Search results for "SENSORIMOTOR"

showing 10 items of 57 documents

Does the Recruitment of Excitation and Inhibition in the Motor Cortex Differ?

2007

The level of excitability within the motor cortex can be described as a balance between excitation and inhibition, but it is unknown how well both processes correlate. To address this question, the authors measured motor cortical excitability and inhibition in healthy human subjects, comparing the recruitment of motor evoked potentials (MEPs) and the duration of the cortical silent period (CSP) after transcranial magnetic stimulation (TMS). Single-pulse "focal" TMS was applied at intensities varying between 90% and 200% of motor thresholds to the right motor cortex of 15 healthy volunteers. The peak-to peak size of MEP responses and the duration of the CSP were measured in small hand muscle…

AdultMaleRecruitment NeurophysiologicalPhysiologymedicine.medical_treatmentStimulationStimulus (physiology)Inhibitory postsynaptic potentialPhysiology (medical)parasitic diseasesmedicineHumansSensorimotor cortexChemistryMotor CortexNeural InhibitionMiddle AgedEvoked Potentials MotorTranscranial Magnetic StimulationTranscranial magnetic stimulationmedicine.anatomical_structureNeurologyFemaleSilent periodNeurology (clinical)NeuroscienceExcitationMotor cortexJournal of Clinical Neurophysiology
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Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
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Temporally stable beta sensorimotor oscillations and cortico–muscular coupling underlie force steadiness

2022

Funding Information: Data and code are available on the Open Science Framework (OSF) at the following link: https://osf.io/4rmex/?view_only=7d17c2334ace4a0d83087bddf2a64a68. Scott Mongold, Thomas Legrand, and Mathieu Bourguignon were supported by the Fonds de la Recherche Scientifique (F.R.S.-FNRS, Brussels, Belgium; grant MIS F.4504.21). Harri Piitulainen was supported by the Academy of Finland (grants 266133, 296240, 326988, 327288 and 311877) including “Brain changes across the life-span” profiling funding to University of Jyväskylä. We thank Helge Kainulainen and Ronny Schreiber at Aalto NeuroImaging for providing technical help and the force sensor system for the study. We thank Riitta…

AdultMotor controlingBrain activity and meditationCognitive Neurosciencemedia_common.quotation_subjectpuristusvoimaneurofysiologialihaksetBeta sensorimotor oscillationsIsometric contractionCorticomuscular coherencePrimary sensorimotor cortexMuscle electromechanical couplingmedicineHumansMuscle SkeletalBeta (finance)media_commonMuscle forcePhysicsCore (anatomy)MEGElectromyographyMagnetoencephalographyMotor controlCoupling (electronics)Mu rhythmaivokuorihermo-lihastoimintamedicine.anatomical_structureNeurologyCerebral cortexSensorimotor CortexConsciousnessaivotNeuroscienceMuscle Contractionlihasvoima
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Cortical Proprioceptive Processing Is Altered by Aging

2018

Proprioceptive perception is impaired with aging, but little is known about aging-related deterioration of proprioception at the cortical level. Corticokinematic coherence (CKC) between limb kinematic and magnetoencephalographic (MEG) signals reflects cortical processing of proprioceptive afference. We, thus, compared CKC strength to ankle movements between younger and older subjects, and examined whether CKC predicts postural stability. Fifteen younger (range 18-31 years) and eight older (66-73 years) sedentary volunteers were seated in MEG, while their right and left ankle joints were moved separately at 2 Hz (for 4 min each) using a novel MEG-compatible ankle-movement actuator. Coherence…

Agingmedicine.medical_treatmentproprioceptiontasapainoSomatosensorySomatosensory systemCortical processing0302 clinical medicineMedicinesensorimotor integrationta315Passive movementsensorimotor cortexta515Original ResearchRehabilitation05 social sciencesSensorimotor cortexmedicine.anatomical_structurePostural stabilitypassive movementCoherenceBalancemedicine.medical_specialtyCognitive NeuroscienceSensorimotor integrationta3112koherenssi050105 experimental psychologylcsh:RC321-571somatosensory03 medical and health sciencesPhysical medicine and rehabilitationsensorisen integraation terapia0501 psychology and cognitive scienceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBalance (ability)Proprioceptionbusiness.industryagingbalanceProprioceptioncoherenceaivokuoriikääntyminenageingAnklebusiness030217 neurology & neurosurgeryLeft ankleNeuroscienceFrontiers in Aging Neuroscience
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Design and validation of a wireless Body Sensor Network for integrated EEG and HD-sEMG acquisitions

2022

Sensorimotor integration is the process through which the human brain plans the motor program execution according to external sources. Within this context, corticomuscular and corticokinematic coherence analyses are common methods to investigate the mechanism underlying the central control of muscle activation. This requires the synchronous acquisition of several physiological signals, including EEG and sEMG. Nevertheless, physical constraints of the current, mostly wired, technologies limit their application in dynamic and naturalistic contexts. In fact, although many efforts were made in the development of biomedical instrumentation for EEG and High Density-surface EMG (HD-sEMG) signal ac…

Biomedical Engineeringevoked potentialsWireless communicationSynchronizationReceiversBody sensor networkswireless body sensor networkmittauslaitteetInternal MedicineHumansEEGsensorimotor integrationBiopotential acquisition systemsHD-sEMGElectromyographyGeneral NeuroscienceRehabilitationsensoriverkotBrainSignal Processing Computer-AssistedElectroencephalographyelektromyografiahermo-lihastoimintaBiopotential acquisition systems; Body sensor networks; EEG; Electroencephalography; Electromyography; evoked potentials; HD-sEMG; Instruments; Receivers; sensorimotor integration; Synchronization; wireless body sensor network; Wireless communicationInstrumentsWireless Technologylangattomat verkot
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The body talks: Sensorimotor communication and its brain and kinematic signatures

2019

Human communication is a traditional topic of research in many disciplines such as psychology, linguistics and philosophy, all of which mainly focused on language, gestures and deictics. However, these do not constitute the sole channels of communication, especially during online social interaction, where instead an additional critical role may be played by sensorimotor communication (SMC). SMC refers here to (often subtle) communicative signals embedded within pragmatic actions - for example, a soccer player carving his body movements in ways that inform a partner about his intention, or to feint an adversary; or the many ways we offer a glass of wine, rudely or politely. SMC is a natural …

Computer scienceSocial InteractionGeneral Physics and AstronomyDeixisCode (semiotics)NO03 medical and health sciences0302 clinical medicineArtificial IntelligenceNatural (music)SemioticsHumansInterpersonal RelationsHuman communication030304 developmental biologyLanguageCognitive science0303 health sciencesGesturesCommunicationBrainAction kinematics; Joint action; Sensorimotor communication; Social coordinationJoint actionSocial coordinationSomatosensory CortexModels TheoreticalSocial relationBiomechanical PhenomenaAction kinematicsAction (philosophy)Sensorimotor communicationSensorimotor CommunicactionGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryGesture
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How is gravity integrated into motor planning : behavioural and fMRI approaches

2016

Gravity is immutable, ubiquitous and affects the dynamic of our daily movements. The gravitational attraction (9.81 m / s2) which varies less than 1% of the earth's surface, is an actress of the evolution of all living species. Thanks to an efficient sensorimotor system, the dynamical consequences of the effects of gravity on our movements are stored as internal representations. To circumvent the time delays of the afferent signals coming from the sensorimotor system (too long to plan quick movements), the Central Nervous System (CNS) acts in a proactive fashion by using suitable internal models developed during our past experiences. These models are mainly used during the motor planning to…

Contrôle moteurPlanification motriceMotor controlFMRIGravityGravitéInformations sensoriellesSensorimotor information[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Internal modelsMotor planningModèle interneIRMf
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Energy-related optimal control accounts for gravitational load: comparing shoulder, elbow, and wrist rotations.

2013

International audience; Gaveau J, Berret B, Demougeot L, Fadiga L, Pozzo T, Papaxanthis C. Energy-related optimal control accounts for gravitational load: comparing shoulder, elbow, and wrist rotations. J Neurophysiol 111: 4-16, 2014. First published October 16, 2013; doi: 10.1152/jn.01029.2012.-We permanently deal with gravity force. Experimental evidences revealed that moving against gravity strongly differs from moving along the gravity vector. This directional asymmetry has been attributed to an optimal planning process that optimizes gravity force effects to minimize energy. Yet, only few studies have considered the case of vertical movements in the context of optimal control. What kin…

DYNAMICSAdultMaleGravity (chemistry)REPRESENTATIONShoulderRotationPhysiologyMovementTORQUE-CHANGE MODELContext (language use)[ SCCO.PSYC ] Cognitive science/PsychologyKinematicsRotationModels Biologicaloptimal controlFEEDBACK-CONTROLGRAVITYControl theoryElbowTorqueHumansgravity forceMathematicsdistal[SCCO.NEUR]Cognitive science/NeuroscienceGeneral NeuroscienceMOTOR ADAPTATIONWork (physics)reaching movementVertical planeWristBiomechanical PhenomenaJerkproximalSAGITTAL PLANE[SCCO.PSYC]Cognitive science/Psychology[ SCCO.NEUR ] Cognitive science/NeuroscienceThermodynamicsNEURAL-CONTROL[ SCCO ] Cognitive scienceTRAJECTORIESsensorimotor controlARM POINTING MOVEMENTSGravitation
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‘You play like a Woman!’ Effects of gender stereotype threat on Women's performance in physical and sport activities: A meta-analysis

2018

Abstract Objectives The purpose of this quantitative review was to provide an estimation of the effect of stereotype threat on women's performance in sport. Design This review employed a meta-analytic technique. Method a meta-analysis with random effects model was performed on 24 effects. Publication bias was tested through funnel plots and Egger's regression test. Results Findings show a symmetric distribution of effects, making it possible to conclude that no file-drawer problem affected the collected sample of effects. Aggregating the results of the reviewed studies, a medium effect of stereotype threat manipulation on women's sport performances emerged (d = 0.33). Collected studies were…

Funnel plotstereotype threat women meta-analysis gender stereotypes sport performances working memory sensorimotor activitiesSocial stigmamedia_common.quotation_subject05 social sciences050109 social psychologySample (statistics)StereotypePublication biasRandom effects model050105 experimental psychologyStereotype threatMeta-analysis0501 psychology and cognitive sciencesPsychologySocial psychologySettore M-PSI/05 - Psicologia SocialeApplied Psychologymedia_common
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Long-term effects of delayed motherhood in mice on postnatal development and behavioural traits of offspring

2003

BACKGROUND: Some epidemiological evidence tentatively suggests that children born to older parents may have lower intellectual development and maturity than children whose parents are younger. This study aims to analyse the long-term effects of delayed motherhood in mice on postnatal development and behavioural traits later in life. METHODS: Hybrid females, either at the age of 10 weeks or 51 weeks, were individually housed with a randomly selected 12-14 week old hybrid male. After a postweaning resting period of 1 week, dams were caged again with a new randomly selected 12-14 week old male. This sequence of events was repeated until old females reached the end of their reproductive life. R…

GerontologyIntellectual developmentOffspringPhysiologyMorris water navigation taskReproductive BehaviorGrowthMotor ActivityBiologyDiscrimination LearningMicePregnancySensorimotor integrationAvoidance LearningAnimalsHumansAdvanced maternal ageYoung adultMaze LearningBehavior AnimalReproductionRehabilitationReproductive lifeObstetrics and GynecologyMice Inbred C57BLReproductive MedicineAgeingModels AnimalMice Inbred CBAFemaleMaternal AgeHuman Reproduction
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