compiled. The first table includes for any total number of responses below 50, for any number of correct responses and for three levels of the percentage above chance to be detected, the correspondin…

0303 health sciencesNutrition and Dietetics030309 nutrition & dieteticsBinomial test04 agricultural and veterinary sciences[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food scienceDiscrimination testingTest (assessment)03 medical and health sciences0404 agricultural biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringStatisticsEconometricsTable (database)MacroComputingMilieux_MISCELLANEOUSFood ScienceTriangle testMathematicsType I and type II errorsFood Quality and Preference
researchProduct

Could selection tests detect the future performance of descriptive panellists ?

1996

Abstract This paper discusses the appropriateness of screening tests in explaining descriptive panellist performances. It is based on a case study aimed at forming a descriptive panel capable of flavour profiling Camembert cheeses. Eighteen subjects were selected using four sensory tasks evaluating smell sensitivities, olfactory knowledge, odour memory and descriptive ability. Three additional tests were proposed during the 45 hour training to evaluate the recognition memory for odours, the concentration and the verbal creativity abilities. Panellist performances were determined on repeatability and discrimination abilities, and on the complexity of the individual sensory space. Some signif…

0303 health sciencesNutrition and DieteticsScreening test030309 nutrition & dieteticsSensory system04 agricultural and veterinary sciences[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food scienceMemorization03 medical and health sciences0404 agricultural biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringPsychologySocial psychologyComputingMilieux_MISCELLANEOUSFood ScienceCognitive psychologyRecognition memory
researchProduct

New insight on the role of late indirect‐wave pathway underlying theta‐burst stimulation‐induced plasticity

2020

International audience

0303 health sciencesPhysiologyChemistryMotor CortexStimulationPlasticityEvoked Potentials MotorTranscranial Magnetic StimulationTheta burst03 medical and health sciencesIntermittent Theta Burst Stimulation0302 clinical medicine[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]corticospinal excitabilityI-waveNeuroscience030217 neurology & neurosurgeryComputingMilieux_MISCELLANEOUS030304 developmental biology
researchProduct

Vanillin cell sensor

2007

Our project for iGEM 2006 consisted of designing a cellular vanillin biosensor. We used an EnvZ -E. coli strain as a chassis, and constructed two different devices: a sensor and an actuator, assembled using OmpR-P as a standardised mediator. The sensor device contained a computation- ally designed vanillin receptor and a synthetic two-component signal transduction protein (Trz). The receptor protein was based on a ribose-binding protein as scaffold. The Trz was built by fusion of the periplasmic and transmembrane domains of a Trg protein with an EnvZ kinase domain. When the receptor complex binds Trg, an allosteric motion is propagated to the cyto- plasmic EnvZ kinase domain, resulting in a…

0303 health sciencesReceptor complex030303 biophysicsAllosteric regulationAutophosphorylationBioengineeringCell BiologyBiologyCell biology03 medical and health sciencesSynthetic biologyTransmembrane domainProtein kinase domainBiochemistry[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologySignal transductionMolecular BiologyTranscription factor030304 developmental biologyBiotechnologyIET Synthetic Biology
researchProduct