Search results for "SCRIB"
showing 10 items of 249 documents
Towards DSL for DL Lifecycle Data Management
2020
A new method based on Domain Specific Language (DSL) approach to Deep Learning (DL) lifecycle data management tool support is presented: a very simple DL lifecycle data management tool, which however is usable in practice (it will be called Core tool) and a very advanced extension mechanism which in fact converts the Core tool into domain specific tool (DSL tool) building framework for DL lifecycle data management tasks. The extension mechanism will be based on the metamodel specialization approach to DSL modeling tools introduced by authors. The main idea of metamodel specialization is that we, at first, define the Universal Metamodel (UMM) for a domain and then for each use case define a …
Uso degli inibitori di pompa protonica in un Policlinico Universitario
2012
Summary Introduction Proton pump inhibitors (PPIs) are highly prescribed drugs in Italy and in particular in the Sicilian region but little is known about their use in the hospital setting. Materials and methods PPI utilization and related costs were reviewed retrospectively by examining the pharmaceutical records of drug dispensation to the various wards of the Policlinico Universitario P. Giaccone of Palermo in 2010. Differences in the prescribing rates and drug preferences among the different clinical wards were analyzed. Results A total of 20,420 patients were hospitalized at the Policlinico of Palermo in 2010. Overall, the consumption of PPIs was 120 DDD/100 bed-days for the year 2010 …
Gender difference in drug use in hospitalized elderly patients.
2015
Purpose The aims of this study were to evaluate whether or not there are gender differences in drug use at hospital admission and prescription at discharge and to evaluate the effect of hospitalization on medication patterns in the elderly. Method In-patients aged > 65 years included in the REPOSI registry during a recruitment period of 3 years (2008-2010-2012) were analyzed in order to evaluate drug use at hospital admission and prescription at discharge according to gender. Results A total of 3473 patients, 52% women and 48% men, were considered. Polypharmacy (> 5 drugs) is more frequent in men both at hospital admission and discharge. At hospital discharge, the number of prescripti…
Polypharmacy and the risk of drug-drug interactions and potentially inappropriate medications in hospital psychiatry.
2021
PURPOSE The aim of this study was to analyze the epidemiology of polypharmacy in hospital psychiatry. Another aim was to investigate predictors of the number of drugs taken and the associated risks of drug-drug interactions and potentially inappropriate medications in the elderly. METHODS Daily prescription data were obtained from a pharmacovigilance project sponsored by the Innovations Funds of the German Federal Joint Committee. RESULTS The study included 47 071 inpatient hospital cases from eight different study centers. The mean number of different drugs during the entire stay was 6.1 (psychotropic drugs = 2.7; others = 3.4). The mean number of drugs per day was 3.8 (psychotropic drugs …
Does the internet increase the job finding rate? Evidence from a period of expansion in internet use
2021
Abstract We examine the impact of household access to the internet on job finding rates in Germany during a period (2006–2009) in which the share of households with a broadband connection increased by 31 percentage points, and job-seekers increased their use of the internet as a search tool. During this period, household access to broadband internet was almost completely dependent on the availability of a particular technology (DSL). We therefore exploit the variation in DSL availability across municipalities as an instrument for household access to the internet. OLS estimates which control for differences in individual and local area characteristics suggest a job finding advantage of about…
Hidden oscillations in aircraft flight control system with input saturation
2013
Abstract The presence of actuator saturation can dramatically degrade the system performance. Since the feedback loop is broken when the actuator saturates the unstable modes of the regulator may then drift to undesirable values. The consequences are that undesired nonlinear oscillations appear and that the settling time may unacceptably increase. Rigorous analysis of nonlinear aircraft models is a very difficult task, that is why a numerical simulation is often used as an analysis and design tool. In this paper difficulties of numerical analysis related to the existence of hidden oscillations in the aircraft control system are demonstrated.
The genetic ghost of an invasion past: colonization and extinction revealed by historical hybridization inSenecio
2011
Hybridization is an important evolutionary factor in the diversification of many plant and animal species. Of particular interest is that historical hybridization resulting in the origin of new species or introgressants has occurred between species now geographically separated by great distances. Here, we report that Senecio massaicus, a tetraploid species native to Morocco and the Canary Islands, contains genetic material of two distinct, geographically separated lineages: a Mediterranean lineage and a mainly southern African lineage. A time-calibrated internal transcribed spacer phylogeny indicates that the hybridization event took place up to 6.18 Ma. Because the southern African lineage…
Characterization of five fungal endophytes producing Cajaninstilbene acid isolated from pigeon pea [Cajanus cajan (L.) Millsp].
2011
Five fungal endophytes (K4, K5, K6, K9, K14) producing Cajaninstilbene acid (CSA, 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid) were isolated from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]. CSA is responsible for the prominent pharmacological activities in pigeon pea. The amount of CSA in culture solution varied among the five fungal endophytes. K4 produced the highest levels of CSA (1037.13 µg/L) among the endophytes tested after incubation for five days. Both morphological characteristics and molecular methods were used for species identification of fungal endophytes. The five endophytic isolates were characterized by analyzing the internal transcribed spacer (ITS) rR…
Why Africa matters: evolution of Old World Salvia (Lamiaceae) in Africa
2014
BACKGROUND AND AIMS Salvia is the largest genus in Lamiaceae and it has recently been found to be non-monophyletic. Molecular data on Old World Salvia are largely lacking. In this study, we present data concerning Salvia in Africa. The focus is on the colonization of the continent, character evolution and the switch of pollination systems in the genus. METHODS Maximum likelihood and Bayesian inference were used for phylogenetic reconstruction. Analyses were based on two nuclear markers [internal transcribed spacer (ITS) and external transcribed spacer (ETS)] and one plastid marker (rpl32-trnL). Sequence data were generated for 41 of the 62 African taxa (66 %). Mesquite was used to reconstru…
The colonization history of Olea europaea L. in Macaronesia based on internal transcribed spacer 1 (ITS-1) sequences, randomly amplified polymorphic …
2000
Phylogenetic relationships in the Olea europaea complex and the phylogeography of 24 populations of the Macaronesian olive (O. europaea ssp. cerasiformis) were assessed by using three molecular markers: nuclear ribosomal internal transcribed spacer 1 (ITS-1) sequences, randomly amplified polymorphic DNAs (RAPD), and intersimple sequence repeats (ISSR). Parsimony analysis of the ITS-1 sequences and Neighbour-joining (NJ) analyses of RAPD and ISSR banding variation revealed four major lineages in the O. europaea complex: (1) ssp. cuspidata; (2) ssp. cerasiformis from Madeira; (3) ssp. laperrinei; and (4) ssp. cerasiformis from the Canary Islands plus ssp. europaea. These results provide unequ…