Search results for "SEV"
showing 10 items of 2553 documents
Vaikeiden mielenterveyshäiriöiden tarpeenmukainen hoito ja sen toteutuminen Kainuussa vuosina 2004-2005
2014
Vertaistuesta voimaa : erityistä tukea tarvitsevien lasten äitien elämänlaatu ja vertaistukikokemukset
2015
Erityistä tukea tarvitsevan lapsen tuen tarpeet vaikuttavat koko perheen arkeen, ja saattavat kuormittaa vanhempien jaksamista. Vanhemmat voivat esimerkiksi kokea enemmän stressaantumisen tuntemuksia, ja vanhemmuus voi kuluttaa enemmän heidän voimavarojaan. Erityistä tukea tarvitsevan lapsen vanhempia kuluttavia tekijöitä ovat esimerkiksi perheelle suunnattujen palveluiden pirstaleisuus ja lapsen tarpeisiin vastaaminen. Tutkimuksemme tarkoituksena oli selvittää erityistä tukea tarvitsevien lasten äitien vertaistukikokemuksia ja elämänlaatua. Tutkimme aihetta kolmen tutkimusongelman kautta. Ensimmäisenä tutkimusongelmana oli selvittää, miten tyytyväisiä erityistä tukea tarvitsevien lasten äi…
Immune responses during COVID-19 infection
2020
International audience; Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics. The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health care and economic systems across the world. This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. While protective humoral and cellular immune responses are usually m…
Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations.
2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents the most severe global health crisis in modern human history. One of the major SARS-CoV-2 virulence factors is nonstructural protein 1 (Nsp1), which, outcompeting with the binding of host mRNA to the human ribosome, triggers a translation shutdown of the host immune system. Here, microsecond-long all-atom simulations of the C-terminal portion of the SARS-CoV-2/SARS-CoV Nsp1 in complex with the 40S ribosome disclose that SARS-CoV-2 Nsp1 has evolved from its SARS-CoV ortholog to more effectively hijack the ribosome by undergoing a critical switch of Q/E158 and E/Q159 residues that perfects Nsp1's interactions…
The causal representation of outpatients with Crohn's disease: is there a link between psychological distress and clinical disease activity?
2013
Objectives: Because of the fluctuating and occasional character of Crohn’s disease (CD), patients have to cope with a changeable condition of health. Personal perceived control is known to be an important element of adaptation to their medical condition. The objectives of this work are to determine if perceived personal control is predictive of the clinical activity of the disease and of psychological distress (depression, anxiety). Methods: The Hospital Anxiety Depression Scale (HADS), the causal dimension scale and the Clinical Global Impression (CGI; assessing perceived severity) were administered to 160 patients affected by Crohn’s disease. Indicators of inflammation (CRP), disease dura…
Le sculture lignee
2023
Il contributo indaga le sculture lignee ubicate nella chiesa di Santa Maria la Porta di Geraci Siculo. Si tratta di opere eseguite dal XVI al XVII secolo da scultori attestati non solo nel borgo madonita ma anche in altre realtà isolane. Ogni manufatto è collocato nella pertinente temperie culturale The contribution investigates the wooden sculptures located in the church of Santa Maria la Porta in Geraci Siculo. These are works performed from the 16th to the 17th century by sculptors attested not only in the Madonie village but also in other island realities. Each artifact is placed in the pertinent cultural climate
Mental health promotion competencies in the health sector based on a Delphi study
2018
Purpose Effective public mental health policy and practice call for a trained workforce that is competent in mental health promotion and delivering on improved mental health. Systematic information on what competencies are needed for mental health promotion practice in the health sector is lacking. The purpose of this paper is to investigate these competencies for mental health promotion. Design/methodology/approach A Delphi survey was carried out to facilitate a consensus-building process on development of the competencies. Professionals (n=32) working in mental health and mental health promotion took part in the survey. The experts were asked their professional views on the needed compet…
Kansainväliset uhkakuvat edellyttävät maanpuolustustahdon säilymistä
2018
Piedošanas saistība ar piedošanu sev topošajiem pieaugušajiem ar ārpus diādes attiecību pieredzi
2017
Pētījumā tika izvirzīts mērķis, noskaidrot, vai starp piedošanu un piedošanu sev pastāv kāda saistība tiem topošajiem pieaugušajiem, kuri ir bijuši neuzticīgi. Tika izvirzīti trīs pētījuma jautājumi, lai noskaidrotu vai pastāv saistības starp piedošanu un piedošanu sev respondentiem ar dažādu attiecību pieredzi. Tika izveidots salīdzinošs starpgrupu pētījums, kurā tika izmantotas 90 respondentu aizpildītās anketas. Tie tika iedalīti trīs grupās- respondenti, kuri nav piedzīvojuši partnera neuzticību un kuri paši ir bijuši uzticīgi partnerim; respondenti, kuri ir piedzīvojuši partnera neuzticību un respondenti kuri ir bijuši neuzticīgi partnerim, katrā grupā pa 30 respondentiem. Pētījuma dal…