Search results for "SECR"
showing 10 items of 1169 documents
Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient
2018
Fibromyalgia is a rheumatic syndrome and its pathogenesis is controversial. The recent literature has placed considerable attention on the link between alteration of the intestinal microbiota and fibromyalgia, emphasizing the close connection between the neuroenteric system and the CNS. This study aims to evaluate the probable relationship between intestinal dysbiosis and altered secretion of hormones and vitamins such as cortisol, serotonin, Vitamin D and thyroid hormones in a patient with fibromyalgia.
Coronary Stent Strut Fractures: Classification, Prevalence and Clinical Associations
2021
Introduction. The frequency, characteristics and clinical implications of Strut fractures (SFs) remain incompletely understood. Methods and results. A total of 185 (160 patients) newer-generation drug-eluting stents (DES) were imaged. SFs were found in 21 DES (11.4%) and were classified in four patterns: one single stacked strut (41%)
Darbinieka komercnoslēpuma neizpaušanas pienākums
2016
Bakalaura darba mērķis ir noteikt darbinieka pienākumu glabāt un neizpaust darba devēja komercnoslēpumu darba tiesisko attiecību ietvaros un pēc tām, kā arī Latvijas Republikas un citu valstu normatīvo regulējumu attiecībā uz komercnoslēpuma piederību intelektuālā īpašuma tiesībām. Īstenojot mērķi, tiek apskatīti vairāki darba tiesību jautājumi saistībā ar darbinieka neizpaušanas pienākumu, kā arī konkurences ierobežojumu pēc darba tiesisko attiecību izbeigšanās. Autors norāda uz pieļaujamību noteikt Latvijas Republikas tiesību aktos komercnoslēpuma piederību intelektuālā īpašuma tiesībām, līdzīgi kā tas ir noteikts Pasaules Tirdzniecības organizācijas Līgumā par intelektuālā īpašuma tiesīb…
La fin du nucléaire? Opacité et secret défense à l'heure du débat post-Fukushima
2014
International audience
Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella
2017
The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…
tema 4_dret dels béns immaterials_dret mercantil I
2016
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València Materials docents correponents al tema 4 de l'assignatura de Dret Mercantil I del Grau de Dret. Matèries: Patents i models d'utilitat; disseny industrial; secret industrial; signes distintius
Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription fa…
2017
Background: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes. To date, little is known about the key transcriptional regulators driving these changes, and the aim of the present study was to delineate and functionally characterize the trans…
Mater semper certa est ? Passé, présent, avenir d'un adage, Actes du colloque de Dijon des 24-25 novembre 2016, K. Fiorentino et A. Fiorentino (dir.)…
2018
International audience; La preuve de la filiation maternelle, résumée par l’un des adages les plus connus en droit de la famille, Mater semper certa est, a pendant longtemps semblé être une évidence voulue par la nature, donc ne posant que peu de problème juridique, à l’inverse de la paternité. Pourtant, l’évidence a-t-elle toujours été aussi flagrante ? Pourquoi ressentir le besoin de forger un adage ? Quelle fut sa valeur et a-t-il toujours parfaitement reflété la réalité ? Force est de constater que si la maternité est certaine, la preuve de celle-ci se heurte à plusieurs difficultés tant matérielles que processuelles. Il s’agit donc ici de s’interroger sur la place accordée en droit à l…
Effect of an insect growth regulator (halofenozide) on the cuticular hydrocarbons of Culex pipiens larvae
2013
The cuticular hydrocarbons of the fourth-instar larvae of Culex pipiens aged one and six days were analysed by gas chromatography and gas chromatography-mass spectrometry. The effect of an insect growth regulator (halofenozide = RH-0345) on the cuticular hydrocarbons was evaluated using newly moulted fourth-instar larvae of C. pipiens, at the lethal concentrations (LC50 = 12.58 and LC90 = 28.58 mu g/l). A previous study revealed that RH-0345 is toxic to larvae of C. pipiens by induction of precocious larval moulting. Several cuticular hydrocarbons (CHCs) were identified and many of the other compounds remained unknown. Our data show that the CHC classes consisted of n-alkanes (C23-C29) and …
Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O
2001
The pore-forming toxin streptolysin O (SLO) can be used to reversibly permeabilize adherent and nonadherent cells, allowing delivery of molecules with up to 100 kDa mass to the cytosol. Using FITC-labeled albumin, 10 5 –10 6 molecules were estimated to be entrapped per cell. Repair of toxin lesions depended on Ca 2+ -calmodulin and on intact microtubules, but was not sensitive to actin disruption or to inhibition of protein synthesis. Resealed cells were viable for days and retained the capacity to endocytose and to proliferate. The active domains of large clostridial toxins were introduced into three different cell lines. The domains were derived from Clostridium difficile B-toxin and Clo…