Search results for "SD"
showing 10 items of 20459 documents
Expression hétérologue, repliement in vitro et caractérisation biophysique du domaine N-terminal de la sous-unité T1R3 du récepteur humain au goût su…
2010
The sweet taste receptor is a heterodimer composed of two subunits called T1R2 and T1R3. Each subunit belongs to the class C of G protein-coupled receptors and is constituted by a large extracellular N-terminal domain (NTD) linked to the transmembrane domain by a cysteine-rich region. It has been shown that T1R2 and T1R3 NTDs are both able to bind natural sugars and sucralose with distinct affinities and undergo ligand-dependent conformational change (Nie et al., Curr Biol, 2005). However, the binding properties of T1R3 NTD and the relative contribution of the two subunits to the heterodimeric receptor function remained largely unknown. To characterize the binding properties of each subunit…
BaGaTel : une base de données sur les produits laitiers, guidée par une ontologie
2019
National audience
Role of odorant-binding proteins in Drosophila melanogaster chemosensory perception
2019
Chemoperception is used by animals to detect nutritive food and avoid toxic compounds. It also allows animals to identify suitable ecological niche and mating partners. Like many other insects, Drosophila melanogaster possesses a very sensitive chemosensory ability and can detect and discriminate a wide panel of semiochemicals. Chemosensory detection is mostly mediated by olfactory and gustatory systems involving several multigene chemoreceptor families. Volatile and non-volatile chemical compounds entering the sensory organ (sensillum) must be solubilized before being transported through the hydrophilic sensillum lymph bathing the dendrites of chemosensory neurons. These perireceptor event…
T@sty: a test for assessing taste sensitivity. Description, application example
2019
The aim of the poster is to present the T@styTM device and to give an example application through results obtained in an ongoing study. The advantages and limits of this device will be discussed. T@styTM device, usable for home testing, was designed to assess human ability to detect several tastants at low concentrations in order to provide individual profiles based on sensitivity to the five tastes (sweet, salty, sour, bitter, and umami). Three test-sheets made of edible paper are used for each taste (three replicate measurements). Each test-sheet consists of six series of three precut discs (one “tasty disc” and two neutral discs) on which taste stimuli of different intensities were depos…
Flavour & saliva interaction – a brief overview
2015
Saliva is a highly complex body fluid composed of many proteins, peptides, small organic molecules and ions. Saliva is secreted at rest and during eating by major and minor salivary glands. Resting saliva is continuously bathing our oral cavity and as such stimulates our taste receptors playing thus a role in taste sensitivity against some active taste substances. Beside, during eating, foods are chewed and a significant level of stimulated saliva is rapidly incorporated in the bolus. This in-mouth phenomena impact on flavor release and thus perception through saliva-food physical interactions but also through the action of biological compounds (enzymes mainly) against the food matrix. Sali…
Taste perception: from molecule to eating behaviour
2020
The sense of taste has a role in human nutrition, it help to orient our food choices and avoid the ingestion of toxi compounds. Advances in molecular biology, cell biology an, biochemistry were used to identify and characterize the main taste receptors. The identification of these receptors allow a better understanding of the physiological processes tha govern taste perception. The presence of genetic polymorphisr in these receptors explains interindividual differences in tast perception.
New occurrence of the Ordovician eocrinoid Cardiocystites: Palaeogeographical and palaeoecological implications
2007
10 pages; International audience; Flattened eocrinoids are very rare in the fossil record, notably because of their fragility. Recent investigations in the Anti−Atlas (Morocco) have provided one of the oldest known specimens of Cardiocystites from the Upper Ordovician (early–middle Sandbian). This discovery increases the number of eocrinoid genera known in Morocco. This new material is the fifth published specimen of the genus Cardiocystites. It is well preserved, thus allowing morphological details, such as the location of the anal pyramid and the plane of thecal flattening, to be observed. Palaeoecological reconstruction can be deduced or confirmed from these new details. The respiration …
Characteristics of participation - A mathematician and a mathematics educator collaborating on a developmental research project
2018
International audience; In this paper, a developmental research project involving offering mathematical modelling (MM) activities to university biology students is presented, and a particular aspect is studied, namely the project as a collaboration between mathematicians and mathematics educators. The aim of the paper is to investigate what characterizes their participation in the project, and how the characteristics of the project and its development might influence this participation. Interview data as well as observation data from the MM sessions are analysed, and findings show that the mathematics educator served as a broker influencing the practice of the mathematician. It is hoped tha…
DESIGN E TRANSIZIONE DIGITALE : nuove sfide design-driven per l’innovazione tecno-sociale
2022
How can it be possible to work salvifically on an asphyxiated society that is beingdragged down by turbo-capitalism, the ‘soft tyranny’ of algorithms and ‘data-cracy’and marked by hegemonic and centralised socio-technical systems? Starting from the-oretical reflections and multidisciplinary contributions, this paper focuses on the strate-gic importance of techno-social innovation, critically illustrating some significant design-driven experiences that outline innovative lines of development in the field of design re-search: WASP’s experimental activity (3D printing), Manzini’s reflections on hybrid localcommunities and cities in chaotic mutation, the projects of hacktivists Persico and Ia-c…
Incompiuto, una nuova linea di partenza : progettare la differenza per un futuro sostenibile
2020
Le contemporanee costruzioni incompiute, fattispecie diffusa globalmente dell’ambiente costruito in abbandono, solo di recente sono uscite dal tabù in cui le relega l’ineludibile condizione di epifania di un fallimento. Senza entrare nel merito dei significati teoretici ad esse attribuiti (oscillanti tra i poli sovente mistificatori dell’esaltazione e della demonizzazione) e guardando alle tendenze individuabili in alcune realizzazioni degli ultimi lustri, l’articolo intende contribuire alla definizione di un approccio analitico e progettuale orientato ai multidimensionali obiettivi della sostenibilità, per rispondere in modo concreto a molteplici portatori di interesse e istanze della coll…