Search results for "SERVICES"

showing 10 items of 2031 documents

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.

2017

Hypertension represents a major cardiovascular risk factor. The pathophysiology of increased blood pressure (BP) is not yet completely understood. Transcriptome profiling offers possibilities to uncover genetics effects on BP. Based on 2 populations including 2549 individuals, a meta-analyses of monocytic transcriptome-wide profiles were performed to identify transcripts associated with BP. Replication was performed in 2 independent studies of whole-blood transcriptome data including 1990 individuals. For identified candidate genes, a direct link between long-term changes in BP and gene expression over time and by treatment with BP-lowering therapy was assessed. The predictive value of pro…

0301 basic medicineMaleCandidate geneGene ExpressionGenome-wide association studyBlood Pressure030204 cardiovascular system & hematologyCardiorespiratory Medicine and HaematologyCardiovascularLMNATranscriptome0302 clinical medicineRisk FactorsCEBPAGene expression2.1 Biological and endogenous factorsAetiologyGeneticsMyelin and Lymphocyte-Associated Proteolipid ProteinsBlood Pressure ; Gene Expression ; Genome-wide Association Study ; Hypertension ; Transcriptomeblood pressureGenomicsSingle NucleotideLIM Domain Proteinsblood pressure; gene expression; genome-wide association study; hypertension; transcriptomeStrokeHeart DiseaseHypertensionPublic Health and Health ServicesBiomarker (medicine)FemaleEssential HypertensionPoly(ADP-ribose) PolymerasesBiotechnologyAdulthypertensionClinical SciencesNucleoside Transport ProteinsBiologyPolymorphism Single NucleotideArticle03 medical and health sciencesClinical ResearchInternal MedicineGeneticsHumansPolymorphismgenome-wide association studyGene Expression ProfilingHuman GenomeBlood Pressure DeterminationGene expression profiling030104 developmental biologyGood Health and Well BeingCardiovascular System & Hematologygene expressionCCAAT-Enhancer-Binding ProteinsCarrier ProteinstranscriptomeTranscription Factors
researchProduct

Home-Delivered Meals: Characterization of Food Intake in Elderly Beneficiaries

2021

Objective. In this study, we focus on elderly people (≥70 years old) benefiting from a home delivery meal service as part of a social welfare program. We aimed to: (i) assess the gap between the recommended and actual nutritional intake in this population and (ii) study the relationship between the intake of nutrients and the variables characterizing the participants’ health and nutritional status. Design. A dietary survey (24-hour record) was conducted during a home interview, with 64 people receiving a home delivery meal service (75% women

0301 basic medicineMaleFood intakeProtein–energy malnutritionPopulationOverweightDiet SurveysArticleprotein-energy malnutritionhome care servicesInterviews as Topic03 medical and health sciencesEating0302 clinical medicineHome delivered mealsEnvironmental healthmedicineHumansDietary surveyTX341-641nutritional intake030212 general & internal medicineeducationGeriatric Assessmentolder adultsAged2. Zero hungerAged 80 and overMealeducation.field_of_study030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryNutrition. Foods and food supply[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyFood Servicesmedicine.disease3. Good healthMalnutritionmeals-on-wheelsFemalemedicine.symptombusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceProgram EvaluationNutrients
researchProduct

An international registry for primary ciliary dyskinesia

2016

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder leading to chronic upper and lower airway disease. Fundamental data on epidemiology, clinical presentation, course and treatment strategies are lacking in PCD. We have established an international PCD registry to realise an unmet need for an international platform to systematically collect data on incidence, clinical presentation, treatment and disease course.The registry was launched in January 2014. We used internet technology to ensure easy online access using a web browser under www.pcdregistry.eu. Data from 201 patients have been collected so far. The database is comprised of a basic data form including demographic…

0301 basic medicineMalePediatricsDiseaseMedical and Health Sciences0302 clinical medicineForced Expiratory VolumeEpidemiologyMedicineCorticosteroidRegistriesYoung adult610 Medicine & healthChildIntersectoral Collaborationhealth care economics and organizationsPrimary ciliary dyskinesiaΑntibiotic agentIncidence (epidemiology)IncidenceMiddle AgedEuropeChild PreschoolDisease ProgressionFemale360 Social problems & social servicesHumanPulmonary and Respiratory MedicineAdultmedicine.medical_specialtyAdolescenteducationMEDLINE03 medical and health sciencesYoung AdultAge Distributionotorhinolaryngologic diseasesHumansAgedInternetbusiness.industryKartagener SyndromePatient SelectionInfantmedicine.diseaserespiratory tract diseases030104 developmental biology030228 respiratory systemOther Medical SciencesNorth AmericaResearch studiesObservational studyBronchodilating agentbusiness
researchProduct

Possible effects of a free, healthy school meal on overall meal frequency among 10–12-year-olds in Norway: the School Meal Project

2018

Abstract Objective To evaluate possible effects of intake of a free, healthy school meal on overall meal frequency among 10–12-year-olds in Norway. This was evaluated using a quasi-experimental school-based intervention study assessing children’s meal frequency retrospectively using a questionnaire in two elementary schools in the southern part of Norway in 2014/15. Multiple logistic regression analyses with breakfast, lunch, dinner, supper as dependent variables were used. Results A total of 164 children at baseline; 55 children in the intervention group and 109 children in the control group were included. The serving of a free school meal every day for 1 year did not improve the overall m…

0301 basic medicineMaleSupperFree school meallcsh:MedicineInterventionLogistic regressionGeneral Biochemistry Genetics and Molecular BiologyOddsVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciences0302 clinical medicineSurveys and QuestionnairesMedicineHumansFree school meal030212 general & internal medicineChildlcsh:Science (General)MealsChildrenlcsh:QH301-705.5Retrospective StudiesMeal030109 nutrition & dieteticsSchoolsbusiness.industryNorwaydigestive oral and skin physiologylcsh:RFood ServicesGeneral MedicineOdds ratioSchool mealConfidence intervalMeal frequencyResearch NoteLogistic ModelsLunchSocioeconomic Factorslcsh:Biology (General)FemalebusinessEnergy IntakeDemographylcsh:Q1-390BMC Research Notes
researchProduct

Intervention study on school meal habits in Norwegian 10-12-year-old children.

2017

Aim: The aim of this study was to investigate whether a free school meal every day was associated with children’s intake of healthy food during school. Methods: A non-randomized study design with an intervention and a control group was used to measure change in children’s meal habits at lunchtime. In total, 164 children participated; 55 in the intervention group and 109 in the control group. Children in the intervention group were served a free, healthy school meal every school day. Participating children completed a questionnaire at baseline and at 6 months’ follow up. Possible associations were evaluated with a healthy food score, which was calculated based on a food frequency questionna…

0301 basic medicineMalemedicine.medical_specialtyFree school mealIntervention groupNorwegian03 medical and health sciencesIntervention (counseling)MedicineHumansChildSchool Health ServicesMeal030109 nutrition & dieteticsbusiness.industryNorwaydigestive oral and skin physiologySignificant differencePublic Health Environmental and Occupational HealthFood ServicesGeneral MedicineFeeding BehaviorSchool mealIntervention studieslanguage.human_languageLunchlanguagePhysical therapyFemaleDiet HealthybusinessFollow-Up StudiesScandinavian journal of public health
researchProduct

High microbial diversity promotes soil ecosystem functioning

2018

ABSTRACT In soil, the link between microbial diversity and carbon transformations is challenged by the concept of functional redundancy. Here, we hypothesized that functional redundancy may decrease with increasing carbon source recalcitrance and that coupling of diversity with C cycling may change accordingly. We manipulated microbial diversity to examine how diversity decrease affects the decomposition of easily degradable (i.e., allochthonous plant residues) versus recalcitrant (i.e., autochthonous organic matter) C sources. We found that a decrease in microbial diversity (i) affected the decomposition of both autochthonous and allochthonous carbon sources, thereby reducing global CO 2 e…

0301 basic medicineMicrobial diversitySoil biodiversity[SDV]Life Sciences [q-bio]carbon mineralizationApplied Microbiology and BiotechnologyEcosystem servicesNutrient[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyEnvironmental MicrobiologySoil Microbiology2. Zero hungerchemistry.chemical_classificationEcologyEcologyredundancyMicrobiota04 agricultural and veterinary sciencesrespiratory systemfunctional redundancy[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyBiotechnologypriming effect[ SDV.SA.SDS ] Life Sciences [q-bio]/Agricultural sciences/Soil studyContext (language use)[SDV.BID]Life Sciences [q-bio]/Biodiversity[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil studyCarbon cycle03 medical and health sciencessoil organic matterOrganic matterEcosystem14. Life underwaterEcosystem[ SDV.BID ] Life Sciences [q-bio]/BiodiversityBacteria[ SDV ] Life Sciences [q-bio]Soil organic matterFungi15. Life on landCarbonfunctional030104 developmental biologychemistry13. Climate actionmicrobial diversity040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental sciencehuman activitiesFood Science
researchProduct

A Snapshot on MRSA Epidemiology in a Neonatal Intensive Care Unit Network, Palermo, Italy

2016

Objectives. We performed a one-year prospective surveillance study on MRSA colonization within the five NICUs of the metropolitan area of Palermo, Italy. The purpose of the study was to assess epidemiology of MRSA in NICU from a network perspective. Methods. Transfer of patients between NICUs during 2014 was traced based on the annual hospital discharge records. In the period February 2014 – January 2015, in the NICU B, at the University teaching hospital, nasal swabs from all infants were collected weekly, whereas in the other four NICUs (A, C, D, E) at four week-intervals of time. MRSA isolates were submitted to antibiotic susceptibility testing, SCCmec typing, PCR to detect lukS-PV and l…

0301 basic medicineMicrobiology (medical)medicine.medical_specialtyNeonatal intensive care unithealth care facilities manpower and services030106 microbiologylcsh:QR1-502MRSAMicrobiologylcsh:Microbiology03 medical and health sciencesInternal medicineEpidemiologyMedicineInfection controlnetwork approachOriginal ResearchNICuActive surveillance; Molecular typing; MRSA; Network approach; NICu; Microbiology; Microbiology (medical)business.industryMRSA colonizationactive surveillancemolecular typingSequence typesVariable number tandem repeat030104 developmental biologyMultilocus sequence typingUniversity teachingbusinessFrontiers in Microbiology
researchProduct

Influenza vaccination of healthcare workers in Italy: could mandatory vaccination be a solution to protect patients?

2019

Several studies have reported that influenza infections in healthcare workers (HCWs) can lead to nosocomial outbreaks. HCWs can potentially be infected with influenza every year, and may continue to work, encouraging the spread of the virus. Different strategies, such as informative interventions on influenza and influenza vaccination, ‘onsite’ vaccination weeks, communicative strategies through dedicated web and social media pages, and mandatory informed dissent form, were organized for HCWs working at the University Hospital of Palermo, during previous influenza seasons. However, the increased vaccination rates observed among HCWs still remain far from the 75% recommended by Public Healt…

0301 basic medicineMicrobiology (medical)medicine.medical_specialtyVaccination CoverageAttitude of Health Personnelhealth care facilities manpower and servicesHealth Personneleducation030106 microbiologyPsychological interventionMandatory ProgramsSettore MED/42 - Igiene Generale E ApplicataMicrobiologyInfectious Disease Transmission Professional-to-PatientHospitals University03 medical and health sciencesHealth careInfluenza HumanmedicineHumansNosocomial outbreakbusiness.industryPublic healthVaccinationvirus diseasesUniversity hospitalMandatory vaccinationcommunication strategies healthcare workers influenza disease perception influenza vaccination mandatory vaccinationVaccination030104 developmental biologyItalyInfluenza VaccinesFamily medicinebusinessFuture microbiology
researchProduct

Large Blooms of Bacillales (Firmicutes) Underlie the Response to Wetting of Cyanobacterial Biocrusts at Various Stages of Maturity.

2018

ABSTRACT Biological soil crusts (biocrusts) account for a substantial portion of primary production in dryland ecosystems. They successionally mature to deliver a suite of ecosystem services, such as carbon sequestration, water retention and nutrient cycling, and climate regulation. Biocrust assemblages are extremely well adapted to survive desiccation and to rapidly take advantage of the periodic precipitation events typical of arid ecosystems. Here we focus on the wetting response of incipient cyanobacterial crusts as they mature from “light” to “dark.” We sampled a cyanobacterial biocrust chronosequence before (dry) and temporally following a controlled wetting event and used high-throug…

0301 basic medicineNutrient cycle16SLife on LandChronosequenceBeta diversityFirmicutesEcological successionecological succession[ SDV.MP.BAC ] Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyMicrobiologybiological soil crustresistance03 medical and health sciencesVirologyEcosystemSoil MicrobiologyEcosystemRibosomalBacillalesResistance (ecology)EcologyfungiBiological soil crustfood and beveragespulsed-activity event15. Life on landcarbon lossstabilityArid[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyQR1-502030104 developmental biology13. Climate actionEnvironmental scienceRNAecosystem services
researchProduct

Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the Europe…

2020

Background Irreversible sensorineural hearing loss is a common side effect of platinum treatment with the potential to significantly impair the neurocognitive, social and educational development of childhood cancer survivors. Genetic association studies suggest a genetic predisposition for cisplatin-induced ototoxicity. Among other candidate genes, thiopurine methyltransferase (TPMT) is considered a critical gene for susceptibility to cisplatin-induced hearing loss in the FDA drug label and a pharmacogenetic guideline. The aim of this cross-sectional cohort study was to confirm the genetic associations in a large pan-European population and to evaluate the diagnostic accuracy of the genetic…

0301 basic medicineOncologyMaleCancer ResearchCandidate genePharmacogenomic VariantsCancer survivorsCHILDRENAnti-neoplastic drugsVARIANTSOCT2Carboplatin0302 clinical medicineHearingRisk FactorsNeoplasmsTPMTHearing / drug effectsProspective StudiesAge of OnsetChild610 Medicine & healthPREDICTORSmedia_commonHearing Loss Sensorineural / physiopathologyeducation.field_of_studyddc:618Thiopurine methyltransferasebiologycarboplatin [Cisplatin]Neoplasms / drug therapyOrganic Cation Transporter 2EuropeOncologyCisplatin: carboplatinCisplatin / adverse effects030220 oncology & carcinogenesisChild PreschoolOrganic Cation Transporter 2 / geneticsFemaleSENSITIVITYChildhood cancer360 Social problems & social servicesCohort studyDrug-induced ototoxicitymedicine.medical_specialtyINDUCED HEARING-LOSSAdolescentMulticenter cohort studyHearing Loss SensorineuralPopulationAdverse drug reactionAntineoplastic AgentsPolymorphism Single NucleotideRisk AssessmentHearing Loss Sensorineural / chemically inducedCarboplatin / adverse effects03 medical and health sciencesACYP2OtotoxicitySDG 3 - Good Health and Well-beingInternal medicinemedicineGenetic predispositionmedia_common.cataloged_instanceHumansGenetic Predisposition to DiseaseCISPLATIN-INDUCED OTOTOXICITYEuropean unioneducationGenetic Association StudiesGenetic associationRetrospective Studiesbusiness.industryAntineoplastic Agents / adverse effectsInfant NewbornInfantOdds ratioGuidelinemedicine.diseaseOtotoxicityCOMTPharmacogenomic Testing030104 developmental biologyCross-Sectional StudiesPharmacogeneticsbiology.proteinGenetic markersHearing Loss Sensorineural / geneticsCisplatinbusinessPharmacogenetics
researchProduct