Search results for "SECRETION"

showing 10 items of 764 documents

Intestinal dysbiosis and hormonal neuroendocrine secretion in the fibromyalgic patient

2018

Fibromyalgia is a rheumatic syndrome and its pathogenesis is controversial. The recent literature has placed considerable attention on the link between alteration of the intestinal microbiota and fibromyalgia, emphasizing the close connection between the neuroenteric system and the CNS. This study aims to evaluate the probable relationship between intestinal dysbiosis and altered secretion of hormones and vitamins such as cortisol, serotonin, Vitamin D and thyroid hormones in a patient with fibromyalgia.

musculoskeletal diseasesPhysiologylcsh:MedicineIntestinal dysbiosiscortisolGeneral Biochemistry Genetics and Molecular BiologyPathogenesis03 medical and health sciences0302 clinical medicineFibromyalgiaVitamin D and neurologymicrobiotaMedicineSecretion030203 arthritis & rheumatologyhormonesbusiness.industrylcsh:Rvitamin ddysbiosismedicine.diseasehumanitiesserotoninfibromyalgiaSerotoninbusinessDysbiosis030217 neurology & neurosurgeryHormoneBiomedical Papers
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Coronary Stent Strut Fractures: Classification, Prevalence and Clinical Associations

2021

Introduction. The frequency, characteristics and clinical implications of Strut fractures (SFs) remain incompletely understood. Methods and results. A total of 185 (160 patients) newer-generation drug-eluting stents (DES) were imaged. SFs were found in 21 DES (11.4%) and were classified in four patterns: one single stacked strut (41%)

musculoskeletal diseasesmedicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyArticlecoronary stent03 medical and health sciencesfluids and secretions0302 clinical medicineRestenosisInternal medicineCoronary stentmedicineddc:610cardiovascular diseases030212 general & internal medicineStent thrombosisDevice failureStent restenosisstent thrombosisoptical coherence tomographybusiness.industryRLesion ComplexityGeneral Medicinebioresorbable scaffoldequipment and suppliesmedicine.diseaseThrombosissurgical procedures operativeCardiologyMedicinebusinessBioresorbable scaffoldstent restenosisJournal of Clinical Medicine
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Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

2017

The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…

parallel evolution0301 basic medicineBartonellaAMPylation; bacterial effector; filamentation induced by cAMP; parallel evolutionVirulence FactorsIn silico030106 microbiologyBiologyfilamentation induced by cAMPGenomeEvolution MolecularType IV Secretion Systems03 medical and health sciencesBacterial ProteinsBartonella InfectionsGeneticsAMPylationHumansEvolutionary dynamicsBacterial Secretion SystemsPhylogenyEcology Evolution Behavior and SystematicsPhylogenetic treeEffectorbiology.organism_classificationbacterial effectorVirology030104 developmental biologyEvolutionary biologyFilamentation induced by cAMP; AMPylation; Parallel evolution; Bacterial effectorHost-Pathogen InteractionsParallel evolutionAdaptationBartonellaResearch Article
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Effect of an insect growth regulator (halofenozide) on the cuticular hydrocarbons of Culex pipiens larvae

2013

The cuticular hydrocarbons of the fourth-instar larvae of Culex pipiens aged one and six days were analysed by gas chromatography and gas chromatography-mass spectrometry. The effect of an insect growth regulator (halofenozide = RH-0345) on the cuticular hydrocarbons was evaluated using newly moulted fourth-instar larvae of C. pipiens, at the lethal concentrations (LC50 = 12.58 and LC90 = 28.58 mu g/l). A previous study revealed that RH-0345 is toxic to larvae of C. pipiens by induction of precocious larval moulting. Several cuticular hydrocarbons (CHCs) were identified and many of the other compounds remained unknown. Our data show that the CHC classes consisted of n-alkanes (C23-C29) and …

profiles[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]animal structures[SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT]fungicuticularculicidaepopulationsaedes-aegypti dipterainsect growth regulatorslipidsculex pipienscuticlen-alkaneshydrocarbons[ SDV.OT ] Life Sciences [q-bio]/Other [q-bio.OT]cuticle secretioncomplex
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Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O

2001

The pore-forming toxin streptolysin O (SLO) can be used to reversibly permeabilize adherent and nonadherent cells, allowing delivery of molecules with up to 100 kDa mass to the cytosol. Using FITC-labeled albumin, 10 5 –10 6 molecules were estimated to be entrapped per cell. Repair of toxin lesions depended on Ca 2+ -calmodulin and on intact microtubules, but was not sensitive to actin disruption or to inhibition of protein synthesis. Resealed cells were viable for days and retained the capacity to endocytose and to proliferate. The active domains of large clostridial toxins were introduced into three different cell lines. The domains were derived from Clostridium difficile B-toxin and Clo…

rho GTP-Binding ProteinsCell Membrane PermeabilityGlycosylationCell SurvivalBacterial ToxinsClostridium difficile toxin AClostridium difficile toxin BBiologymedicine.disease_causeCell LineBacterial ProteinsAlbuminsChlorocebus aethiopsTumor Cells CulturedmedicineAnimalsHumansSecretionParticle SizeActinMultidisciplinaryDose-Response Relationship DrugSecretory VesiclesProteinsBiological TransportDextransBiological SciencesActin cytoskeletonMolecular biologyRatsCell biologyCytosolImmunoglobulin GCOS CellsStreptolysinsras ProteinsClostridium botulinumStreptolysinProceedings of the National Academy of Sciences
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Human saliva, taste and food perception

2011

Human saliva, taste and food perception

salivagenetic structures[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritiondigestive oral and skin physiologybitternessperception gustativeinter-individual variability[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionfluids and secretionsstomatognathic systemvariabilité inter-individuelleAlimentation et NutritionFood and Nutritionamertumesalive;perception gustative;amertume;variabilité inter-individuelle;saliva;taste perception;bitterness;inter-individual variabilitysalive[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionpsychological phenomena and processestaste perception
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Mucin and α-amylase, the main salivary proteins, impact on aroma release

2014

International audience;  These data will be analyzed in regard to the following saliva parameters:  Amylase activity  Lipolytic activity  Anhydrase carbonic quantification  Lipocalines quantification  Total proteins quantity  Saliva viscosity  Saliva Flow Materials and Method  Tested molecules:  Static headspace analyses: 40min of equilibration at 30°C  Medium tested:

salivainteractionProtéine salivaire[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionstomatognathic diseasesfluids and secretionsaromastomatognathic system[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Aromes[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organsprotein[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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Consensus nomenclature for CD8(+) T cell phenotypes in cancer

2015

International audience; Whereas preclinical investigations and clinical studies have established that CD8+ T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8+ T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8+ T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8+ T cell immunity, leading to the emergence of dysfunctional CD8+ T cells. The existence of different types of CD8+ T…

senescenceT cellOncology and CarcinogenesisImmunology[SDV.CAN]Life Sciences [q-bio]/CancerBiologyCD8+ T cellsIFN gammaanergy03 medical and health sciencesstemness0302 clinical medicineImmune system[SDV.CAN] Life Sciences [q-bio]/Cancerexhaustionmedicine2.1 Biological and endogenous factorsImmunology and AllergyCytotoxic T cellAetiologyPoint of ViewCancer030304 developmental biologyCD8+ T cells; IFNγ; anergy; anticancer immunity; cytotoxicity; effector; exhaustion; senescence; stemness0303 health sciencesTumor microenvironmentCD8(+) T cellsCancermedicine.diseasePhenotype3. Good healthanticancer immunitymedicine.anatomical_structureeffectorOncologyImmunologycytotoxicityCytokine secretionCD8030215 immunologyIFNγ
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Determinación de Streptococcus mutans

2012

Se describen los pasos para determinar la presencia de Streptococcus mutans en saliva mediante un test inmunorreactivo

stomatognathic diseasesfluids and secretionsstomatognathic system32 Ciències Médiques
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Ultrastructure of posterior sternal glands of Macrotermes annandalei (Silvestri): new members of the sexual glandular set found in termites (Insecta)

2004

0362-2525 (Print) Comparative Study Journal Article; In female alates of Macrotermes annandalei, two types of abdominal glands are involved in the secretion of sex pheromone. Tergal glands are found at the anterior margin of tergites 6-10 and posterior sternal glands (PSGs) are located at the anterior margin of sternites 6-7. The cytological features of both types of glands are quite similar. The fine structural organization of PSGs is studied more precisely and described for the first time. The glandular cuticle is pitted with narrow apertures corresponding to the openings of numerous subcuticular pouches. Several Class 3 glandular units open in each pouch. One canal cell and one secretory…

stomatognathic systemSex Attractants/secretionIsoptera/physiology/*ultrastructureAbdomen/anatomy & histologyAnimalsFemaleScent Glands/secretion/*ultrastructurePhylogeny
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