Search results for "SHED"
showing 10 items of 289 documents
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease
2011
Objectives: Loss of intestinal barrier function plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Shedding of intestinal epithelial cells is a potential cause of barrier loss during inflammation. The objectives of the study were (1) to determine whether cell shedding and barrier loss in humans can be detected by confocal endomicroscopy and (2) whether these parameters predict relapse of IBD. Methods: Confocal endomicroscopy was performed in IBD and control patients using intravenous fluorescein to determine the relationship between cell shedding and local barrier dysfunction. A grading system based on appearances at confocal endomicroscopy in humans was devise…
Electrophysiology and neuronal integrity following systemic arterial hypotension in a rat model of unilateral carotid artery occlusion.
2007
Patients with carotid artery stenosis may be particularly susceptible to hypotension-associated cerebral ischemia and subsequent neurological sequelae. Measuring somatosensory evoked potentials (SEP), electroencephalogram (EEG), direct current (DC) potential, and histology, we compared the temporal evolution of cortical functional perturbations as well as neuronal integrity in a model of unilateral carotid artery occlusion and systemic hypobaric hypotension (HH) at the lower limit of cerebral blood flow autoregulation (50 mm Hg). Serial measurements of EEG power spectra as well as SEP-amplitudes and latencies of N10.3 were performed before, during, and up to 60 min after 30 min-HH (n=7) or …
Circadian variation in shedding of the oocysts of Isospora turdi (Apicomplexa) in blackbirds (Turdus merula): an adaptative trait against desiccation…
2009
5 pages; International audience; Many parasite species spend part of their life cycle in the external environment waiting for a new host. Emergence of parasites often occurs once a day, which may help to minimise mortality in an inhospitable environment and increase transition rates. Many intestinal parasites in birds are released in faeces only in the late afternoon. However, the adaptative significance of this pattern is unclear. One hypothesis is that a particular time of emergence may prevent parasite desiccation and therefore increase the parasite's life expectancy in the external environment. We tested this hypothesis experimentally using the blackbird (Turdus merula) infected with Is…
El uso de conchas marinas como soporte de útiles pulimentados: una pieza recuperada en Costamar (Castellón)
2013
[EN] The uniqueness of a polished tool discovered from the Neolithic levels of the prehistoric site of Costamar (Castellón, Spain) raised a detailed analysis both the nature of the support, which has been identified as a sea shell concerning the species Spondylus gaederopus, as well as traces of use preserved at the edge that allows us to define the tool as an adze.
Co-evolution of hydrological components under climate change scenarios in the Mediterranean area
2015
ABSTRACT The Mediterranean area is historically characterized by high human pressure on water resources. Today, while climate is projected to be modified in the future, through precipitation decrease and temperature increase, that jointly and non-linearly may affect runoff, concerns about water availability are increasing. For these reasons, quantitative assessment of future modifications in the mean annual water availability are important; likewise, the description of the future interannual variability of some hydrological components such as runoff and evapotranspiration are highly wished for water management and ecosystems dynamics analyses. This study investigates at basin spatial scale …
Human responses to Younger Dryas in the Ebro valley and Mediterranean watershed (Eastern Spain)
2011
The archaeological and chronological records of the Ebro River valley and the Mediterranean watershed (Eastern Spain) are examined to evaluate the effects of the Younger Dryas (Greenland Stadial 1) on the foragers of an area between 36
Does lake age affect zooplankton diversity in Mediterranean lakes and reservoirs? A case study from southern Italy
2010
Zooplankton assemblages of 51 lacustrine environments located in the middle of the Mediterranean Region were analysed to evaluate the existence of an ‘age effect’ in determining their structure. The analysed datasets refer to two different geographic areas, one comprising 30 natural and artificial lakes in Sicily and the other an arrangement of 21 analogous aquatic ecosystems located at the bottom of the Italian Peninsula, a more pristine area called Southern Apennine region. Most of the natural lakes are of post-glacial origin. The artificial lakes in both datasets were built in the last century and offer the opportunity to evaluate the possible short-term effects of ageing on the structur…
Las crecidas en ramblas valencianas mediterráneas
2001
This paper takes into account the characterisation of ephemeral stream hydrology from Mediterranean environments. The heavy floods that these countries suffer are due to firstly, the physical watershed features (steep slopes, scarced vegetation cover and thin soils) and, secondly, to the intense and variable rainfall. Large quantities of precipitation fall in a matter of hours, or even minutes, over very steep catchments, causing catastrophic flash-floods, with very pointed hydrographs and short time lags. Using hydrological daily data from the Rambla de la Viuda basin and five-minute data from both Barranc de Carraixet and Rambla de Poyo basins, we have analysed the rainfall- runoff proces…
In-vitro regulation of odontogenic gene expression in human embryonic tooth cells and SHED cells
2012
The bud-to-cap stage transition during early tooth development is a time when the tooth-inducing potential becomes restricted to the mesenchyme. Several key genes, expressed in the mesenchyme at this stage, are an absolute requirement for the progression of tooth development. These include the transcription factors Msx1 and Pax9. The inductive potential of tooth mesenchyme cells is a key requisite for whole-tooth bioengineering and thus identification of cells that can retain this property following expansion in culture is an important as yet unresolved, goal. We show here that in-vitro culture of embryonic human tooth mesenchyme cells and SHED cells express low levels of PAX9 and MSX1 and …
Initial viral load and decay kinetics of SARS-CoV-2 lineage B.1.1.7 in the upper respiratory tract of adults and children
2021
We read with interest the systematic review published by Walsh et al. in the Journal of Infection,1 focusing on the dynamics of SARS-CoV-2 RNA at the upper respiratory tract (URT). In this context, a novel SARS-CoV-2 variant lineage (B.1.1.7), first detected in the UK at the end of 2020 has transmission advantage over other lineages.2 Increased transmissibility of the B.1.1.7 variant has been linked to enhanced ACE2 affinity3 allegedly resulting in higher viral loads in URT, an observation that has been reported in some,3, 4, 5, 6 but not all7 large series published to date. In addition, longer duration of SARS-CoV-2 RNA shedding in URT has been reported in individuals infected by the B.1.1…