Search results for "SECO"
showing 10 items of 4119 documents
Fontane e acquedotti nella Sicilia tra XV e XVII secolo
2014
Between XV and XVII century, the Sicilian cities deal with impressive works of modernization, trough the construction of new conducts and aqueducts. The most eloquent signsof this activity are the precious fountains, built in Messina and Palermo, with a clear role of civic propaganda. In addition to these works, the documents tell, with reference to several cities of the island, of a lasting and dramatic series of quarrels that reveal the political and economic value of the water’s domain. Le città siciliane tra XV e XVII affrontarono una imponente opera di modernizzazione attraverso la costruzione di nuove condutture idriche e di acquedotti. La prova più evidente di questa attività so le p…
Biology and management of therapy-related acute promyelocytic leukemia.
2013
Therapy-related acute promyelocytic leukemia (t-APL) has been increasingly reported after exposure to cytotoxic and/or immunosuppressive agents given for prior malignancies or autoimmune diseases. t-APL represents both a model for better understanding human leukemogenesis and an interesting therapeutic subset which requires specific adaptations for optimal management.We discuss here potential risk factors for t-APL development and the main biologic and clinical characteristics of t-APL as compared to de-novo APL.In addition, we review therapeutic results obtained in patients with t-APL receiving conventional retinoic acid and chemotherapy and discuss new treatment opportunities with minimal…
Therapy-Related Myeloid Neoplasms in Patients With Acute Promyelocytic Leukemia Treated With All-Trans-Retinoic Acid and Anthracycline-Based Chemothe…
2010
Purpose We analyzed the incidence, risk factors, and outcome of therapy-related myeloid neoplasms (t-MNs) in patients with acute promyelocytic leukemia (APL) in first complete remission (CR). Patients and Methods From 1996 to 2008, 1,025 patients with APL were enrolled onto three sequential trials (LPA96, LPA99, and LPA2005) of the Programa Español para el Tratamiento de Enfermedades Hematológicas and received induction and consolidation therapy with all-trans-retinoic acid (ATRA) and anthracycline-based chemotherapy. Results Seventeen of 918 patients who achieved CR developed t-MN (10 with < 20% and seven with ≥ 20% of bone marrow blasts) after a median of 43 months from CR. Partial and…
Content variability of bioactive secondary metabolites in Hypericum perforatum L
2021
Abstract St John’s Wort (Hypericum perforatum L.; Hypericaceae) is a perennial medicinal herb widespread and largely used in folk medicine inside the Mediterranean basin. Many bioactive compounds have been identified within its extracts. Under a pharmacological point of view, the most important of them belong to the chemical classes of naphthodianthrones, phloroglucinols and polyphenols. Many factors have been claimed responsible for the phytochemical variability in Hypericum perforatum, such as genotype, geographical origin, harvesting stage and age of the plants. Yet, when harvested plant material is addressed to the industry, the standardization of the active ingredients over cultivation…
Diferències de sexe i edat en la disposició empàtica dels estudiants de secundària
2010
Aquest treball presenta una aproximació a l'estudi de l'empatia i de les variables que influeixen en el seu desenvolupament. L'objectiu principal és determinar en quina mesura influeixen la variable de sexe i la variable d'edat en la disposició empàtica dels adolescents. L'estudi es realitza amb una mostra d'estudiants de secundària (n = 114), homes i dones. Els resultats indiquen que les dues variables analitzades (sexe i edat) tenen un efecte significatiu sobre l'empatia. Les dones es mostren més empàtiques que els homes en totes les dimensions que mesura l'escala IRI. A mesura que avancen en edat, els adolescents mostren una major capacitat per a posar-se en el lloc de l'altre i comprend…
Theodor W. Adorno e il concetto di seconda natura nel Doktor Faustus di Thomas Mann
2018
“Doktor Faustus” of Thomas Mann, as explained by its author, is a novel on German civilization in which music plays the role of paradigm. Nevertheless the author grasps a lot of quotations from different disciplines and topics, ― e.g., theology, policy, philosophy, music, chemistry ― with the aim of depicting the creation of a second nature in music according the rules of twelve-note composition established by Arnold Schoenberg. The starting point of this complicated narrative is the reinterpretation of Theodor W. Adorno’s “Philosophie der neuen Musik”, a book that inspired Mann in tracing the idea of “second nature” created by the composer Adrian Leverkühn. The article focuses on some keyw…
Cholinergic-Adrenergic Presynaptic Interactions on the Heart in the Millisecond Range as Studied With the Pulse-to-Pulse Method
1988
A method has been devised to study the interactions of cholinergic and adrenergic nerves in the rabbit atria, a tissue known to be densely innervated by both vagus and sympathetic nerve fibres. The atria were isolated and perfused via the ascending branches of the coronary arteries. The acetylcholine (ACh) stores were labelled with [14C]-choline and the noradrenaline (NA) stores with [3H]-NA. The radioactive compounds were separated on columns and determined by scintillation spectrometry.
FACILITATING THE ADULT LEARNING PROCESSES IN SECOND CHANCE EDUCATION : WHAT DO THE LATVIAN ADULT LEARNERS AND THEIR EDUCATORS THINK ABOUT ?
2015
The paper aims at presenting the findings of the research on core competences of adult educators conducted in Latvia during the study "Identification and analysis of new challenges and solutions that have influence on engagement and reintegration of adults (18- 24 years) in lifelong learning" funded by ESF project "Support to research in educational field" (sub-activity 1.2.2.3.2.), No 011/0011/1DP/1.2.2.3.2/11/IPIA/VIAA/001. The adult educators and adult learners from the field of second chance education (evening shift schools) were involved in an online survey (2011-2012) using the research tool developed in the project “Qualified to Teach” − QF2TEACH. The main research results are analys…
Risk of second primary cancers in women diagnosed with endometrial cancer in G erman and S wedish cancer registries
2017
Along with the increasing incidence and favorable prognosis, more women diagnosed with endometrial cancer may develop second primary cancers (SPCs). We aimed at investigating risk of SPCs after endometrial cancer in Germany and Sweden to provide insight into prevention strategies for SPCs. Endometrial cancer patients diagnosed at age ≥15 years in Germany during 1997-2011 and in Sweden nationwide during 1997-2012 were selected. Standardized incidence ratios (SIRs), calculated as the ratio of observed to expected numbers of cases, were used to assess the risk of a specific second cancer after endometrial cancer for both German and Swedish datasets. Among 46,929 endometrial cancer survivors in…
Assisting relapse prevention in OCD using a novel mobile app-based intervention: A case report.
2018
Mobile health apps increase the accessibility of cognitive-behavioral–based interventions before, during, or following treatment. GGOC is a mobile app designed to challenge maladaptive beliefs in obsessive-compulsive disorder (OCD). This single-case study assesses the usefulness of GGOC as a relapse prevention tool for OCD. The patient was a 26-year-old woman with severe contamination and washing/cleaning OCD symptoms (Y-BOCS = 33). GGOC was used for relapse prevention following CBT treatment. The patient completed 47 levels dedicated to OCD-relevant maladaptive beliefs. Before and after GGOC, the Y-BOCS, Obsessive-Compulsive Inventory (OCI-R), Obsessive Beliefs Questionnaire (OBQ-20), and…